Results 21 to 30 of about 27,411 (201)

Somatostatin subtype-2 receptor-targeted metal-based anticancer complexes [PDF]

, 2012
Conjugates of a dicarba analogue of octreotide, a potent somatostatin agonist whose receptors are overexpressed on tumor cells, with [PtCl 2(dap)] (dap = 1-(carboxylic acid)-1,2-diaminoethane) (3), [(η 6-bip)Os(4-CO 2-pico)Cl] (bip = biphenyl, pico ...
González, Carlos A., Moreno Martínez, Virtudes, Carrion-Salip, Dolors, González-Cantó, A., Massaguer, A., Sadler, Peter, Llorens Duran, Rafael de, Massaguer i Vall-llovera, Anna, González Ibañez, Carlos, Massaguer, Anna, de Llorens, Rafael, Carrion-Salip, D, González, Carlos, Gómez-Pinto, Irene, Sadler, P. J., Moreno, Virtudes, Barragán, F., Barragán, Flavia, Sadler, P.J., Llorens, Rafael de, Marchán Sancho, Vicente, Sadler, Peter J., Carrion Salip, Dolors, Marchán, Vicente, González-Cantó, Alejandro   +24 more
core   +1 more source

The effect of preoperative short-term octreotide treatment to surgery in thyrotropin-secreting pituitary adenomas: a retrospective cohort study

BMC Endocrine Disorders, 2023
Background To prevent thyroid storm and ensure surgical safety, it is imperative to regulate excessive thyroid hormone levels in patients with thyrotropin-secreting pituitary adenomas (TSHoma) prior to surgery.
Runsheng Zhao, Kaiyu Fan, Weiqing Wan
doaj   +1 more source

Additional file 1 of Automated GMP compliant production of [18F]AlF-NOTA-octreotide

, 2020
Additional file 1: Figure S1. Representative chromatogram (220 nm) of the formulation solution (blank). Figure S2. Radiochromatogram of [18F]AlF-NOTA-octreotide. A) Analytical chromatogram of [18F]AlF-NOTA-octreotide at the end of synthesis.
Kim Serdons (2335297), Willy Gsell (3210192), Térence Tshibangu (8376192), Christophe Deroose (3878104), Guy Bormans (419668), Frederik Cleeren (1677178), Elin Pauwels (8376195), Christopher Cawthorne (281870)   +7 more
core   +1 more source

Predictors of in vitro response to somatostatin and dopamine receptor-targeted treatments are lacking in clinically non-functioning pituitary tumors. [PDF]

J Neuroendocrinol
Abstract Clinically non‐functioning pituitary neuroendocrine tumors (NF‐PitNETs) lack effective medical therapies, and the role of somatostatin receptor ligands (SRLs) and dopamine agonists (DAs) in this setting is controversial. We evaluated the in vitro response of NF‐PitNETs to multiple SRL and/or DA treatments, focusing on the role of receptor ...
Campana C, Amarù J, Rossi DC, Arecco A, Nozza P, Boschetti M, Zona G, Ferone D, Arvigo M, Gatto F.   +9 more
europepmc   +2 more sources

Everolimus and long acting octreotide as a volume reducing treatment of polycystic livers (ELATE): study protocol for a randomized controlled trial

Trials, 2011
Background Polycystic liver disease (PLD) is defined as having more than 20 liver cysts and can present as a severe and disabling condition. Most symptoms are caused by the mass effect of the liver size and include abdominal pain and distension.
Chrispijn Melissa, Drenth Joost PH
doaj   +1 more source

The somatostatin analogue octreotide inhibits growth of small intestine neuroendocrine tumour cells. [PDF]

PLoS ONE, 2012
Octreotide is a widely used synthetic somatostatin analogue that significantly improves the management of neuroendocrine tumours (NETs). Octreotide acts through somatostatin receptors (SSTRs).
Su-Chen Li, Cécile Martijn, Tao Cui, Ahmed Essaghir, Raúl M Luque, Jean-Baptiste Demoulin, Justo P Castaño, Kjell Öberg, Valeria Giandomenico   +8 more
doaj   +1 more source

A case of antibody formation against octreotide visualized with 111In-octreotide scintigraphy [PDF]

, 1993
A case of antibody formation in a patient with carcinoid syndrome is described. The patient was treated with octreotide in dosages up to 1.5 mg/day.
Hofland, L. J., Assies, J., Lamberts, S. W., Hofland, L. J.; id_orcid, Krenning, E. P., Lamberts, S. W.J., Kwekkeboom, D. J., Reubi, J. C.   +7 more
core   +1 more source

Octreotide in Intestinal Lymphangiectasia: Lack of a Clinical Response and Failure to Alter Lymphatic Function in a Guinea Pig Model

Canadian Journal of Gastroenterology, 2004
Intestinal lymphangiectasia, which can be classified as primary or secondary, is an unusual cause of protein-losing enteropathy. The main clinical features include edema, fat malabsorption, lymphopenia and hypoalbuminemia.
S Makhija, P-Y vod der Weid, J Meddings, SJ Urbanski, PL Beck   +4 more
doaj   +1 more source

The effect of SRIH-14 or octreotide on the morphological characteristics of adrenal medulla using newcast [PDF]

Archives of Biological Sciences, 2010
The effects of chronic treatments with either SRIH-14 or octreotide on the adrenal medulla of male Wistar rats were examined. Adult males received subcutaneous (s.c.) injections of 20 μg/100 g body weight of either SRIH-14 or octreotide twice a day for ...
Trifunović Svetlana, Filipović B., Ajdžanović V., Manojlović-Stojanoski Milica, Nestorović Nataša, Sekulić Milka, Milošević Verica   +6 more
doaj   +1 more source

Use of Octreotide in the Acute Management of Bleeding Esophageal Varices

Canadian Journal of Gastroenterology, 1997
Acute hemorrhage from esophageal varices is a medical emergency; despite early diagnosis and treatment the associated hospital mortality remains high.
Daniel C Sadowski
doaj   +1 more source