Results 21 to 30 of about 19,437 (169)

Use of Octreotide in the Acute Management of Bleeding Esophageal Varices

open access: yesCanadian Journal of Gastroenterology, 1997
Acute hemorrhage from esophageal varices is a medical emergency; despite early diagnosis and treatment the associated hospital mortality remains high.
Daniel C Sadowski
doaj   +1 more source

The somatostatin analogue octreotide inhibits growth of small intestine neuroendocrine tumour cells. [PDF]

open access: yesPLoS ONE, 2012
Octreotide is a widely used synthetic somatostatin analogue that significantly improves the management of neuroendocrine tumours (NETs). Octreotide acts through somatostatin receptors (SSTRs).
Su-Chen Li   +8 more
doaj   +1 more source

Meta-analysis on the effects of octreotide on tumor mass in acromegaly. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: The long-acting somatostatin analogue octreotide is used either as an adjuvant or primary therapy to lower growth hormone (GH) levels in patients with acromegaly and may also induce pituitary tumor shrinkage.
Andrea Giustina   +5 more
doaj   +1 more source

Efficacy and safety of octreotide treatment for diazoxide‐unresponsive congenital hyperinsulinism in China

open access: yesPediatric Investigation, 2020
Importance Octreotide is an off‐label medicine for congenital hyperinsulinism (CHI), but is currently widely used for treatment of patients with CHI. Thus far, variable efficacy and adverse effects have been reported for octreotide. Objective The present
Bingyan Cao   +8 more
doaj   +1 more source

Octreotide Use in a Patient with MEN-1 Syndrome and Multifocal Pancreatic Neuroendocrine Tumors: A Case Report and Review of the Literature

open access: yesCase Reports in Gastrointestinal Medicine, 2019
We report a patient with multiple endocrine neoplasia type 1 with pancreatic polypeptide (PP) secreting subcentimeter pancreatic neuroendocrine tumors (pNETs) treated with octreotide and review the current literature that pertains to the management of ...
Matthew H. Kemm   +4 more
doaj   +1 more source

Octreotide-induced thrombocytopenia: a case report

open access: yesJournal of Medical Case Reports, 2011
Introduction Thrombocytopenia is an extremely rare complication of octreotide therapy and can be life threatening in the setting of esophageal variceal bleeding.
Rizvi Nahid, Rashidi Armin
doaj   +1 more source

Somatostatin Octapeptide Inhibits Cell Invasion and Metastasis in Hepatocellular Carcinoma Through PEBP1

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Hepatocellular carcinoma (HCC) is a major threat to human health. The condition carries a high risk of death; 45% of new cases occur in China.
Chuan-Zhong Huang   +5 more
doaj   +1 more source

Octreotide may improve pharyngocutaneous fistula healing through downregulation of cystatins: A pilot study

open access: yesLaryngoscope Investigative Otolaryngology, 2023
Background Pharyngocutaneous fistula (PCF) and salivary leaks are well known complications of head and neck surgery. The medical management of PCF has included the use of octreotide without a well‐defined understanding of its therapeutic mechanism.
Jonathan Cohen   +7 more
doaj   +1 more source

Automated GMP compliant production of [18F]AlF-NOTA-octreotide

open access: yesEJNMMI Radiopharmacy and Chemistry, 2020
Background Gallium-68 labeled synthetic somatostatin analogs for PET/CT imaging are the current gold standard for somatostatin receptor imaging in neuroendocrine tumor patients.
Térence Tshibangu   +7 more
doaj   +1 more source

Octreotide acetate enhanced radio sensitivity and induced apoptosis in MCF7 breast cancer cell line

open access: yesJournal of Radiation Research and Applied Sciences, 2022
Introduction: Breast cancer is the most common type of cancer among women. Radiotherapy is one of the treatment options for breast cancer; it plays a significant role in tumour control after surgery. However, radio resistance developed by tumour cells is
Alkhansa Salih Mahmoud   +4 more
doaj   +1 more source

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