Results 141 to 150 of about 105,263 (261)

MTAP Deficiency as a Metabolic Vulnerability in Cancer: Implications for Synthetic Lethal Therapy

Cancer Science, EarlyView.
MTAP deletion creates a therapeutically actionable metabolic vulnerability through MTA accumulation and PRMT5 dependency. This review summarizes the biochemical basis of MTAP‐directed synthetic lethality, emerging PRMT5/MAT2A inhibitors, clinicogenomic features of MTAP‐deleted tumors, and future strategies for precision oncology.
Hiroaki Ikushima, Hidenori Kage
wiley   +1 more source

Extracellular vesicles in nipple discharge for breast cancer screening. [PDF]

Breast Cancer Res Treat
Ozaki Y, Yoshida K, Ichikawa T, Kitagawa M, Kato M, Velaga R, Iwase M, Takano Y, Takeuchi D, Kikumori T, Murata K, Yasui T, Nagahashi M, Ebata T, Kajiyama H, Masuda N, Yokoi A.   +16 more
europepmc   +1 more source

Rare Secondary Neoplasms Arising in Epidermal Nevus: A Case Series and Literature Review

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Malignant transformation is known to occur with many nevi, such as nevus sebaceus. However, cases of secondary tumors developing in an epidermal nevus (EN) are rare, with only a few case reports documented in the literature. We present three unique cases of syringocystadenoma papilliferum (SCAP), syringofibroadenoma, trichilemmoma, and basal ...
Haya A. Homsi, Melissa Piliang, Jennifer Lucas, Jennifer S. Ko, Steven D. Billings, Shira Ronen   +5 more
wiley   +1 more source

Synchronous Lobular Breast Cancer and Lung Adenocarcinoma: Α Case Report. [PDF]

Cureus
Pantelidou V, Perdikakis E, Eleftheriadis E, Lampridis S, Tsantila I, Permekerlis A.   +5 more
europepmc   +1 more source

Gigantic invasive ductal carcinoma of the breast

The Breast Journal, 2018
Andrea P. Damin, Caren L. Pozzer, Tulio F. Farret, Andrei G. Reginatto, Eduardo N. Trindade   +4 more
openaire   +2 more sources

Multicentric Asynchronous Endocrine Mucin‐Producing Sweat Gland Carcinoma and Mucinous Carcinoma of the Skin

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Endocrine mucin‐producing sweat gland carcinoma (EMPSGC) is an adnexal neoplasm which typically occurs on periorbital skin and demonstrates overlapping histopathologic features with primary mucinous carcinoma of the skin (MCS). Herein, we report a patient who developed five distinct lesions of EMPSGC and MCS over an eight‐year period, some of ...
Ikuko Hirai, Joseph F. Sobanko, Tara C. Mitchell, Jacquelyn Roth, Rosalie Elenitsas, Emily Y. Chu   +5 more
wiley   +1 more source

Case Report: A rare triad of neoplasms: navigating synchronous accessory breast cancer, papillary thyroid carcinoma, and inflammatory nasal papilloma. [PDF]

Front Med (Lausanne)
Zeng X, Huang H, Hong Y, Meng Q, Ye K, Zhou L, Li H, Chen Y, Huang J, Feng C.   +9 more
europepmc   +1 more source

S3 guideline diagnostics and therapy in alopecia areata – Part 2: Therapy, psychosocial and cosmetic support

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary This second part of the S3 guideline on the diagnosis and treatment of alopecia areata (AA), presents key recommendations on topical and systemic therapy, quality of life and support services. The first part of the guideline, published separately, covers the definition and content of epidemiology and diagnosis as well as comorbidities, risk and
Ulrike Blume‐Peytavi, Andria Constantinou, Tsenka Tomova‐Simitchieva, Adrian Tanew, Michael Sticherling, Hermann Girschick, Annika Vogt, Uwe Schwichtenberg, Uwe Gieler, André Märtens, Kerstin Zienert, Claudia Stenders, Ricardo Niklas Werner, Doris Wilborn   +13 more
wiley   +1 more source

Case Report: response of HER2-positive ductal carcinoma <i>in situ</i> to osimertinib with supporting <i>in vitro</i> evidence. [PDF]

Front Oncol
Baba S, Koketsu M, Kuroda H, Suzuki M, Nishihara H, Kato Y, Kawami H, Harada O.   +7 more
europepmc   +1 more source

Digital exercise interventions to improve physical functioning of people with breast cancer: Protocol for a scoping review. [PDF]

PLoS One
Mankelow KA, O'Connor S, Santin O, Blackburn NE, Wilson IM.   +4 more
europepmc   +1 more source