Results 91 to 100 of about 152,669 (311)

Controversies in the efficacy of adjuvant chemotherapy in different epithelial ovarian carcinoma histologies

open access: yesJournal of Oncological Sciences, 2019
Aim: In this retrospective study, the efficacy of adjuvant chemotherapy and its contribution to prognosis were investigated in patients diagnosed with different subgroups of ovarian carcinoma at stages 1–3.
Ece Esin   +5 more
doaj   +1 more source

NET‐DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy‐Mediated Anoikis Resistance in Endometriosis

open access: yesAdvanced Science, EarlyView.
NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang   +12 more
wiley   +1 more source

Investigating the potential for expediting diagnosis of ovarian cancer via prompt symptom recognition & "targeted screening"

open access: yes, 2009
PhDThis thesis explores the potential for using symptoms as a tool to bring forward the diagnosis of ovarian cancer. Current evidence supports the existence of prediagnostic symptoms, however symptom lead time has yet to be adequately quantified ...
Lim, Anita Wey Wey
core  

High Mesothelin Correlates with Chemoresistance and Poor Survival in Epithelial Ovarian Carcinoma

open access: yes, 2009
The objective of this paper is to investigate the mesothelin expression level to the clinicopathological features, chemoresponse, and to the outcome of patients with epithelial ovarian carcinoma (EOC).
C-Y Hsieh   +9 more
core   +1 more source

Progesterone reduces cell survival in primary cultures of endometrioid ovarian cancer

open access: yesJournal of Ovarian Research, 2019
Background Ovarian cancer is the most lethal of all gynecologic malignancies. The relationship between sexual steroids receptors and ovarian cancer progression has been largely evaluated. The presence of progesterone receptors has been associated with an
Enrique Pedernera   +4 more
doaj   +1 more source

ABHD17C‐Mediated S‐Depalmitoylation of BCL6B Enhances CD24 Transcription to Resist Macrophage Phagocytosis in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang   +9 more
wiley   +1 more source

Overexpression of Her-2/Neu in Epithelial Ovarian Carcinoma Induces Vascular Endothelial Growth Factor C by Activating Nf-Kappa B: Implications for Malignant Ascites Formation and Tumor Lymphangiogenesis

open access: yes, 2009
Vascular endothelial growth factor C (VEGF-C) is an important growth factor that governs lymphatic spread and the development of intraperitoneal tumors associated with epithelial ovarian cancer; however, its regulation is not yet understood ...
謝長堯;陳祈安;周佳宏;鄭永銘;郭明良;魏凌鴻   +1 more
core  

Downregulation of INPP4B is Associated with Poor Prognosis in Epithelial Ovarian Carcinoma

open access: yesInternational Journal of General Medicine
Liangliang Jiang, Jing Wang Department of Gynecological Tumor, Harbin Medical University Cancer Hospital, Harbin, People’s Republic of ChinaCorrespondence: Jing Wang, Department of Gynecological Tumor, Harbin Medical University Cancer Hospital, Harbin ...
Jiang L, Wang J
doaj  

The Characteristics of Sociodemography, Histopathologic Features, Stage, and Management of Ovarian Cancer in Dr. Ramelan Navy Hospital Surabaya

open access: yesIndonesian Journal of Cancer
Background: Ovarian cancer is considered a silent killer disease, mainly due to the late diagnosis. It is often diagnosed at an advanced stage, thus increasing the mortality rate.
Karina Rahmalia   +3 more
doaj   +1 more source

Clinical implication for endometriosis associated with ovarian cancer

open access: yesGynecology and Minimally Invasive Therapy, 2017
We reviewed current literature regarding the association of endometriosis and epithelial ovarian cancer based on epidemiology studies, molecular researches and clinical observations. Our methods include a review of literature research of MEDLINE, PubMed,
Pao-Ling Torng
doaj   +1 more source

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