Results 151 to 160 of about 162,744 (282)

Inhibition of PHF1 promotes ferroptosis via IRES‐dependent Snail translation regulation in pancreatic ductal adenocarcinoma

VIEW, EarlyView.
PHF1 is a known epigenetic regulator involved in transcriptional silencing in cancer. In this study, we identified PHF1 as an oncogene that promotes PDAC progression and demonstrated that its inhibition induces ferroptosis. Mechanistically, PHF1 physically interacts with the FBL/NOP56/NOP58 snoRNP complex to enhance the IRES‐dependent translation of ...
Yujiao Xie, Shan Jin, Yao Zhan, Tiantian Du, Yaqi Dong, Peilong Li, Xiaoshi Zhang, Qiuchen Qi, Jie Gao, Chuanxin Wang   +9 more
wiley   +1 more source

Co-existence of fibroadenoma, intraductal carcinoma and invasive ductal carcinoma in the unilateral breast mass: a case report and literature review. [PDF]

Front Oncol
Zhong S, Xu H, Ye X, Xu Y, Fan Z.
europepmc   +1 more source

miRNA Profiling of Cholesteatoma‐Derived Exosomes Reveals Exosomal miR‐223‐3p and miR‐142‐5p as Potential Biomarkers for Acquired Middle Ear Cholesteatoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Acquired cholesteatoma is an abnormal and invasive growth of keratinized squamous epithelial cells in the middle ear. The study aims to explore the role of exosomal miRNAs in the pathogenesis of acquired cholesteatoma and their potential in clinical application.
Qi Tang, Meng‐Yao Xie, Shu Wang, Zhi‐Yuan Wu, Zhi‐Jin Han, Chen Li, Shu‐Yi Wang, Yuan Cao, Yu‐Run Chen, Bin Wang, Ying‐Ying Shang, Xiao‐Wu Huang, Hua Yang   +12 more
wiley   +1 more source

Prognostic significance and regulatory role of ACOT7 in the tumor immune microenvironment of breast invasive ductal carcinoma: a multi-omics analysis. [PDF]

Front Immunol
Song C, Quan Y, Shan Y, Chen Y, Du J, Li K, Li N.   +6 more
europepmc   +1 more source

Matrix Viscoelasticity: The Overlooked Architect of Solid Tumour Evolution

Organ Medicine, EarlyView.
Ruixi Huang, Yupeng Guan
wiley   +1 more source

Endoscope‐Assisted Nipple‐Sparing Mastectomy With Immediate Implant Reconstruction: A Retrospective Study

World Journal of Surgery, EarlyView.
Breast cancer surgery increasingly favors nipple‐sparing and endoscopic techniques to optimize oncological safety, cosmetic outcomes, and patient satisfaction. We aimed to evaluate and compare the clinical efficacy and postoperative safety profiles of endoscope‐assisted and conventional open approaches for nipple‐sparing mastectomy with immediate ...
Yuan Shao, Youcheng Zhang, Huafeng Kang, Qing Zhou, Ziliang Zhang, Guiru Yan, Binghua Kan   +6 more
wiley   +1 more source

Beyond the Prostate: Incidental Detection of Male Breast Carcinoma on [¹⁸F]DCFPyl. [PDF]

J Nucl Med
Ali FZ, Gupta PK, Allen-Auerbach MS.
europepmc   +1 more source

Risk of Cancer With Hormone Replacement Therapy: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Hormone replacement therapy (HRT) remains the cornerstone of menopausal symptom management, effectively alleviating vasomotor symptoms and genitourinary syndrome, whilst mitigating long‐term risks such as osteoporosis. However, despite an increasing body of evidence on the relative safety of HRT, earlier studies that demonstrated an increased ...
Gabriella Yongue, Zachary Nash, Vikram Talaulikar, Shibani Nicum   +3 more
wiley   +1 more source

Case Report: Mixed ductal-lobular carcinoma consisting of invasive lobular carcinoma with a glycogen-rich clear cell pattern and elevated tumor mutation burden. [PDF]

Front Oncol
Kawachi K, Tang X, Kasajima R, Katayama K, Yamaguchi R, Yamaguchi K, Furukawa Y, Imoto S, Miyano S, Yoshioka E, Washimi K, Okubo Y, Sato S, Yokose T, Miyagi Y.   +14 more
europepmc   +1 more source

Preoperative Radar Localisation of Impalpable Breast and Axillary Lesions: Initial Experience in an Australian Tertiary Centre

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Introduction Image‐guided radar localisation (RL) is a wire‐free alternative to hookwire localisation (HWL) for preoperative localisation of impalpable breast and axillary lesions, with potential logistical and technical advantages. This study assesses clinical utility, accuracy of placement and surgical oncologic outcome metrics for RL using ...
Grace Carpenter, Coralie Simoni, Lucy Lu, Jacqueline Eskander, Tracy Liu, Jennifer Yuill, Sophie Nightingale, Margaret Nguyen, Joseph Paiva   +8 more
wiley   +1 more source