Results 11 to 20 of about 71,563 (292)
Parvalbumin and parvalbumin chandelier interneurons in autism and other psychiatric disorders
Frontiers in Psychiatry, 2022 Parvalbumin (PV) is a calcium binding protein expressed by inhibitory fast-spiking interneurons in the cerebral cortex. By generating a fast stream of action potentials, PV+ interneurons provide a quick and stable inhibitory input to pyramidal neurons and contribute to the generation of gamma oscillations in the cortex.
Pablo Juarez +4 more
openaire +3 more sources
Hominoid-specific calretinin-immunopositivity of the optic radiation (geniculocalcarine tract). [PDF]
Anat Rec (Hoboken)Calretinin‐immunostained coronal section through the primary (V1) and extrastriate (ExSt) cortex of the lar gibbon. Note that the optic radiation (OR) is strongly calretinin‐immunoreactive. This calretinin‐immunopositivity of the OR distinguishes the Hominoidea from other primates in terms of the neurochemistry of the OR.
Santana NNM +5 more
europepmc +2 more sources
Binding of Acrylonitrile to Parvalbumin [PDF]
Toxicological Sciences, 1996 A previous study has shown that acrylonitrile (ACN) has a long half-life in rainbow trout muscle and that [14C]ACN appears to be bound to a 10,000-Da protein in muscle. The labeled protein was purified from muscle of trout exposed to [14C]ACN, separated on 20% SDS-PAGE, and digested for amino acid analysis and sequence analysis. These studies indicated
J J, Lech +4 more
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Parvalbumin interneuron loss mediates repeated anesthesia-induced memory deficits in mice
The Journal of Clinical Investigation, 2023 Repeated or prolonged, but not short-term, general anesthesia during the early postnatal period causes long-lasting impairments in memory formation in various species.
Patricia Soriano Roque +24 more
doaj +1 more source
Frontiers in Pharmacology, 2021 The neurobiological bases of mood instability are poorly understood. Neuronal network alterations and neurometabolic abnormalities have been implicated in the pathophysiology of mood and anxiety conditions associated with mood instability and hence are ...
Antonello Pinna +2 more
doaj +1 more source
Biomolecules, 2022 Parvalbumin (PA) is a small, acidic, mostly cytosolic Ca2+-binding protein of the EF-hand superfamily. Structural and physical properties of PA are well studied but recently two highly conserved structural motifs consisting of three amino acids each (clusters I and II), which contribute to the hydrophobic core of the EF-hand domains, have been revealed.
Eugene A. Permyakov, Vladimir N. Uversky
openaire +4 more sources
Biology, 2022 Parvalbumins are small molecules with important functions in Ca2+ signaling, but their sequence comparisons to date, especially in fish, have been relatively poor. We here, characterize sequence motifs that distinguish parvalbumin subfamilies across vertebrate species, as well as those that distinguish individual parvalbumins (orthologues) in fish, and
Johannes M. Dijkstra, Yasuto Kondo
openaire +3 more sources
Expression and evaluation of IgE-binding capacity of recombinant Pacific mackerel parvalbumin
Allergology International, 2004 Background: Parvalbumin is the major and cross-reactive allergen in fish. Sufficient amounts of IgE-reactive recombinant fish parvalbumin are needed for diagnosis and immunotherapy of fish allergy.
Yuki Hamada +5 more
doaj +1 more source
Regulation of fast-spiking basket cell synapses by the chloride channel ClC-2. [PDF]
, 2010 Parvalbumin-expressing, fast-spiking basket cells are important for the generation of synchronous, rhythmic population activities in the hippocampus. We found that GABAA receptor-mediated synaptic inputs from murine parvalbumin-expressing basket cells ...
Földy, Csaba +3 more
core +1 more source
Subventricular zone stem cells are heterogeneous with respect to their embryonic origins and neurogenic fates in the adult olfactory bulb [PDF]
, 2007 Wedetermined the embryonic origins of adult forebrain subventricular zone (SVZ) stem cells by Cre-lox fate mapping in transgenic mice. We found that all parts of the telencephalic neuroepithelium, including the medial ganglionic eminence and lateral ...
C.H. Papadimitriou +8 more
core +4 more sources