Results 211 to 220 of about 2,681,719 (261)

Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling

Advanced Science, EarlyView.
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li, Chen Wu, Yuqi Zhu, Zicheng Liu, Wenjuan Yu, Andrew Lukwaro, Yu Zhong, Guoqiang Xie, Lili Zhou, Xiaoru Huang, Hui‐yao Lan, Junzhe Chen, Ying Tang   +12 more
wiley   +1 more source

Multiple calcified basal cell carcinomas in an asymptomatic patient with a very elevated coronary calcium score. [PDF]

JAAD Case Rep
Jacobs JC, Sequeira M.
europepmc   +1 more source

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

Comprehensive Insights Into Basal Cell Carcinoma: Causes, Presentation, Prevention, and Modern Therapeutic Approaches. [PDF]

Cancer Med
Levit S, Shoykhet J, Levit E.
europepmc   +1 more source

T Cell Glycoengineering to Modulate Immune‐Tumor Crosstalk: A Universal Non‐Genetic Strategy for Enhanced Tumor Immunotherapy

Advanced Science, EarlyView.
This study describes a T cell surface engineering strategy that integrates polymer materials with tumor immunology, aiming to achieve broad‐spectrum anti‐tumor applications of glycopolymer‐engineered T (G‐T) cells via non‐genetic modification. Glycopolymer engineering generally modulates immune‐tumor crosstalk through specific cell‐cell interactions ...
Lihua Yao, He Yang, Fangjian Shan, Xiaomeng Niu, Yichen Wang, Hengyuan Zhang, Sujian Wang, Gaojian Chen, Hong Chen   +8 more
wiley   +1 more source

Global basal cell carcinoma in 55+ population: 1990- 2021 burden、risk-factor trends and 2050 forecast. [PDF]

Front Oncol
Cai YX, Rong M.
europepmc   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

The Genitourinary Pathology Society and International Society of Urological Pathology Joint Expert Consultation Recommendations on intraductal carcinoma of the prostate. [PDF]

Histopathology
Shah RB, Varma M, Zhou M, Paner GP, Amin MB, Berney DM, Cheng L, Deng FM, Downes M, Eggener S, Ehdaie B, Epstein JI, Evans A, Fine SW, Greenland N, Guo C, Han B, Hirsch MS, Izkowski KA, Kench JG, Lotan TL, Magi-Galluzzi C, Miyamoto H, Nguyen JK, Tsuzuki T, van der Kwast TH, van Leenders GJ, Williamson SR, Wobker SE, Wu CL, Yang X, Kristiansen G.   +31 more
europepmc   +1 more source

MicroRNAs as Diagnostic and Prognostic Biomarkers in Melanoma and Non-Melanoma Skin Cancers: An Updated Review. [PDF]

Diagnostics (Basel)
Oiegar A, Tigu AB, Baican A, Candrea E, Negrutiu M, Danescu S.   +5 more
europepmc   +1 more source

A Rare Constellation of Triple Cutaneous Malignancies With Sustained Therapeutic Response: Kaposi Sarcoma, Basal Cell Carcinoma, and Cutaneous Squamous Cell Carcinoma in a Single Patient. [PDF]

Cureus
Bivolarski I.
europepmc   +1 more source