Results 121 to 130 of about 89,882 (308)
Essential Updates 2023/2024: Minimally Invasive Surgery for Biliary Tract Cancer
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Minimally invasive surgery (MIS) for biliary tract cancer (BTC) has gained traction with advancements in laparoscopic and robotic techniques. However, its oncological impact remains uncertain. This review highlights key studies from 2023 and 2024 on MIS for BTC, including distal bile duct, hilar bile duct, gallbladder, and intrahepatic bile ...
Osamu Itano, Takuya Minagawa
wiley +1 more source
ATRA mechanically reprograms pancreatic stellate cells to suppress matrix remodelling and inhibit cancer cell invasion [PDF]
, 2016 Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy with a dismal survival rate. Persistent activation of pancreatic stellate cells (PSCs) can perturb the biomechanical homoeostasis of the tumour microenvironment to favour cancer ...
Attwood, S +10 more
core +1 more source
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Although living‐donor liver transplantation (LDLT) has become the standard treatment for end‐stage liver disease, one of its major challenges is small‐for‐size syndrome (SFSS). SFSS is characterized by severe icterus and intractable ascites, although the severity of the condition can vary.
Toru Ikegami +6 more
wiley +1 more source
Universality of a mesenchymal transition signature in invasive solid cancers [PDF]
, 2012 In this brief communication, additional computational validation is provided consistent with the unifying hypothesis that a shared biological mechanism of mesenchymal transition, reflected by a precise gene expression signature, may be present in all ...
Dimitris Anastassiou
core +1 more source
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Background Nivolumab‐including chemotherapy (nivo‐CTX) for stage IV gastric cancer (GC) may increase the chance of conversion surgery but risk of immune‐related adverse events (irAEs) during perioperative period remains unclear. Methods We examined irAEs in 36 patients with marginally resectable GC who received nivo‐CTX followed by surgery ...
Masashi Nishino +11 more
wiley +1 more source
Annals of Gastroenterological Surgery, EarlyView.This prospective randomized trial evaluated whether prehabilitation, exercise and nutrition intervention, enhance skeletal muscle mass during neoadjuvant chemotherapy in older patients with esophageal cancer undergoing esophagectomy. We also investigated whether exercise alone was sufficient to increase skeletal muscle mass, and whether nutritional ...
Keijiro Sugimura +7 more
wiley +1 more source
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Background The annual number of pancreatoduodenectomies (PDs) in the United States has increased over the past decade, but the facility types driving this growth and whether outcomes have improved remain unclear. We aimed to identify characteristics of facilities with increasing PD volumes and assess national trends in centralization ...
Koichi Tomita, Naruhiko Ikoma
wiley +1 more source
Genome-wide CRISPR screen reveals PSMA6 to be an essential gene in pancreatic cancer cells
BMC Cancer, 2019 Background Despite its relatively low incidence, pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer deaths because of the aggressive growth/metastasis of the tumor, the lack of early symptoms, and the poor treatment options.
Jesse Bakke +9 more
doaj +1 more source
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Background/Objectives Postoperative complications following pancreaticoduodenectomy (PD) remain high, particularly in patients with soft pancreatic texture. Abdominal aortic calcification volume (AACV), a surrogate marker of systemic arteriosclerosis, has been associated with increased surgical risk in lower gastrointestinal procedures ...
Masaki Horiuchi +9 more
wiley +1 more source
Annals of Gastroenterological Surgery, EarlyView.Central pancreatectomy (CP) better preserves postoperative pancreatic endocrine function than distal pancreatectomy for benign or low‐grade malignant tumors. The 75‐g oral glucose tolerance test demonstrated that CP maintained insulin secretion and glucose tolerance, highlighting its clinical advantage as a function‐preserving procedure.
Dongha Lee +9 more
wiley +1 more source