Results 11 to 20 of about 46,693 (216)

Energy deficit in parvalbumin neurons leads to circuit dysfunction, impaired sensory gating and social disability

open access: yesNeurobiology of Disease, 2016
Parvalbumin-expressing, fast spiking interneurons have high-energy demands, which make them particularly susceptible to energy impairment. Recent evidence suggests a link between mitochondrial dysfunction in fast spiking cortical interneurons and ...
Virginia M Pickel   +2 more
exaly   +3 more sources

Structural Property, Immunoreactivity and Gastric Digestion Characteristics of Glycated Parvalbumin from Mandarin Fish (Siniperca chuaisi) during Microwave-Assisted Maillard Reaction

open access: yesFoods, 2022
This study was aimed to investigate the structural and immunological properties of parvalbumin from mandarin fish during the Maillard reaction. The microwave-assisted the Maillard reaction was optimized by orthogonal designed experiments.
Jingjing Tai   +8 more
doaj   +1 more source

Evolution of the Parvalbumin Genes in Teleost Fishes after the Whole-Genome Duplication

open access: yesFishes, 2021
Parvalbumin is considered a major fish allergen. Here, we report the molecular evolution of the parvalbumin genes in bony fishes based on 19 whole genomes and 70 transcriptomes.
Subham Mukherjee   +5 more
doaj   +1 more source

Parvalbumin Role in Epilepsy and Psychiatric Comorbidities: From Mechanism to Intervention

open access: yesFrontiers in Integrative Neuroscience, 2022
Parvalbumin is a calcium-binding protein present in inhibitory interneurons that play an essential role in regulating many physiological processes, such as intracellular signaling and synaptic transmission.
Lívea Dornela Godoy   +4 more
doaj   +1 more source

Quercetin attenuates the reduction of parvalbumin in middle cerebral artery occlusion animal model

open access: yesLaboratory Animal Research, 2021
Background Calcium is a critical factor involved in modulation of essential cellular functions. Parvalbumin is a calcium buffering protein that regulates intracellular calcium concentrations.
Dong-Ju Park   +3 more
doaj   +1 more source

BACHD Mice Recapitulate the Striatal Parvalbuminergic Interneuron Loss Found in Huntington’s Disease

open access: yesFrontiers in Neuroanatomy, 2021
Huntington’s disease (HD) is a dominantly inherited, adult-onset neurodegenerative disease characterized by motor, psychiatric, and cognitive abnormalities.
Vyshnavi Rallapalle   +4 more
doaj   +1 more source

Binding of Acrylonitrile to Parvalbumin [PDF]

open access: yesToxicological Sciences, 1996
A previous study has shown that acrylonitrile (ACN) has a long half-life in rainbow trout muscle and that [14C]ACN appears to be bound to a 10,000-Da protein in muscle. The labeled protein was purified from muscle of trout exposed to [14C]ACN, separated on 20% SDS-PAGE, and digested for amino acid analysis and sequence analysis. These studies indicated
J J, Lech   +4 more
openaire   +2 more sources

Parvalbumin and parvalbumin chandelier interneurons in autism and other psychiatric disorders

open access: yesFrontiers in Psychiatry, 2022
Parvalbumin (PV) is a calcium binding protein expressed by inhibitory fast-spiking interneurons in the cerebral cortex. By generating a fast stream of action potentials, PV+ interneurons provide a quick and stable inhibitory input to pyramidal neurons and contribute to the generation of gamma oscillations in the cortex.
Pablo Juarez   +4 more
openaire   +3 more sources

Parvalbumin interneuron loss mediates repeated anesthesia-induced memory deficits in mice

open access: yesThe Journal of Clinical Investigation, 2023
Repeated or prolonged, but not short-term, general anesthesia during the early postnatal period causes long-lasting impairments in memory formation in various species.
Patricia Soriano Roque   +24 more
doaj   +1 more source

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