Uneventful octreotide LAR therapy throughout three pregnancies, with favorable delivery and anthropometric measures for each newborn: a case report [PDF]
Journal of Medical Case Reports, 2011 Introduction The safety of octreotide use, in its short-acting preparation, in pregnancy is still unclear. This report provides the first documentation of uneventful octreotide LAR use during three pregnancies in a woman with bronchial carcinoid ...
Naccache Deeb +5 more
doaj +3 more sources
The somatostatin analogue octreotide inhibits growth of small intestine neuroendocrine tumour cells. [PDF]
PLoS ONE, 2012 Octreotide is a widely used synthetic somatostatin analogue that significantly improves the management of neuroendocrine tumours (NETs). Octreotide acts through somatostatin receptors (SSTRs).
Su-Chen Li +8 more
doaj +5 more sources
Octreotide Counteracts IFN-γ-Induced Endothelial Inflammation. [PDF]
J Biochem Mol ToxicolABSTRACT Endothelial cells maintain vascular homeostasis through the regulation of permeability and coagulation. Interferon‐gamma (IFN‐γ), a proinflammatory cytokine released by activated T lymphocytes and natural killer cells, disrupts endothelial junctional integrity, leading to barrier dysfunction.
Fakir S +3 more
europepmc +2 more sources
Current diagnosis and treatment of acute pancreatitis in China: a real-world, multicenter study
BMC Gastroenterology, 2021 Background Efficacy of pancreatic enzyme inhibitors in acute pancreatitis (AP) is unclear in China. Aims We aimed to present the current status of AP and evaluate the efficacy of pancreatic enzyme inhibitors in a larger population in China.
Chuandong Sun +3 more
doaj +1 more source
Natural History and Management of Familial Paraganglioma Syndrome Type 1: Long-Term Data from a Large Family [PDF]
, 2020 Head and neck paragangliomas are the most common clinical features of familial paraganglioma syndrome type 1 caused by succinate dehydrogenase complex subunit D (SDHD) mutation. The clinical management of this syndrome is still unclear.
Cantisani, Vito +12 more
core +1 more source
Growth Hormone (GH)-Releasing Peptide Stimulation of GH Release from Human Somatotroph Adenoma Cells: Interaction with GH-Releasing Hormone, Thyrotropin- Releasing Hormone, and Octreotide. [PDF]
, 1994 The synthetic hexapeptide GH-releasing peptide (GHRP; His-D-Trp-Ala-Trp-D-Phe-Lys-NH2) specifically stimulates GH secretion in humans in vivo and in animals in vitro and in vivo via a still unknown receptor and mechanism.
Brockmeier, S. +7 more
core +1 more source
Therapeutic applications of octreotide in pediatric patients
The Saudi Journal of Gastroenterology, 2012 Background/Aim: We report our experience with the use of octreotide as primary or adjunctive therapy in children with various gastrointestinal disorders.
Abdulrahman Al-Hussaini, Decker Butzner
doaj +1 more source
BMC Endocrine Disorders, 2023 Background To prevent thyroid storm and ensure surgical safety, it is imperative to regulate excessive thyroid hormone levels in patients with thyrotropin-secreting pituitary adenomas (TSHoma) prior to surgery.
Runsheng Zhao, Kaiyu Fan, Weiqing Wan
doaj +1 more source
Circuit dissection of the role of somatostatin in itch and pain [PDF]
, 2018 Stimuli that elicit itch are detected by sensory neurons that innervate the skin. This information is processed by the spinal cord; however, the way in which this occurs is still poorly understood.
AJ Christensen +79 more
core +1 more source
Neoadjuvant chemotherapy with capecitabine and temozolomide for unresectable pancreatic neuroendocrine tumor. [PDF]
, 2012 Pancreatic neuroendocrine tumors (PNETs) are relatively rare tumors that arise in the endocrine cells of the pancreas. Historically, somatostatin analogues have been used in this disease primarily for symptom control and, to a limited extent, disease ...
Devata, Sumana, Kim, Edward J
core +2 more sources