Results 1 to 10 of about 235,116 (346)

Collision of ductal adenocarcinoma and neuroendocrine tumor of the pancreas: a case report and review of the literature [PDF]

World Journal of Surgical Oncology, 2017
Background Simultaneous occurrence of exocrine and neuroendocrine tumors of the pancreas is very infrequent. We report a patient with an endocrine tumor in the pancreatic-duodenal area and extensive exocrine carcinoma involving the whole pancreas.
Simone Serafini, Gianfranco Da Dalt, Gioia Pozza, Stella Blandamura, Michele Valmasoni, Stefano Merigliano, Cosimo Sperti   +6 more
doaj   +4 more sources

Loss of Brg1 and Pten in Pancreatic Ductal Cells Forms Intraductal Tubulopapillary Neoplasm via the YAP/TAZ PathwaySummary [PDF]

Cellular and Molecular Gastroenterology and Hepatology
Background & Aims: Intraductal tubulopapillary neoplasm (ITPN) is a rare, high-grade tumor of the pancreatic duct, characterized by distinct molecular features including frequent alterations in the components of switch/sucrose nonfermenting (SWI/SNF)
Kei Iimori, Akihisa Fukuda, Munemasa Nagao, Sho Matsuyama, Munehiro Ikeda, Yoko Masui, Shinnosuke Nakayama, Naoki Aoyama, Kenta Mizukoshi, Munenori Kawai, Go Yamakawa, Kosuke Iwane, Mayuki Omatsu, Yu Muta, Takahisa Maruno, Kosuke Minaga, Katsutoshi Kuriyama, Shujiro Yazumi, Osamu Araki, Yuki Yamauchi, Takayuki Anazawa, Kazuyuki Nagai, Jorge Ferrer, Yuki Nakanishi, Tatsuaki Tsuruyama, Etsuro Hatano, Hiroshi Seno   +26 more
doaj   +2 more sources

Pancreatic ductal adenocarcinoma concomitant with pancreatic metastases of clear-cell renal cell carcinoma: a case report

Journal of Medical Case Reports, 2021
Background Metastatic spread to the pancreas is a rare event. Renal cell carcinoma represents one possible site of origin of pancreatic metastases. Renal cell carcinoma often metastasizes late and exclusively to the pancreas, suggesting a special role of
Lena Haeberle, Melanie Busch, Julian Kirchner, Georg Fluegen, Gerald Antoch, Wolfram Trudo Knoefel, Irene Esposito   +6 more
doaj   +1 more source

Current Status of the Diagnosis of Early-Stage Pancreatic Ductal Adenocarcinoma

Diagnostics, 2023
Pancreatic ductal adenocarcinoma (PDAC) can be treated with surgery, chemotherapy, and radiotherapy. Despite medical progress in each field in recent years, it is still insufficient for managing PDAC, and at present, the only curative treatment is ...
Kazunori Nakaoka, E. Ohno, Naoto Kawabe, T. Kuzuya, K. Funasaka, Y. Nakagawa, M. Nagasaka, T. Ishikawa, Ayako Watanabe, T. Tochio, R. Miyahara, Tomoyuki Shibata, H. Kawashima, Senju Hashimoto, Yoshiki Hirooka   +14 more
semanticscholar   +1 more source

Cancer Stem Cells in Pancreatic Ductal Adenocarcinoma

International Journal of Molecular Sciences, 2023
The first discovery of cancer stem cells (CSCs) in leukaemia triggered active research on stemness in neoplastic tissues. CSCs represent a subpopulation of malignant cells, defined by unique properties: a dedifferentiated state, self-renewal ...
Roman Bubin, Romans Uljanovs, Ilze Strumfa   +2 more
semanticscholar   +1 more source

Comprehensive review of pancreatic acinar cell carcinoma: epidemiology, diagnosis, molecular features and treatment

Japanese Journal of Clinical Oncology, 2023
Pancreatic acinar cell carcinoma is a rare form (0.2–4.3%) of pancreatic neoplasm with unique clinical and molecular characteristics, which largely differ from pancreatic ductal adenocarcinoma.
K. Ikezawa, M. Urabe, Yugo Kai, R. Takada, Hirofumi Akita, S. Nagata, K. Ohkawa   +6 more
semanticscholar   +1 more source

Molecular drivers and cells of origin in pancreatic ductal adenocarcinoma and pancreatic neuroendocrine carcinoma

Experimental Hematology & Oncology, 2020
Pancreatic cancer is one of the most common causes of cancer-related deaths worldwide. The two major histological subtypes of pancreatic cancer are pancreatic ductal adenocarcinoma (PDAC), accounting for 90% of all cases, and pancreatic neuroendocrine ...
Heli Gao, Wen-quan Wang, Xianjun Yu, Liang Liu   +3 more
semanticscholar   +1 more source

Computed Tomography-Based Radiomics Signature for the Preoperative Differentiation of Pancreatic Adenosquamous Carcinoma From Pancreatic Ductal Adenocarcinoma

Frontiers in Oncology, 2020
Purpose The purpose was to assess the predictive ability of computed tomography (CT)-based radiomics signature in differential diagnosis between pancreatic adenosquamous carcinoma (PASC) and pancreatic ductal adenocarcinoma (PDAC).
S. Ren, R. Zhao, Wenjing Cui, Wenli Qiu, Kai Guo, Yingying Cao, S. Duan, Zhongqiu Wang, Rong Chen   +8 more
semanticscholar   +1 more source

Single-cell transcriptomics reveals heterogeneous progression and EGFR activation in pancreatic adenosquamous carcinoma

International Journal on Biological Sciences, 2021
Pancreatic adenosquamous carcinoma (PASC) — a rare pathological pancreatic cancer (PC) type — has a poor prognosis due to high malignancy. To examine the heterogeneity of PASC, we performed single-cell RNA sequencing (scRNA-seq) profiling with sample ...
Xin Zhao, Han Li, Shaocheng Lyu, Jialei Zhai, Zhiwei Ji, Zhigang Zhang, Xinxue Zhang, Zhe Liu, Huaguang Wang, Junming Xu, H. Fan, J. Kou, Li-xin Li, R. Lang, Qiang He   +14 more
semanticscholar   +1 more source

Contribution of galectin-1, a glycan-binding protein, to gastrointestinal tumor progression [PDF]

, 2017
Gastrointestinal cancer is a group of tumors that affect multiple sites of the digestive system, including the stomach, liver, colon and pancreas. These cancers are very aggressive and rapidly metastasize, thus identifying effective targets is crucial ...
Bacigalupo, Maria Lorena, Carabias, Pablo, Troncoso, María Fernanda   +2 more
core   +1 more source