Results 131 to 140 of about 63,783 (265)

Undifferentiated Carcinoma With Osteoclast-like Giant Cells of the Pancreas Diagnosed by EUS-Guided Fine-Needle Biopsy. [PDF]

ACG Case Rep J
Chiappetta MF, Murgiano M, de Andreis FB, Ciuffini C, Papparella LG, Vadalà di Prampero SF, Fiorani M, Costamagna G, Bulajic M.   +8 more
europepmc   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Coexisting autoimmune pancreatitis and pancreatic adenocarcinoma: Diagnostic challenges and case insights. [PDF]

Radiol Case Rep
Qajia H, Jabbari C, Choumad S, Lejouad M, Eddahoumi Y, Nassar I, Imrani K.   +6 more
europepmc   +1 more source

Durable response to selpercatinib in HOOK3-RET fusion positive, α-fetoprotein producing metastatic pancreatic ductal adenocarcinoma with intestinal-type differentiation. [PDF]

Oncol Lett
Sandhu HS, Natarajan A, Joshi S.
europepmc   +1 more source

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source

When Fat Goes Astray: Your Liver and Pancreas Get Into Trouble

Portal Hypertension &Cirrhosis, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) and intrapancreatic fat deposition (IPFD) are both common manifestations of ectopic fat accumulation. Although they share multiple risk factors, they also show notable differences in pathological features, standardization of diagnosis, and research maturity.
Yuying Chen, Li Ding, Shan Zhao, Weihong Wang, Jing Zhong, Qiang Yan   +5 more
wiley   +1 more source

Rapid Development of Diffuse-Type Remnant Pancreatic Cancer Following Obstructive Pancreatitis after Pancreaticoduodenectomy for Distal Bile Duct Carcinoma: A Case Report. [PDF]

Surg Case Rep
Tomioka A, Kawaguchi N, Kurisu Y, Ueda Y, Kushiyama S, Hamamoto H, Tanaka R, Imai Y, Komeda K, Asakuma M, Tomiyama H, Lee SW.   +11 more
europepmc   +1 more source

RNA‐binding protein RBMS1: A new target for cancer diagnosis and treatment

Precision Medical Sciences, EarlyView.
This schematic illustrates the diverse regulatory roles of RNA‐binding motif single‐stranded interacting protein 1 (RBMS1) across multiple human cancers. In breast cancer, RBMS1 stabilizes B4GALT1 mRNA to promote PD‐L1 glycosylation, modulating tumor immune escape and immunotherapy efficacy.
Xingda Run, Shiwei Jiang, Kun Xu, Yu Fan, Yanwen Chen, Ziao Liu, Zengli Miao, Wei Tian   +7 more
wiley   +1 more source

Metachronous Primary Pancreatic Neuroendocrine Tumor and Adenocarcinoma: A Case Report. [PDF]

Cancer Rep (Hoboken)
Fatyanova AS, Kalinina ME, Islamova DF, Shchekoturov IO, Lerner JV, Stashevskaya NA, Burko P, Miltiadis I.   +7 more
europepmc   +1 more source

Effects of proton therapy on the tumor immune system and clinical implications: A review

Precision Radiation Oncology, EarlyView.
Proton therapy is a novel radiotherapy technique. We review four aspects of proton therapy: application in various tumors, effects on the tumor immune system, combination with other therapies, and future challenges. By presenting these aspects in this review, we aim to inspire clinical interventions.
Rundong Liu, Mei Tao, Min Fu, Yingjia Hu, Zhen Tao, Guangyuan Hu   +5 more
wiley   +1 more source