Results 241 to 250 of about 825,494 (348)

Machine learning using entropy-based texture features from MRI to differentiate histological subtypes of non-small cell lung cancer identified as metabolically active on PET/MRI. [PDF]

PLoS One
Borowska M, Mojsak M, Bębas E, Pauk J, Hładuński M, Domino M.   +5 more
europepmc   +1 more source

Locally Advanced Lung Non-Small Cell Carcinoma [PDF]

, 2020
openaire   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source

Rare Combined Small-Cell Lung Carcinoma With Lymph Node Metastasis Exclusive to the Small-Cell Component: A Case Report. [PDF]

Cureus
Bendadi S, El Karnighi O, El Ouazzani M, Rais H, Belbaraka R.   +4 more
europepmc   +1 more source

Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition.

Cancer Research, 2005
S. Thomson, E. Buck, F. Petti, Graeme Griffin, E. Brown, Nishal Ramnarine, K. Iwata, N. Gibson, J. Haley   +8 more
semanticscholar   +1 more source

ACSL5 Regulates Glucose Metabolism and Chemotherapy Sensitivity in Colorectal Cancer Cells under Glutamine Deficiency

Advanced Science, EarlyView.
Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian, Qiaoxia Zhang, Xuedan Sun, Rick Francis Thorne, Zeyuan Shi, Qiang Ji, Zhangran Sun, Yuanxiang Lu, Qun Zhao, Xianjun Yu, Wanglai Hu, Mian Wu   +11 more
wiley   +1 more source

First Report of Entrectinib as a Treatment Option for Pure Squamous Cell Carcinoma Harboring <i>ROS1</i> Rearrangement: Exploring the Role of Next-Generation Sequencing in Targeted Therapy. [PDF]

Int J Mol Sci
Tang YJ, Chen RH, Lu YS, Wu CE.
europepmc   +1 more source

American Society of Clinical Oncology treatment of unresectable non-small-cell lung cancer guideline: update 2003.

Journal of Clinical Oncology, 2004
D. Pfister, David H. Johnson, C. Azzoli, W. Sause, Thomas J. Smith, Sherman Baker, J. Olak, D. Stover, John R. Strawn, A. Turrisi, M. Somerfield   +10 more
semanticscholar   +1 more source

Characterizing Stage‐Specific Cellular Dynamics and Microenvironmental Remodeling in Lung Adenocarcinoma by Single‐Cell RNA Sequencing

Advanced Science, EarlyView.
This study integrated early‐stage patient specimens with publicly available datasets encompassing non‐malignant lung tissues and advanced‐stage LUAD through single‐cell sequencing, revealing a dynamically remodeled tumor microenvironment characterized by a hypoxia‐adapted malignant subset (C5), immunosuppressive LGMN+ macrophages, STAT1‐driven ...
Bomiao Qing, Xiaolan Li, Xiang He, Junyi Wang, Yi Yang, Manling Jiang, Bingbing Yan, Lei Zhang, Anying Xiong, Qin Ran, Guoping Li   +10 more
wiley   +1 more source

Lymph Node Metastasis and Recurrence Patterns in Clinical Stage IA Lower-Lobe Non-Small Cell Lung Cancer: Toward an Optimal Surgical Strategy for Superior Segment (S6) Tumors. [PDF]

Ann Thorac Cardiovasc Surg
Suzuki S, Matsubayashi Y, Sato K, Noritake O, Matsui T, Seto K, Sakakura N.   +6 more
europepmc   +1 more source