Prognostic factors of survival in patients with lung cancer after low-dose computed tomography screening: a multivariate analysis of a lung cancer screening cohort in China. [PDF]
Li J+5 more
europepmc +1 more source
Multimodality Treatment for Non-small-cell Lung Carcinoma
Scott J. Swanson, Todd S. Weiser
openaire +2 more sources
This study develops TMEclassifier, a machine‐learning tool that classifies cancers into three distinct subtypes—Immune exclusive (IE), immune suppressive (IS), and immune activated (IA)—which exhibit significant heterogeneity and necessitate customized therapeutic strategies.
Dongqiang Zeng+27 more
wiley +1 more source
Single-arm phase II study of consolidation serplulimab following hypofractionated radiotherapy with concurrent chemotherapy for patients with limited stage small-cell lung cancer: ASTRUM-LC01 study protocol. [PDF]
Wu Y+7 more
europepmc +1 more source
A quantitative CTC RNA assay is developed by incorporating multi‐antibody‐based CTC isolation and specific mRNA quantification using RT‐ddPCR. The NSCLC CTC ScoreD demonstrates high accuracy for early‐stage NSCLC detection, significantly outperforming serum CEA. NSCLC CTC ScoreM exhibits a more accurate early‐warning of responses to different therapies
Xiaoyu Wang+14 more
wiley +1 more source
Comparison of clinicopathologic features and prognosis between surgically resected pulmonary large-cell neuroendocrine carcinoma and small-cell lung cancer. [PDF]
Mao Y+11 more
europepmc +1 more source
This study uses single‐nucleus RNA sequencing and spatial transcriptomics to investigate penile squamous cell carcinoma (PSCC). It reveals that PSCC tumor cells mimic normal penile epithelium differentiation, independent of HPV status. The Tum_1 subtype shows basal stem‐like characteristics and promotes invasiveness. HPV‐positive basal stem‐like tumors
Hongjian Song+37 more
wiley +1 more source
Chylothorax as the Initial Manifestation of Small Cell Lung Carcinoma. [PDF]
Krishnan S+2 more
europepmc +1 more source
SMC4 Promotes Prostate Cancer Cell Proliferation and Metastasis via the Rheb/mTOR Pathway
Structural maintenance of chromosome protein 4 (SMC4) has been implicated in prostate cancer metastasis. Knockdown of SMC4 in RM1‐LM cells significantly attenuates proliferation, migration, and lung metastasis in vivo. Furthermore, SMC4 interacts with GLUT1 (Slc2a1), thereby enhancing glycolysis, ATP production, and activation of the Rheb/mTOR pathway.
Wei Zhang+9 more
wiley +1 more source
Statement of Retraction: LncRNA SNHG12 in extracellular vesicles derived from carcinoma-associated fibroblasts promotes cisplatin resistance in non-small cell lung cancer cells. [PDF]
europepmc +1 more source