Results 1 to 10 of about 19,414 (147)

Combined SSTR2-targeted Analogue with 177Lu-DOTATATE radionuclide and octreotide therapy for refractory meningioma: a case report [PDF]

open access: yesFrontiers in Oncology
Meningiomas are the most common primary intracranial tumor in adults. Beyond surgery and radiation, no standard of care therapy exists. Meningiomas overexpress somatostatin receptor 2 (SSTR2), providing the rationale for somatostatin analogue-based ...
Carlen A. Yuen   +15 more
doaj   +2 more sources

Recurrent ventricular asystole during octreotide infusion in a patient with pancreatic neuroendocrine tumor: a case report [PDF]

open access: yesJournal of Medical Case Reports
Background Somatostatin analogs such as octreotide are frequently used in the prevention of carcinoid syndrome in the perioperative period following neuroendocrine tumor resection.
Nicholaos Mansolas, Ian Nesbitt
doaj   +2 more sources

Optimization of automated radiosynthesis method for [18F]AlF-NOTA-Octreotide and PET/CT imaging in neuroendocrine neoplasms [PDF]

open access: yesEJNMMI Radiopharmacy and Chemistry
Background Neuroendocrine neoplasms (NENs) represent heterogeneous tumors with increasing occurrence rate. Somatostatin receptor (SSTR) imaging using 68Ga-labeled analogs is crucial but limited by the relatively short half-life of this radionuclide along
Xiaoting Wan   +13 more
doaj   +2 more sources

Octreotide

open access: yesNeonatal Network, 2006
A CHYLOTHORAX IS CHARACTERIZED BY AN ACCUMULATION OF pleural fluid having a turbid or milky white appearance due to a high lipid and triglyceride content. This continuously draining fluid, called chyle, contains lymphocytes, proteins, and immunoglobulins.
Gregory V, Stajich, Laurel, Ashworth
europepmc   +4 more sources

Acromegaly: Pathophysiological Considerations and Treatment Options Including the Evolving Role of Oral Somatostatin Analogs

open access: yesPathophysiology, 2023
Acromegaly is a condition most commonly diagnosed in the fifth decade of life and has numerous treatment options. In this regard, Mycapssa® is the first FDA-approved oral octreotide capsule for treating acromegaly, combining the efficacy of the ...
Charles P. Daniel   +9 more
doaj   +1 more source

Octreotide [PDF]

open access: yesNew England Journal of Medicine, 1996
A peptide inhibiting the release of growth hormone was originally detected accidentally during studies of the distribution of growth hormone–releasing factor in the hypothalamus of rats. This peptide, called somatostatin, proved to be a cyclic peptide consisting of 14 amino acids.
Lamberts, Steven W.J.   +3 more
openaire   +3 more sources

Effect of Octreotide Injection on Postoperative Drainage After Neck Dissection: A Preliminary Report of a Prospective, Matched Case-Control Study [PDF]

open access: yesClinical and Experimental Otorhinolaryngology, 2016
Objectives Somatostatin inhibits lymph production and reduces lymph flow into the lymphatic duct. We hypothesized that octreotide, a long-acting somatostatin analog, would reduce drainage after neck dissection (ND) by reducing the overall lymphatic flow ...
Dongbin Ahn   +3 more
doaj   +1 more source

Octreotide in the treatment of acromegaly – the possibilities of high-dose therapy

open access: yesМедицинский совет, 2022
Octreotide is a first-generation somatostatin analog that has been used for 40 years for the medical treatment of acromegaly, both after neurosurgical intervention and as first-line treatment.
I. A. Ilovayskaya
doaj   +1 more source

Use of octreotide for prevention of pancreatic leak after pancreatoduodenectomy: study progress [PDF]

open access: yesWaike lilun yu shijian, 2022
The pancreatic leak after pancreaticoduodenectomy was one of the main causes of postoperative death, the rate of which remained high. Octreotide, an octapeptide somatostatin analogue, has been used in the prevention and treatment of postoperative ...
XU Yu, ZHANG Junfeng, HUA Rong
doaj   +1 more source

A Decade of Octreotide [PDF]

open access: yesDigestion, 1999
complications following pancreatic surgery). Somatostatin analogues including octreotide have been shown to reduce pressure in the splanchnic circulation, an effect that was exploited in the management of variceal and nonvariceal hemorrhages. Despite a widespread therapeutic application, octreotide seems to be a safe drug free of major side effects ...
M W, Büchler, C, Beglinger
openaire   +2 more sources

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