Results 11 to 20 of about 117,172 (212)
Design Principles of Pancreatic Islets: Glucose-dependent Coordination of Hormone Pulses [PDF]
, 2015 Pancreatic islets are functional units involved in glucose homeostasis. The multicellular system comprises three main cell types; $\beta$ and $\alpha$ cells reciprocally decrease and increase blood glucose by producing insulin and glucagon pulses, while ...
Hara, Manami +2 more
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eLife, 2022 Somatostatin is a peptide hormone that regulates endocrine systems by binding to G-protein-coupled somatostatin receptors. Somatostatin receptor 2 (SSTR2) is a human somatostatin receptor and is highly implicated in hormone disorders, cancers, and ...
Yunseok Heo +8 more
doaj +1 more source
European Journal of Medical Research, 2023 Purpose To evaluate the effect of postoperative utilization of somatostatin after definitive surgery for duodenal fistula (DF) in preventing a recurrence.
Weiliang Tian +5 more
doaj +1 more source
Biomedicines, 2021 Neuroendocrine neoplasms (NENs) are heterogeneous neoplasms which arise from neuroendocrine cells that are distributed widely throughout the body. Although heterogenous, many of them share their ability to overexpress somatostatin receptors (SSTR) on ...
Maria Isabel del Olmo-Garcia +5 more
doaj +1 more source
Frontiers in Endocrinology, 2021 Neuroendocrine tumors overexpress somatostatin receptors, which serve as important and unique therapeutic targets for well-differentiated advanced disease.
Mayank Patel +5 more
doaj +1 more source
Somatostatin receptors in congenital hyperinsulinism: Biology to bedside
Frontiers in Endocrinology, 2022 Congenital hyperinsulinism (CHI), although a rare disease, is an important cause of severe hypoglycemia in early infancy and childhood, causing preventable morbidity and mortality.
Mirjam E. van Albada +4 more
doaj +1 more source
Role of somatostatin receptor-2 in gentamicin-induced auditory hair cell loss in the Mammalian inner ear. [PDF]
PLoS ONE, 2014 Hair cells and spiral ganglion neurons of the mammalian auditory system do not regenerate, and their loss leads to irreversible hearing loss. Aminoglycosides induce auditory hair cell death in vitro, and evidence suggests that phosphatidylinositol-3 ...
Yves Brand +7 more
doaj +1 more source
Age-dependent patterns of somatostatinergic neurons in sympathetic paravertebral ganglia
Сеченовский вестник, 2023 Aim. We aimed to determine the content of neurons expressing somatostatin (SST) and their colocalization with cells expressing tyrosine hydroxylase (TH) and neuropeptide Y (NPY) in the cranial cervical ganglion (CCG) and celiac plexus in rats ...
A. I. Emanuilov +3 more
doaj +1 more source
Current diagnosis and treatment of acute pancreatitis in China: a real-world, multicenter study
BMC Gastroenterology, 2021 Background Efficacy of pancreatic enzyme inhibitors in acute pancreatitis (AP) is unclear in China. Aims We aimed to present the current status of AP and evaluate the efficacy of pancreatic enzyme inhibitors in a larger population in China.
Chuandong Sun +3 more
doaj +1 more source
Somatostatin and somatostatin receptors in retinal diseases [PDF]
European Journal of Endocrinology, 2000 Somatostatin is a small neuropeptide that is producedin the central nervous system, where it acts as aneurotransmitter. This neuropeptide also has animportant role in the neuroendocrine system as aninhibitor of hormone release, the most strikingexample of which is the inhibition of growth hormonerelease.
van, Hagen PM +7 more
openaire +4 more sources