Results 171 to 180 of about 2,681,719 (261)

Smoothened variants explain the majority of drug resistance in basal cell carcinoma.

Cancer Cell, 2015
Scott X. Atwood, K. Sarin, R. Whitson, Jiang R. Li, G. Kim, Melika Rezaee, M. Ally, Jinah Kim, C. Yao, A. Chang, A. Oro, Jean Y. Tang   +11 more
semanticscholar   +1 more source

Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics

Advanced Healthcare Materials, EarlyView.
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins, Samuel L. Hallam, Mariah J. Austin, Adrianne M. Rosales   +3 more
wiley   +1 more source

Acantholytic Acanthoma Arising in Severely Photodamaged Skin: A Case Report. [PDF]

Cureus
Elibol BN, Erduran F, Orhun HS.
europepmc   +1 more source

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

Advanced Healthcare Materials, EarlyView.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu, Wentie Yang, Youzhi Hong, Yusen Qiao, Chaozhao Liang   +4 more
wiley   +1 more source

A Sonidegib Experience in the Treatment of Basal Cell Carcinoma with Systemic Lupus Erythematosus: A Case Report. [PDF]

Clin Cosmet Investig Dermatol
Shi L, Liu B, Gao P, Cao X, Wan C.
europepmc   +1 more source

Genomic analysis of smoothened inhibitor resistance in basal cell carcinoma.

Cancer Cell, 2015
Hayley J. Sharpe, Grégoire Pau, G. Dijkgraaf, N. Basset-Seguin, Z. Modrusan, T. Januario, V. Tsui, Alison B Durham, A. Dlugosz, Peter M. Haverty, R. Bourgon, Jean Y. Tang, K. Sarin, L. Dirix, D. Fisher, C. Rudin, H. Sofen, M. Migden, R. Yauch, F. D. de Sauvage   +19 more
semanticscholar   +1 more source

Characterization of Microplastics in Human Gastric Cancer and Control Tissues and Analysis of Associated Genetic Features

Advanced Healthcare Materials, EarlyView.
This study characterizes the presence of microplastics in human normal gastric, para‐tumor, and gastric tumor tissue and confirms the association between microplastic exposure and lymph node metastasis in gastric cancer. This study explores the transcriptomic changes induced by microplastic exposure, laying the foundation for further investigation into
Liqiao Chen, Jialin Li, Yan Wu, Han Bao, Xuesong Yang, Guoqing Lv, Ke Ji, Ji Zhang, Xiaojiang Wu, Kai Zhou, Jieli Xu, Jiatian Tang, Xiyuan Han, Anqiang Wang   +13 more
wiley   +1 more source

A Giant Basal Cell Carcinoma of the Scalp-A Clinical Case Study. [PDF]

Diagnostics (Basel)
Zagórska B, Rutkowski J, Kunc M, Żółkiewicz J, Maińska U, Sobjanek M, Sławińska M.   +6 more
europepmc   +1 more source

Basal cell carcinoma preferentially arises from stem cells within hair follicle and mechanosensory niches.

Cell Stem Cell, 2015
Shelby C Peterson, M. Eberl, Alicia N. Vagnozzi, Abdelmadjid Belkadi, N. Veniaminova, M. Verhaegen, C. Bichakjian, N. Ward, A. Dlugosz, S. Y. Wong   +9 more
semanticscholar   +1 more source

Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies

Advanced Healthcare Materials, EarlyView.
Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer, Dolores J. Salander, Witold Szymanski, Johannes Graumann, Yukai Wang, Kai Zhao, Jörg W. Bartsch, María Gómez‐Serrano, Daniel Bachurski, Silke Reinartz, Elke von Pogge von Strandmann   +10 more
wiley   +1 more source