Results 41 to 50 of about 2,232,804 (291)

Molecular pathogenesis and targeted therapy of sporadic pancreatic neuroendocrine tumors [PDF]

, 2015
Over the past few years, knowledge regarding the molecular pathology of sporadic pancreatic neuroendocrine tumors (PNETs) has increased substantially, and a number of targeted agents have been tested in clinical trials in this tumor type.
Ahn, Balogh, Bergers, Berruti, Capurso, Capurso, Carew, Castellano, Chamberlain, Chan, Chan, Chen, Clynes, Corbo, Corbo, Couvelard, De Wilde, Di Florio, Di Florio, Di Florio, Fazio, Fendrich, Gaur, Gurung, Han, Heaphy, Heaphy, Hobday, Hopfner, House, Jacinto, Jensen, Jiao, Karnik, Karnik, Komori, Kulke, Laplante, Loewith, Lovejoy, Luzi, Marinoni, Marion-Audibert, Mendel, Meric-Bernstam, Missiaglia, Mocellin, Panzuto, Papouchado, Passacantilli, Perren, Pàez-Ribes, Raymond, Sarbassov, Scoazec, Shah, Shi, Tang, Vinagre, Wang, Yang, Yao, Yuan, Zhang, Zhang   +64 more
core   +1 more source

Rare Presentation of a Metastatic Pancreatic Neuroendocrine Neoplasm Presenting with Atrial Flutter

European Journal of Case Reports in Internal Medicine, 2021
Pancreatic neuroendocrine neoplasms (PanNENs) rarely secrete serotonin, which is the main cause of carcinoid syndrome. One of its unusual manifestations is carcinoid heart disease or Hedinger’s syndrome which is seldom accompanied by cardiac arrhythmias.
Paraskevi C Fragkou, Ioannis A Papadopoulos, Antonios Papadopoulos, Evangelos-Achilleas Kontoveros, Gregory Kaltsas, Foula Vassilara   +5 more
doaj   +1 more source

Primary Mesenteric Carcinoid Tumor Presenting with Carcinoid Syndrome

Case Reports in Gastroenterology, 2018
Neuroendocrine neoplasms (NENs) are a diverse group of tumors arising throughout the body with a common origin from neuroendocrine cells. Well-differentiated NENs, also known as neuroendocrine tumors (NETs), are generally indolent and are often found ...
Oluwaseun Shogbesan, Abdullateef Abdulkareem, Binu Pappachen, John Altomare   +3 more
doaj   +1 more source

Ileal Neuroendocrine Tumour Causing Carcinoid Syndrome in Absence of Hepatic Metastasis [PDF]

Journal of Clinical and Diagnostic Research, 2023
Carcinoid syndrome consists of the classic symptom triad of flushing, diarrhoea, and valvular heart disease. It occurs in the majority of patients with liver metastases. This report presents a 68-year-old female who suffered from chronic diarrhoea with a
Iti Jain, Ameet Kumar, Balram Goyal, Prerna Guleria   +3 more
doaj   +1 more source

TELEPRO: Patient‐Reported Carcinoid Syndrome Symptom Improvement Following Initiation of Telotristat Ethyl in the Real World

The Oncologist, 2019
Patients with carcinoid syndrome diarrhea that is not controlled with long‐acting somatostatin analogs can benefit from the addition of the tryptophan hydroxylase inhibitor, telotristat ethyl.
J. Strosberg, V. Joish, S. Giacalone, Raul Perez‐Olle, Ann Fish‐Steagall, Kanika Kapoor, Sam Dharba, P. Lapuerta, A. Benson   +8 more
semanticscholar   +1 more source

Somatostatin receptor scintigraphy: Its value in tumor localization in patients with Cushing's syndrome caused by ectopic corticotropin or corticotropin-releasing hormone secretion [PDF]

, 1994
purpose: To assess the feasibility of somatostatin receptor scintigraphy for patients with Cushing's syndrome caused by tumors secreting ectopic corticotropin or corticotropin-releasing hormone (CRH).
Bruining, H.A. (Hajo), Herder, W.W. (Wouter) de, Hofland, L.J. (Leo), Kreniming, E.P. (Eric), Kwekkeboom, D.J. (Dirk Jan), Lamberts, S.W.J. (Steven), Malchoff, C.D. (Carl), Nobels, F.R.E. (Frank), Oei, H.Y. (H.), Pols, H.A.P. (Huib), Reubi, J.-C. (Jean-Claude)   +10 more
core   +1 more source

Right and Left-Sided Carcinoid Heart Disease in the Setting of Selective Serotonin Reuptake Inhibitor Use

JACC: Case Reports, 2020
Carcinoid heart disease is a complication of carcinoid syndrome. The role of selective serotonin reuptake inhibitors in carcinoid heart disease is unclear. We present a case of refractory heart failure due to right- and left-sided carcinoid heart disease
Jennifer Bell, MD, Maad Alhudairy, MD, Vera Kazakova, MD, Michael Johnstone, MD, Lana Tsao, MD   +4 more
doaj  

Long-Term Safety Experience with Telotristat Ethyl Across Five Clinical Studies in Patients with Carcinoid Syndrome.

The Oncologist, 2019
BACKGROUND Patients with neuroendocrine tumors (NETs) and carcinoid syndrome experience considerable morbidity and mortality; carcinoid syndrome may be associated with shorter survival.
L. Anthony, M. Kulke, M. Caplin, E. Bergsland, K. Öberg, M. Pavel, D. Hörsch, R. Warner, T. O'Dorisio, Joseph S. Dillon, P. Lapuerta, K. Kassler-Taub, Wenjun Jiang   +12 more
semanticscholar   +1 more source

Upper gastrointestinal symptoms in autoimmune gastritis. A cross-sectional study [PDF]

, 2017
Autoimmune gastritis is often suspected for its hematologic findings, and rarely the diagnosis is made for the presence of gastrointestinal symptoms. Aims of this cross-sectional study were to assess in a large cohort of patients affected by autoimmune ...
Annibale, Bruno, Carabotti, Marilia, Esposito, Gianluca, Lahner, Edith, Sacchi, MARIA CARLOTTA, Severi, Carola   +5 more
core   +2 more sources

Bronchial Carcinoid Tumour as a Rare Cause of Cushing’s Syndrome in Children: A Case Report and Review of Literature

JCRPE, 2020
Cushing’s syndrome (CS) is rare in childhood and adolescence. The most common paediatric cause of CS is exogenous administration of glucocorticoids; either topical, inhaled or oral corticosteroids.
Rahul Saxena, Manish Pathak, Ravindra Shukla, Arvind Sinha, Poonam Elhence, Jyotsna N. Bharti, Pushpinder Khera   +6 more
doaj   +1 more source