Results 41 to 50 of about 64,621 (307)

Screening of genes specifically activated in the pancreatic juice ductal cells from the patients with pancreatic ductal carcinoma [PDF]

Cancer Science, 2003
Pancreatic ductal carcinoma (PDC) is one of the most intractable human malignancies. Surgical resection of PDC at curable stages is hampered by a lack of sensitive and reliable detection methods. Given that DNA microarray analysis allows the expression of thousands of genes to be monitored simultaneously, it offers a potentially suitable approach to ...
Koji, Yoshida, Shuichi, Ueno, Toshiyasu, Iwao, Souichirou, Yamasaki, Akira, Tsuchida, Ken, Ohmine, Ruri, Ohki, Young Lim, Choi, Koji, Koinuma, Tomoaki, Wada, Jun, Ota, Yoshihiro, Yamashita, Kazuaki, Chayama, Kazuhiro, Sato, Hiroyuki, Mano   +14 more
openaire   +2 more sources

Recent Developments in the Treatment of Pancreatic Cancer

Acta Médica Portuguesa, 2023
Pancreatic duct adenocarcinoma is currently the sixth-leading cause of cancer death worldwide and the fourth in Europe, with a continuous increase in annual lethality in Portugal during the last two decades.
Jorge Paulino, Hélder Mansinho
doaj   +1 more source

Experimental trial for diagnosis of pancreatic ductal carcinoma based on gene expression profiles of pancreatic ductal cells [PDF]

Cancer Science, 2005
Pancreatic ductal carcinoma (PDC) remains one of the most intractable human malignancies, mainly because of the lack of sensitive detection methods. Although gene expression profiling by DNA microarray analysis is a promising tool for the development of such detection systems, a simple comparison of pancreatic tissues may yield misleading data that ...
Madoka, Ishikawa, Koji, Yoshida, Yoshihiro, Yamashita, Jun, Ota, Shuji, Takada, Hiroyuki, Kisanuki, Koji, Koinuma, Young Lim, Choi, Ruri, Kaneda, Toshiyasu, Iwao, Kiichi, Tamada, Kentaro, Sugano, Hiroyuki, Mano   +12 more
openaire   +2 more sources

Pancreatic resections for advanced M1-pancreatic carcinoma : the value of synchronous metastasectomy

, 2010
Background: For M1 pancreatic adenocarcinomas pancreatic resection is usually not indicated. However, in highly selected patients synchronous metastasectomy may be appropriate together with pancreatic resection when operative morbidity is low ...
Chromik, Ansgar Michael, M. H. Seelig, A. M. Chromik, Tannapfel, Andrea, Seelig, Mathias H., S. K. Seelig, Seelig, Stefanie Katharina, Burkert, Björn, Uhl, Waldemar, A. Tannapfel, B. Burkert, W. Uhl   +11 more
core   +1 more source

Molecular drivers and cells of origin in pancreatic ductal adenocarcinoma and pancreatic neuroendocrine carcinoma [PDF]

Experimental Hematology & Oncology, 2020
AbstractPancreatic cancer is one of the most common causes of cancer-related deaths worldwide. The two major histological subtypes of pancreatic cancer are pancreatic ductal adenocarcinoma (PDAC), accounting for 90% of all cases, and pancreatic neuroendocrine neoplasm (PanNEN), which makes up 3–5% of all cases.
He-Li Gao, Wen-Quan Wang, Xian-Jun Yu, Liang Liu   +3 more
openaire   +3 more sources

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

Hepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu, Bingqing Xu, Xiaodong Wang, Wen‐Hua Wan, Jinying Lu, Deyuan Kong, Yu Jin, Wenhua You, Hua Sun, Xiaoxin Mu, Dongju Feng, Yun Chen   +11 more
wiley   +1 more source

The role of radiotherapy in multimodal treatment of pancreatic carcinoma

Radiation Oncology, 2010
Pancreatic ductal carcinoma is one of the most lethal malignancies, but in recent years a number of positive developments have occurred in the management of pancreatic carcinoma.
Scott-Brown Martin, Brunner Thomas B
doaj   +1 more source

Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma

Hepatology, EarlyView., 2022
Steatotic HCC can be diagnosed by MRI and forms a pro‐tumor immune microenvironment with high expression of PD‐L1, M2 polarization of macrophages and activation of CAFs, which may be a good target for combined immunotherapy. Abstract Background and Aims Immunotherapy has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC), but its ...
Hiroki Murai, Takahiro Kodama, Kazuki Maesaka, Shoichiro Tange, Daisuke Motooka, Yutaka Suzuki, Yasuyuki Shigematsu, Kentaro Inamura, Yoshihiro Mise, Akio Saiura, Yoshihiro Ono, Yu Takahashi, Yota Kawasaki, Satoshi Iino, Shogo Kobayashi, Masashi Idogawa, Takashi Tokino, Tomomi Hashidate‐Yoshida, Hideo Shindou, Masanori Miyazaki, Yasuharu Imai, Satoshi Tanaka, Eiji Mita, Kazuyoshi Ohkawa, Hayato Hikita, Ryotaro Sakamori, Tomohide Tatsumi, Hidetoshi Eguchi, Eiichi Morii, Tetsuo Takehara   +29 more
wiley   +1 more source

Cost-effectiveness of diagnostic laparoscopy for assessing resectability in pancreatic and periampullary cancer.

, 2015
Surgical resection is the only curative treatment for pancreatic and periampullary cancer, but many patients undergo unnecessary laparotomy because tumours can be understaged by computerised tomography (CT).
Morris, S, Gurusamy, KS, Davidson, BR, Kurinchi S Gurusamy, Stephen Morris, Sheringham, J, Brian R Davidson, Jessica Sheringham   +7 more
core   +1 more source

Cancer Stem Cells in Pancreatic Ductal Adenocarcinoma [PDF]

, 2023
The first discovery of cancer stem cells (CSCs) in leukaemia triggered active research on stemness in neoplastic tissues. CSCs represent a subpopulation of malignant cells, defined by unique properties: a dedifferentiated state, self-renewal ...
Bubin, Roman, Strumfa, Ilze, Romans Uljanovs, Roman Bubin, Uljanovs, Romans, Ilze Strumfa   +5 more
core   +1 more source