Results 191 to 200 of about 213,511 (352)

Immunosuppressive JAG2+ tumor‐associated neutrophils hamper PD‐1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells

Cancer Communications, EarlyView.
Abstract Background Tumor‐associated neutrophils (TANs) play a critical role in modulating immune responses and exhibit significant heterogeneity. Our previous study demonstrated that jagged canonical Notch ligand 2 (JAG2)+ TANs were associated with an immunosuppressive microenvironment in high‐grade serous ovarian cancer (HGSOC), but the underlying ...
Chenyang Wang, Moran Yang, Yujing Zhong, Kankan Cao, Xueling Wang, Chen Zhang, Yiying Wang, Mengdi He, Jiaqi Lu, Guodong Zhang, Yan Huang, Haiou Liu   +11 more
wiley   +1 more source

Pancreatic undifferentiated carcinoma with osteoclast‐like giant cells is genetically similar to, but clinically distinct from, conventional ductal adenocarcinoma

Journal of Pathology, 2017
C. Luchini, A. Pea, Gemma Lionheart, A. Mafficini, A. Nottegar, N. Veronese, Peter Chianchiano, L. Brosens, M. Noë, G. J. Offerhaus, R. Yonescu, Y. Ning, G. Malleo, G. Riva, P. Piccoli, I. Cataldo, P. Capelli, G. Zamboni, A. Scarpa, Laura D Wood   +19 more
semanticscholar   +1 more source

Rare case of mixed neuroendocrine-ductal pancreatic carcinoma [PDF]

HPB, 2016
Alfaro Goldaracena, A., Padilla R, A., López Basave, H., Miranda D, G.   +3 more
openaire   +2 more sources

Combating cancer immunotherapy resistance: a nano‐medicine perspective

Cancer Communications, EarlyView.
Abstract Cancer immunotherapy offers renewed hope for treating this disease. However, cancer cells possess inherent mechanisms that enable them to circumvent each stage of the immune cycle, thereby evading anti‐cancer immunity and leading to resistance.
Xiangyi Kong, Xintong Xie, Juan Wu, Xiangyu Wang, Wenxiang Zhang, Shuowen Wang, Daria Valerievna Abbasova, Yi Fang, Hongnan Jiang, Jidong Gao, Jing Wang   +10 more
wiley   +1 more source

Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types. [PDF]

, 2019
Cancer cell lines are a cornerstone of cancer research but previous studies have shown that not all cell lines are equal in their ability to model primary tumors.
Aran, D, Butte, AJ, Charalel, J, Chen, B, Goldstein, T, Sirota, M, van 't Veer, LJ, Wolf, DM, Yau, C, Yu, K   +9 more
core   +1 more source

BCDNet: A Fast Residual Neural Network For Invasive Ductal Carcinoma Detection [PDF]

arXiv
It is of great significance to diagnose Invasive Ductal Carcinoma (IDC) in early stage, which is the most common subtype of breast cancer. Although the powerful models in the Computer-Aided Diagnosis (CAD) systems provide promising results, it is still difficult to integrate them into other medical devices or use them without sufficient computation ...
arxiv  

Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor

Cancer Communications, EarlyView.
Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai, Tao Fan, Chu Xiao, Ziqin Deng, Yixiao Liu, Chunxiang Li, Jie He   +6 more
wiley   +1 more source

Case of Undifferentiated Carcinoma with Osteoclast-like Giant Cells Associated with a Mucinous Cystic Neoplasm of the Pancreas: A Diagnostic Conundrum

The Korean Journal of Gastroenterology
Undifferentiated carcinoma with osteoclast-like giant cells (UC-OGC) is a rare histological subtype of pancreatic ductal adenocarcinoma according to the World Health Organization classification of digestive system tumors.
Gargi Kapatia, Akriti Jindal, Gourav Kaushal, Ankita Soni, Manjit Kaur Rana   +4 more
doaj   +1 more source

A continuous approach of modeling tumorigenesis and axons regulation for the pancreatic cancer [PDF]

arXiv
The pancreatic innervation undergoes dynamic remodeling during the development of pancreatic ductal adenocarcinoma (PDAC). Denervation experiments have shown that different types of axons can exert either pro- or anti-tumor effects, but conflicting results exist in the literature, leaving the overall influence of the nervous system on PDAC incompletely
arxiv  

Markers for internal neoplasia in the horse

Veterinary Medicine and Science, Volume 9, Issue 1, Page 132-143, January 2023., 2023
The measurement of tumour markers in horses should be performed only in risk groups or in patients with suspicious clinical/laboratory findings (paraneoplastic syndromes). The results should be interpreted with caution as many factors (e.g., young age, pregnancy and inflammation) affect their concentration or activity.
Karolina Drozdzewska, Heidrun Gehlen
wiley   +1 more source