Results 291 to 300 of about 825,494 (348)

Irradiated Tumor Cell‐Derived Microparticles Activate Systemic Anti‐Tumor Immunity via the STING/NLRP3/GSDMD Axis in Neutrophils

Advanced Science, EarlyView.
Radiotherapy induces tumor cells to release microparticles (RT‐MPs) into the circulation. The mitochondrial DNA carried by these RT‐MPs activates the STING/NLRP3/GSDMD axis in splenic neutrophils, triggering IL‐1β secretion. This, in turn, enhances dendritic cell function and facilitates the formation of cytotoxic T lymphocytes, thereby promoting ...
Yan Hu, Jiacheng Wang, Mengjie Che, Zheng Yang, Jingshu Meng, Xiao Yang, Yue Deng, Zhiyuan Zhou, Yijun Wang, Wenwen Wei, Zhanjie Zhang, Bian Wu, You Qin, Kunyu Yang, Honglin Jin, Fang Huang, Yajie Sun, Lu Wen, Chao Wan   +18 more
wiley   +1 more source

Is pneumonectomy still relevant for non-small cell lung cancer? Long-term overall survival from a 15-year experience. [PDF]

Can J Surg
Hache PL, Galvaing G, Simard S, Couture EJ, Sassi S, Champagne C, Conti M, Gregoire J, Laliberté AS.   +8 more
europepmc   +1 more source

A20 Facilitates Oxaliplatin Sensitivity in Colorectal Cancer Through Monoubiquitylation of IKK‐β

Advanced Science, EarlyView.
This study demonstrates that the expression of A20, a ubiquitin‐editing enzyme, is positively correlated with oxaliplatin sensitivity in colorectal cancer (CRC). Mechanistically, A20 enhances oxaliplatin sensitivity by inhibiting NF‐κB nuclear translocation through monoubiquitination of IKK‐β.
Fan Luo, Ting Yang, Jiaxin Cao, Qun Chen, Zhenhai Lu, Feiteng Lu, Chaozhuo Lin, Zengfei Xia, Yuanzhong Yang, Peng Li, Wenjuan Ma, Min Luo, Rongxin Zhang   +12 more
wiley   +1 more source

Case Report: Analysis of colposcopic image features in a case of early-stage small cell neuroendocrine carcinoma of the cervix. [PDF]

Front Oncol
Yuan L, Liu K.
europepmc   +1 more source

Cancer‐Like Fragmentomic Characteristics of Somatic Variants in Cell‐Free DNA

Advanced Science, EarlyView.
We report that in non‐cancerous subjects, cell‐free (cfDNA) molecules harboring somatic variants exhibit cancer‐like fragmentomic characteristics associated with clonal hematopoiesis. Importantly, these somatic variant‐associated fragmentomic aberrations are more pronounced in cancer patients. Leveraging such somatic variant‐associated signals in cfDNA,
Zhenyu Zhang, Yunyun An, Mengqi Yang, Yuqi Pan, Xiaoyi Liu, Fanglei Gong, Huizhen Lin, Bianbian Tang, Yunxia Bai, Xin Zhao, Yu Zhao, Changzheng Du, Kun Sun   +12 more
wiley   +1 more source

<i>Asparagine synthetase (ASNS)</i> Drives Tumorigenicity in Small Cell Lung Cancer. [PDF]

Biomedicines
Jeong M, Kim BC, Choi HJ, Lee GT, Jang SM, Kim KB.   +5 more
europepmc   +1 more source

Artificial Intelligence in Oncologic Thoracic Surgery: Clinical Decision Support and Emerging Applications. [PDF]

Cancers (Basel)
Petrella F, Rizzo S.
europepmc   +1 more source

Understanding Non-Small-Cell Lung Cancer: Biology, Therapeutics and Drug Resistance. [PDF]

Biomedicines
Ahluwalia P, Kolhe R, Rojiani M.
europepmc   +1 more source

Mixed Adenoneuroendocrine carcinoma of uterine cervix: a case series and review of literature. [PDF]

Oxf Med Case Reports
Salehiazar S, Baboli KM, Lebby E, McPhaul L.   +3 more
europepmc   +1 more source