Results 1 to 10 of about 677,503 (281)

Meningioma: Novel Diagnostic and Therapeutic Approaches

Biomedicines
Background/Objectives: Meningiomas are the most common intracranial tumors. Surgery and radiation therapy are the cornerstones of treatment and no standard of care therapy exists for refractory meningiomas. This manuscript aims to provide a comprehensive
Carlen A. Yuen, Michelle Zheng, Max A. Saint-Germain, David O. Kamson   +3 more
doaj   +1 more source

Somatostatin Analogs in the Medical Management of Occult Bleeding of the Lower Digestive Tract

Gastroenterology Research and Practice, 2015
The management of occult bleeding from the lower digestive tract can be very challenging. In cases of identified angiodysplasia, the first line management options can be limited by a number of clinical or anatomical factors and an alternative approach ...
Julie Martin-Grace, Gianluca Tamagno
doaj   +1 more source

Long-Term Disease Control of a Non-Operable Neuroendocrine Tumor of the Lung with Lanreotide: A Case Study

Case Reports in Oncology, 2012
Bronchopulmonary neuroendocrine tumors (NETs) are malignant tumors that represent approximately 20% of all lung cancers. The therapeutic option for advanced or metastatic bronchopulmonary NETs is mainly palliation of symptoms; options need to be ...
F. Van Fraeyenhove, E. De Droogh, N. Meireson, D. Galdermans, C. Goor, F. Van Acker, C. Mattelaer, V. De Ruyter, D. Schrijvers   +8 more
doaj   +1 more source

Somatostatin receptors in gastroentero-pancreatic neuroendocrine tumours [PDF]

, 2003
Five somatostatin receptor (sst) subtype genes, sst(1), sst(2), sst(3), sst(4) and sst(5), have been cloned and characterised. The five sst subtypes all bind natural somatostatin-14 and somatostatin-28 with high affinity.
Herder, W.W. (Wouter) de, Hofland, L.J. (Leo), Lamberts, S.W.J. (Steven), Lely, A-J. (Aart-Jan) van der   +3 more
core   +2 more sources

The influence of somatostatin analogues on the incidence of pancreatic fistulas and postoperative morbidity in patients undergoing pancreatic resection: A Bayesian network meta-analysis.

PLoS ONE
BackgroundPancreatic resection is a critical treatment for pancreatic cancer and other pancreatic diseases. Somatostatin analogs are commonly used to prevent complications following pancreatic resection, but their efficacy and safety remain debated ...
Zonghao Hou, Shengxiang Hou, Zhixin Wang, Haijiu Wang, Manjun Deng, Haining Fan   +5 more
doaj   +1 more source

Agonists, Antagonists and Receptors of Somatostatin: Pathophysiological and Therapeutical Implications in Neoplasias

Current Issues in Molecular Biology
Somatostatin is a peptide that plays a variety of roles such as neurotransmitter and endocrine regulator; its actions as a cell regulator in various tissues of the human body are represented mainly by inhibitory effects, and it shows potent activity ...
Argyrios Periferakis, Georgios Tsigas, Aristodemos-Theodoros Periferakis, Carla Mihaela Tone, Daria Alexandra Hemes, Konstantinos Periferakis, Lamprini Troumpata, Ioana Anca Badarau, Cristian Scheau, Ana Caruntu, Ilinca Savulescu-Fiedler, Constantin Caruntu, Andreea-Elena Scheau   +12 more
doaj   +1 more source

Expression of somatostatin receptors in hemangioblastomas associated with von Hippel-Lindau disease as a novel diagnostic, therapeutic, and follow-up opportunity: A case report and literature review

Archives of Endocrinology and Metabolism
SUMMARY Hemangioblastomas associated with von Hippel-Lindau (VHL) disease are frequently multiple and recur during prolonged follow-up. Currently, no systemic treatment is available for these tumors.
Eloá Pereira Brabo, Sergio Altino de Almeida, Patrícia Piazza Rafful, Paulo Henrique Rosado-de-Castro, Leonardo Vieira Neto   +4 more
doaj   +1 more source

Switch from antagonist to agonist after addition of a DOTA chelator to a somatostatin analog [PDF]

, 2018
Purpose: Peptide receptor targeting has become an increasingly attractive method to target tumors diagnostically and radiotherapeutically. Peptides linked to a variety of chelators have been developed for this purpose.
Cescato, Renzo, Erchegyi, Judit, Reubi, Jean, Rivier, Jean, Waser, Beatrice   +4 more
core  

Somatostatin and CXCR4 chemokine receptor expression in hepatocellular and cholangiocellular carcinomas: tumor capillaries as promising targets

BMC Cancer, 2017
Background Hepatocellular (HCC) and cholangiocellular carcinomas (CCC) display an exceptionally poor prognosis. Especially for advanced disease no efficient standard therapy is currently available.
Daniel Kaemmerer, Robin Schindler, Franziska Mußbach, Uta Dahmen, Annelore Altendorf-Hofmann, Olaf Dirsch, Jörg Sänger, Stefan Schulz, Amelie Lupp   +8 more
doaj   +1 more source

Combined treatment of somatostatin analogues with pegvisomant in acromegaly [PDF]

, 2016
Treatment of acromegaly with monotherapy long-acting somatostatin analogues (LA-SSA) as primary treatment or after neurosurgery can only achieve complete normalization of insulin-like growth factor I (IGF-I) in roughly 40 % of patients.
Franck, S.E. (Sanne), Lely, A-J. (Aart-Jan) van der, Muhammad, A. (Ammar), Neggers, S.J.C.M.M. (Bas)   +3 more
core   +3 more sources