Results 151 to 160 of about 304,742 (351)

Neuroendocrine carcinomas of the breast [PDF]

open access: yes, 2008
INTRODUCTION: Neuroendocrine (NE) breast cancers encompass a heterogeneous group of tumours showing morphological features similar to those of NE neoplasms of the gut and lung and expressing one or more neuroendocrine markers (neuron specific enolase ...
Boni, L   +7 more
core   +1 more source

[Ductal carcinoma in situ of the breast].

open access: yesIl Giornale di chirurgia, 2006
The Authors report their experience about 127 ductal carcinoma in situ (DCIS) of the breast. Guidelines for surgical treatment are: radiological or clinical diagnosis, tumor's extension, histological classification, grading and margin status. At the present the Authors prefer breast conserving surgery with tumor margin's study.
PROCACCINI, Eugenio   +6 more
openaire   +2 more sources

Cytokeratin 8 immunostaining pattern and E-cadherin expression distinguish lobular from ductal breast carcinoma.

open access: yesAmerican Journal of Clinical Pathology, 2000
Immunohistochemistry using antibodies to cytokeratin 8 can serve as a valuable diagnostic tool for the differentiation of lobular from ductal carcinomas of the breast.
H. Lehr   +4 more
semanticscholar   +1 more source

Meisoindigo Acts as a Molecular Glue to Target PKMYT1 for Degradation in Chronic Myeloid Leukemia Therapy

open access: yesAdvanced Science, EarlyView.
Meisoindigo targets PKMYT1 for degradation by acting as a molecular glue that enhances PKMYT1‐TRIM25 interaction, leading to K48‐linked ubiquitination and subsequent proteasomal degradation, thereby exerting therapeutic effects in chronic myeloid leukemia.
Zhao‐Xin Zhang   +10 more
wiley   +1 more source

Comparing VIP and PD‐L1 expression as cancer biomarkers

open access: yesImmunoMedicine, Volume 2, Issue 2, December 2022., 2022
Abstract Immune checkpoint molecules are critical targets of cancer therapies due to their ability to modulate immune responses to cancer. Vasoactive intestinal peptide (VIP) has been proposed as an immune checkpoint molecule, but its predictive and prognostic values have not been established.
Jojo Y. Liu   +6 more
wiley   +1 more source

Variable Selection with Random Survival Forest and Bayesian Additive Regression Tree for Survival Data [PDF]

open access: yesarXiv, 2019
In this paper we utilize a survival analysis methodology incorporating Bayesian additive regression trees to account for nonlinear and additive covariate effects. We compare the performance of Bayesian additive regression trees, Cox proportional hazards and random survival forests models for censored survival data, using simulation studies and survival
arxiv  

COPS5 Triggers Ferroptosis Defense by Stabilizing MK2 in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
COPS5, which is overexpressed in HCC in an amplification‐ and ATF4‐dependent manner, stabilizes MK2 through deubiquitination and, in turn, induces HSPB1 activation, protecting HCC cells from ferroptosis and thus promoting sorafenib resistance and tumor progression. Abstract Sorafenib, which is proven to serve as a potent ferroptosis inducer, is used as
Ai‐Ling Luo   +15 more
wiley   +1 more source

Granulomatous reaction associated with breast carcinoma: A report of two cases

open access: yesSaudi Journal of Medicine and Medical Sciences, 2014
The presence of a granulomatous reaction in association with a breast carcinoma is a rare phenomenon. We present two cases of breast carcinoma, invasive ductal and invasive lobular carcinoma in which a non-caseating granulomatous response was present ...
Timor Alalshee   +2 more
doaj   +1 more source

Deep learning analysis of breast MRIs for prediction of occult invasive disease in ductal carcinoma in situ [PDF]

open access: yesarXiv, 2017
Purpose: To determine whether deep learning-based algorithms applied to breast MR images can aid in the prediction of occult invasive disease following the di- agnosis of ductal carcinoma in situ (DCIS) by core needle biopsy. Material and Methods: In this institutional review board-approved study, we analyzed dynamic contrast-enhanced fat-saturated T1 ...
arxiv  

In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors. [PDF]

open access: yes, 2016
Aberrant Hedgehog (Hh)/glioma-associated oncogene (GLI) signaling has been implicated in cancer progression. Here, we analyzed GLI1, Sonic Hedgehog (Shh) and NF-κB expression in 51 breast cancer (ductal carcinoma) tissues using immunohistochemistry ...
Bei, R.   +13 more
core   +1 more source

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