Results 161 to 170 of about 304,742 (351)

CCN1 Enhances Tumor Immunosuppression through Collagen‐Mediated Chemokine Secretion in Pancreatic Cancer

Advanced Science, EarlyView.
CCN1 modulates the tumor microenvironment in pancreatic cancer by promoting collagen‐dependent chemokine production, thereby facilitating immune evasion. Deletion of CCN1 not only suppresses tumor growth but also enhances immune cell infiltration and increases tumor sensitivity to both chemotherapy and immunotherapy.
Hongjie Fan, Huzi Zhao, Lili Gao, Yucheng Dong, Pei Zhang, Pengfei Yu, Yunfei Ji, Zhe‐Sheng Chen, Xinmiao Liang, Yang Chen   +9 more
wiley   +1 more source

Classifying Breast Histopathology Images with a Ductal Instance-Oriented Pipeline [PDF]

arXiv, 2020
In this study, we propose the Ductal Instance-Oriented Pipeline (DIOP) that contains a duct-level instance segmentation model, a tissue-level semantic segmentation model, and three-levels of features for diagnostic classification. Based on recent advancements in instance segmentation and the Mask R-CNN model, our duct-level segmenter tries to identify ...
arxiv  

Regulation of mammary gland branching morphogenesis by the extracellular matrix and its remodeling enzymes. [PDF]

, 2003
A considerable body of research indicates that mammary gland branching morphogenesis is dependent, in part, on the extracellular matrix (ECM), ECM-receptors, such as integrins and other ECM receptors, and ECM-degrading enzymes, including matrix ...
A Amour, A Garcia-Gasca, A Lochter, A Lochter, AC Andres, AJ D'Ardenne, AM Belkin, AR Nelson, B Lelongt, BL Hogan, BM Gumbiner, BS Wiseman, C Brisken, C Brisken, CJ Sympson, CS Atwood, CW Daniel, CW Daniel, D Alford, D Alford, DG Stupack, ED Hay, EW Thompson, F Berdichevsky, F Kheradmand, FE Jones, G Bani, G Giannelli, G Shyamala, GB Silberstein, GB Silberstein, GB Silberstein, GB Silberstein, GL Ganser, GW Robinson, GW Robinson, GW Robinson, H Birkedal-Hansen, H Joseph, HJ Hathaway, HY Ha, J Chen, J Lilla, J Muschler, J Russo, J Schlondorff, J Yant, JE Fata, JE Fata, JE Fata, JE Ferguson, JF Wiesen, JJ Wysolmerski, JJ Wysolmerski, JM Bradbury, JM Whitelock, JM Williams, JP Irigoyen, JP Lydon, JP Witty, JT Emerman, K Elenius, K Hotary, K Ito, K Morita, K Wolf, L Hennighausen, LA Rudolph-Owen, LA Rudolph-Owen, LJ van't Veer, LR Lund, M Affolter, M Durbeej, M Egeblad, M Rytomaa, M Simian, MA Arnaout, MD Infeld, MD Sternlicht, MF Horster, MH Barcellos-Hoff, MJ van de Vijver, MM Zutter, MM Zutter, MP Osborne, MR Crowley, MR Warner, MS Wicha, N Koshikawa, N Quarto, NJ Kenney, NK Wessells, OW Petersen, P Bashkin, PR Warfield, PY Desprez, R Lagace, RH Wetzels, RS Talhouk, S Coleman, S Mukherjee, S Selvarajan, S Sinha, S Stahl, SD Banerjee, SD Robinson, SE Baker, SH Barsky, SL Bullock, SM Ellerbroek, T Darribere, T Gudjonsson, T Hayakawa, T Hayakawa, T Hayakawa, TC Klinowska, TC Klinowska, TC Klinowska, TH Vu, TN Seagroves, U Felbor, V Gouon-Evans, V Noe, VM Weaver, W Ruan, W Wang, W Xie, WF Vogel, WF Vogel, WH Yu, WP Bocchinfuso, Y Fukuda, Y Fukuda, Y Hirai, Y Hirai, Y Kadono, Y Nakanishi, YS Kanwar, Z Werb, Z Zhu   +139 more
core   +2 more sources

Plasma DNMT1 Activity for Assessing Tumor Burden and Predicting Neoadjuvant Therapy Response in Breast Cancer

Advanced Science, EarlyView.
In this work, a detection method is presented for the activity of plasma DNA methyltransferase 1 (DNMT1), namely DNMT1 Identification by Variable Activity (DIVA). DIVA can detect plasma DNMT1 at levels as low as 10−7 U mL−1, also it successfully evaluated tumor burden and predicted the neoadjuvant therapy responses of breast cancer patients.
Yingran Wang, Guozhi Zhang, Zhizhao Zhang, Mengsi Zhang, Jiao Chen, Ke Wang, Lu Liu, Jing Bao, Ming Chen, Xiaowei Qi, Mingxuan Gao   +10 more
wiley   +1 more source

Rare case of male breast intraductal papilloma progressing to invasive ductal carcinoma: A radiologic-pathologic correlation

Radiology Case Reports, 2018
Although male breast cancer represents only 0.5%-1% of all breast cancer cases in the United States, the incidence of this disease is slowly rising [1]. Because of its extremely low prevalence, screening and treatment guidelines are not well established.
Gaurav Anand, BLA, Nabil Al-Khalisi, MD, MPH, Dauod Arif, MD, Soheila Hamidpour, MD, Tiffany Lewis, DO, MBA   +4 more
doaj  

Neuroendocrine Carcinoma of the Breast – Real versus Mimic [PDF]

Journal of Krishna Institute of Medical Sciences University, 2016
Primary neuroendocrine carcinoma of the breast is a rare entity and is difcult to differentiate from invasive ductal carcinoma with neuroendocrine differentiation especially on small core biopsy specimens.
Megha Joshi, Lucy H. Kapur, Clarence Owens, Monika Roychowdhury, Ananya Kaul   +4 more
doaj  

Thyroid transcription factor-1 positive primary breast cancer: a case report with review of the literature

Diagnostic Pathology, 2010
This case describes an infiltrating breast tumour with thyroid transcription factor-1 (TTF-1) positive staining and ductal differentiation in a 72-year-old woman.
Westre Bjørn, Aas Hans, Gundersen Marian D, Chen Ying, Klingen Tor A, Sauer Torill   +5 more
doaj   +1 more source

INVESTIGATING INVASION IN DUCTAL CARCINOMA IN SITU WITH TOPOGRAPHICAL SINGLE CELL GENOME SEQUENCING [PDF]

, 2018
Synchronous Ductal Carcinoma in situ (DCIS-IDC) is an early stage breast cancer invasion in which it is possible to delineate genomic evolution during invasion because of the presence of both in situ and invasive regions within the same sample.
Casasent, Anna, Casasent, Anna
core   +1 more source

CXCL6 Reshapes Lipid Metabolism and Induces Neutrophil Extracellular Trap Formation in Cholangiocarcinoma Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
CXCL6's function in cholangiocarcinoma is underexplored. Here it is discovered that CXCL6 is upregulated in cholangiocarcinoma tissues and promotes proliferation and metastasis of it. CXCL6 functions through the CXCR1/2‐JAK‐STAT/PI3K axis and reshaping tumor lipid metabolism.
Tian He, Zi‐Yi Wang, Bin Xu, Cheng‐Jie Zhong, Lu‐Na Wang, Huan‐Chen Shi, Zi‐Yue Yang, Shi‐Qi Zhou, Hui Li, Bo Hu, Xiao‐Dong Zhu, Ying‐Hao Shen, Jian Zhou, Jia Fan, Hui‐Chuan Sun, Cheng Huang   +15 more
wiley   +1 more source

Mixed Mucinous and Invasive Ductal Carcinoma of Male Breast: A Rare Case Report [PDF]

Male breast carcinoma is a rare entity. Here, we present a case of mixed mucinous carcinoma i.e. composite mucinous carcinoma with infiltrating ductal carcinoma component in a 55 year old man. Patient clinically presented with a lump in his right breast.
Kuldeep Ananda Vaidhya
core   +1 more source