Results 61 to 70 of about 64,621 (307)

Molecular mechanisms of drug resistance, invasion and metastasis in pancreatic carcinoma [PDF]

, 2008
The research outlined in this thesis aims to further our knowledge of the biological characteristics underlying the aggressive behaviour by which pancreatic cancer invades and metastasises at an early stage and is refractory to most chemotherapeutic ...
Walsh, Naomi
core  

Coumarin-Palladium(II) Complex Acts as a Potent and Non-Toxic Anticancer Agent against Pancreatic Carcinoma Cells

Molecules, 2022
Pancreatic carcinoma still represents one of the most lethal malignant diseases in the world although some progress has been made in treating the disease in the past decades.
Aleksandra Krstic, Aleksandar Pavic, Edina Avdovic, Zoran Markovic, Milena Stevanovic, Isidora Petrovic   +5 more
doaj   +1 more source

PACAP and PAC1 receptor expression in pancreatic ductal carcinoma

Oncology Letters, 2019
Pancreatic carcinoma is one of the most malignant diseases and is associated with a poor survival rate. Pituitary adenylate cyclase activating polypeptide (PACAP) is a neuropeptide that acts on three different G protein-coupled receptors: the specific PAC1 and the VPAC1/2 that also bind vasoactive intestinal peptide.
Ferencz, Sandor, Reglodi, Dora, Kaszas, Balint, Bardosi, Attila, Toth, Denes, Vekony, Zsofia, Vicena, Viktoria, Karadi, Oszkar, Kelemen, Dezso   +8 more
openaire   +3 more sources

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Targeting apoptosis signaling in pancreatic cancer

, 2011
The ability to escape apoptosis or programmed cell death is a hallmark of human cancers, for example pancreatic cancer. This can promote tumorigenesis, since too little cell death by apoptosis disturbs tissue homeostasis.
Simone Fulda, Fulda, Simone
core   +1 more source

Fine needle aspiration of pancreatic lesions focusing on secondary tumors with emphasis of metastatic breast cancer: A clinicopathological study with follow‐up

Cancer Medicine, 2023
Background The data on metastatic tumors to the pancreas diagnosed by fine needle aspiration (FNA) biopsy is limited. We report our experience of FNA of primary and secondary pancreatic tumors emphasizing metastatic breast cancer in the pancreas.
Maria Yanqing Chen, Neda Zarrin‐Khameh, Ya Xu   +2 more
doaj   +1 more source

TRP Channels Interactome in Pancreatic Ductal Adenocarcinoma: A Potential Therapeutic Target

Medical Sciences Forum, 2023
Integral membrane proteins, known as Transient Receptor Potential (TRP), channels are cellular sensors for various physical and chemical stimuli in the nervous system, respiratory airways, colon, pancreas, bladder, skin, cardiovascular system, and eyes ...
Ahmad Taha Khalaf, Yuanyuan Wei, Samiah Yasmin Abdul Kadir, Jamaludin Zainol, Zahraa Oglah   +4 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Wnt-11 expression promotes invasiveness and correlates with survival in human pancreatic ductal adeno carcinoma [PDF]

, 2019
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest forms of cancer, proving difficult to manage clinically. Wnt-11, a developmentally regulated gene producing a secreted protein, has been associated with various carcinomas but has not ...
Jiang, W.G., Hao, C., Owen, Sioned, Wen G. Jiang, Arisan, D.E., Sioned Owen, Pinar Uysal-Onganer, Dart, D.A., Arisan, Damla E, Hao, Chunyi, Chunyi Hao, Dart, Dafydd A, Uysal-Onganer, P., Dafydd A. Dart, Damla E Arisan, Jiang, Wen G, Uysal-Onganer, Pinar, Owen, S.   +17 more
core   +1 more source

Diffusion-weighted MR imaging of pancreatic cancer: A comparison of mono-exponential, bi-exponential and non-Gaussian kurtosis models

European Journal of Radiology Open, 2016
Objectives: To compare two Gaussian diffusion-weighted MRI (DWI) models including mono-exponential and bi-exponential, with the non-Gaussian kurtosis model in patients with pancreatic ductal adenocarcinoma.
Nikolaos Kartalis, Georgios C. Manikis, Louiza Loizou, Nils Albiin, Frank G. Zöllner, Marco Del Chiaro, Kostas Marias, Nikolaos Papanikolaou   +7 more
doaj   +1 more source