Molecular drivers and cells of origin in pancreatic ductal adenocarcinoma and pancreatic neuroendocrine carcinoma [PDF]
Experimental Hematology & Oncology, 2020 Pancreatic cancer is one of the most common causes of cancer-related deaths worldwide. The two major histological subtypes of pancreatic cancer are pancreatic ductal adenocarcinoma (PDAC), accounting for 90% of all cases, and pancreatic neuroendocrine ...
H. Gao +3 more
semanticscholar +5 more sources
Repeated Pancreatectomy for Recurrent Pancreatic Carcinoma after Pylorus-Preserving Pancreatoduodenectomy: Report of Two Patients [PDF]
Case Reports in Gastroenterology, 2010 Repeated pancreatectomy for pancreatic carcinoma is extremely rare. We report two such patients who underwent pancreatectomy for carcinoma developing in the pancreatic remnant after pylorus-preserving pancreatoduodenectomy (PpPD) for invasive pancreatic ...
Toshitatsu Ogino +7 more
doaj +4 more sources
Collision of ductal adenocarcinoma and neuroendocrine tumor of the pancreas: a case report and review of the literature [PDF]
World Journal of Surgical Oncology, 2017 Background Simultaneous occurrence of exocrine and neuroendocrine tumors of the pancreas is very infrequent. We report a patient with an endocrine tumor in the pancreatic-duodenal area and extensive exocrine carcinoma involving the whole pancreas.
Simone Serafini +6 more
doaj +4 more sources
Expression of matrix metalloproteinase 9 in pancreatic ductal carcinoma is associated with tumor metastasis formation. [PDF]
Folia Histochemica et Cytobiologica, 2007 The objective of the current study was to assess the expression of matrix metalloproteinase 9 (MMP-9) in pancreatic ductal carcinoma and to examine its correlation with chosen clinico-anatomical parameters.
Andrzej Kemona +4 more
doaj +3 more sources
Experimental trial for diagnosis of pancreatic ductal carcinoma based on gene expression profiles of pancreatic ductal cells [PDF]
Cancer Science, 2005 Pancreatic ductal carcinoma (PDC) remains one of the most intractable human malignancies, mainly because of the lack of sensitive detection methods. Although gene expression profiling by DNA microarray analysis is a promising tool for the development of such detection systems, a simple comparison of pancreatic tissues may yield misleading data that ...
Madoka Ishikawa +12 more
semanticscholar +4 more sources
Acinar cell carcinoma of the pancreas: can CT and MR features predict survival? [PDF]
Cancer ImagingObjective To evaluate the CT and MRI features of pancreatic acinar cell carcinoma (pACC) and their association with patient outcome and survival. Methods This retrospective single-center study included 49 patients with pathology-proven pancreatic acinar ...
Monica Cheng +5 more
doaj +2 more sources
Screening of genes specifically activated in the pancreatic juice ductal cells from the patients with pancreatic ductal carcinoma [PDF]
Cancer Science, 2003 Pancreatic ductal carcinoma (PDC) is one of the most intractable human malignancies. Surgical resection of PDC at curable stages is hampered by a lack of sensitive and reliable detection methods. Given that DNA microarray analysis allows the expression of thousands of genes to be monitored simultaneously, it offers a potentially suitable approach to ...
Koji Yoshida +14 more
semanticscholar +3 more sources
Loss of TRAIL-receptors is a recurrent feature in pancreatic cancer and determines the prognosis of patients with no nodal metastasis after surgery. [PDF]
, 2013 Agonistic antibodies targeting TRAIL-receptors 1 and 2 (TRAIL-R1 and TRAIL-R2) are being developed as a novel therapeutic approach in cancer therapy including pancreatic cancer.
Bader, Dominik C. +8 more
core +15 more sources
Ca2+ Signaling and Its Potential Targeting in Pancreatic Ductal Carcinoma [PDF]
Cancers, 2021 Pancreatic cancer (PC) is a major cause of cancer-associated mortality in Western countries (and estimated to be the second cause of cancer deaths by 2030). The main form of PC is pancreatic adenocarcinoma, which is the fourth most common cause of cancer-related death, and this situation has remained virtually unchanged for several decades.
Bettaieb, Louay +20 more
openaire +5 more sources
Journal of Medical Case Reports, 2021 Background Metastatic spread to the pancreas is a rare event. Renal cell carcinoma represents one possible site of origin of pancreatic metastases. Renal cell carcinoma often metastasizes late and exclusively to the pancreas, suggesting a special role of
Lena Haeberle +6 more
doaj +1 more source