Results 111 to 120 of about 213,511 (352)

An indolent pancreatic ductal adenocarcinoma with psammoma bodies and a coincidental neuroendocrine tumor

Human Pathology: Case Reports, 2019
Pancreatic ductal adenocarcinoma is a very aggressive neoplasm with a low survival rate, comprising the majority of pancreatic malignancies. Psammoma bodies have rarely been reported in pancreatic ductal adenocarcinoma, and their clinicopathologic ...
Hongxing Gui, Christopher P. Julien, Suehyb G. Alkhatib, Michael A. Husson   +3 more
doaj  

Mixed pancreatic acinar cell-ductal adenocarcinoma: Complexities in diagnosis and treatment

Current Problems in Cancer: Case Reports, 2022
Background: Acinar cell carcinoma of the pancreas (ACC) is a rare malignancy, accounting for approximately 1-2% of all pancreatic cancers. Up to a quarter of ACCs are estimated to contain a significant component of another histology such as ...
Abdullah Nasser, Catherine L. Forse, Cynthia Walsh, Terence Moyana, Rakesh Goel   +4 more
doaj  

Adenosquamous carcinoma coexisting with intraductal papillary mucinous neoplasm of the pancreas: a case report

Journal of Medical Case Reports, 2023
Background Adenosquamous carcinoma of the pancreas is a rare variant, with a worse prognosis than pancreatic ductal adenocarcinoma; moreover, it has characteristic clinical and histopathological features.
Hirozumi Sawai, Yuka Kiriyama, Hiromasa Kuzuya, Yoshiaki Fujii, Shuhei Ueno, Shuji Koide, Masaaki Kurimoto, Kenji Yamao, Yoichi Matsuo, Mamoru Morimoto, Hajime Koide, Atsushi Kamiya   +11 more
doaj   +1 more source

Multi-Level Batch Normalization In Deep Networks For Invasive Ductal Carcinoma Cell Discrimination In Histopathology Images [PDF]

, 2019
Breast cancer is the most diagnosed cancer and the most predominant cause of death in women worldwide. Imaging techniques such as the breast cancer pathology helps in the diagnosis and monitoring of the disease. However identification of malignant cells can be challenging given the high heterogeneity in tissue absorbotion from staining agents.
arxiv   +1 more source

Targeting Replication Fork Processing Synergizes with PARP Inhibition to Potentiate Lethality in Homologous Recombination Proficient Ovarian Cancers

Advanced Science, EarlyView.
This study demonstrates that the resveratrol analogue, trans‐4,4′‐dihydroxystilbene (DHS), exhibits synergistic anti‐tumor activity with the PARP inhibitor talazoparib, inducing significant ovarian cancer cell death. The synergistic effect of this combination arises from the concurrent downregulation of homologous recombination factors and the ...
Ganesh Pai Bellare, Kshama Kundu, Papiya Dey, Krupa Thankam Philip, Nitish Chauhan, Muskan Sharma, Sankarsingh Kesharsingh Rajput, Birija Sankar Patro   +7 more
wiley   +1 more source

Lipocalin2 promotes invasion, tumorigenicity and gemcitabine resistance in pancreatic ductal adenocarcinoma. [PDF]

PLoS ONE, 2012
Lipocalin 2 (LCN2) is a small secreted protein and its elevated expression has been observed in pancreatic as well as other cancer types. LCN2 has been reported to promote resistance to drug-induced apoptosis, enhance invasion through its physical ...
Lisa Leung, Nikolina Radulovich, Chang-Qi Zhu, Shawna Organ, Bizhan Bandarchi, Melania Pintilie, Christine To, Devang Panchal, Ming Sound Tsao   +8 more
doaj   +1 more source

HNF3α Targets Nckap1l and Promotes Renal Fibrosis Following Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Hepatocyte Nuclear Factor 3 alpha (HNF3α) is significantly upregulated in renal tubular epithelial cells of CKD patients and fibrotic mice. Deletion of HNF3α mitigates IRI‐induced renal fibrosis, while overexpression worsens it. HNF3α directly regulates NCK‐associated protein 1‐like (Nckap1l), whose overexpression exacerbates fibrosis.
Ling Hou, Yan Guo, Shuang Xu, Mi Bai, Weidong Cao, Yue Zhang, Zhanjun Jia, Aihua Zhang   +7 more
wiley   +1 more source

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

Hepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu, Bingqing Xu, Xiaodong Wang, Wen‐Hua Wan, Jinying Lu, Deyuan Kong, Yu Jin, Wenhua You, Hua Sun, Xiaoxin Mu, Dongju Feng, Yun Chen   +11 more
wiley   +1 more source

Pan-p63 but not ΔNp63 (p40) expression in undifferentiated carcinoma of the pancreas

Polish Journal of Pathology, 2020
Undifferentiated carcinoma of the pancreas (UC) is a carcinoma without a definitive direction of differentiation. Tumour protein p63 is a regulator of squamous phenotype, which may also be engaged in tumour development.
Łukasz Liszka
doaj   +1 more source

A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma. [PDF]

, 2014
© 2014 Haider et al.; licensee BioMed Central. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and ...
A Jemal, A Stathis, Ai Nagano, Aldo Scarpa, Ami Desai, AV Biankin, C Curtis, C Winter, Cancer Genome Atlas Research Network, CGA Network, Claude Chelala, CQ Zhu, D Cox, EA Collisson, F Maione, FM Buffa, G Zhang, H Huang, H Janouskova, H Pei, Hemant M Kocher, HH Wong, I Kovacevic, J Adachi, JA Tercero, JD Mosley, JK Stratford, John F Marshall, Jude Fitzgibbon, Jun Wang, K Yoshihara, L Badea, Laurent Dumartin, M Hidalgo, M Taniwaki, MA Tempero, MF Brennan, MM Al-Hawary, MW Muller, N Wasif, NF Li, Nicholas R Lemoine, NL Anderson, PA Perez-Mancera, PC Boutros, PG Febbo, PJ Campbell, Prabhu Arumugam, R Grutzmann, R Grutzmann, RR Plentz, S Jones, SJ Coleman, SV Srinivasan, Syed Haider, T Barrett, Tatjana Crnogorac-Jurcevic, Thorsten Hagemann, TR Donahue, VH Coupland   +59 more
core   +4 more sources