Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney +10 more
wiley +1 more source
Recurrent pancreatic acinar cell carcinoma following a 7-year disease-free interval: A case report and literature review. [PDF]
Mehdaoui C +5 more
europepmc +1 more source
CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén +11 more
wiley +1 more source
Proteomic and immunocytochemical analyses of squamous components in two- and three-dimensional-cultured pancreatic ductal adenocarcinoma cell lines. [PDF]
Shichi Y +10 more
europepmc +1 more source
ABSTRACT Aim To evaluate the frequency, imaging characteristics, associated factors, and clinical significance of biliary abnormalities on imaging in patients receiving lenvatinib (LEN) plus cisplatin hepatic arterial infusion chemotherapy (HAIC) for hepatocellular carcinoma (HCC).
Hirohito Osanai +10 more
wiley +1 more source
Mesopancreas excision in pancreatic ductal adenocarcinoma: recurrence patterns - a single-arm descriptive study. [PDF]
Saleh SK +7 more
europepmc +1 more source
ABSTRACT Background Associations between microbial dysbiosis and malignancies of the pancreatobiliary system have been described in recent studies. As a result of the limited number of studies that have been done specifically on the malignancies of the biliary tract, information regarding oral, biliary and tumour‐related microbial alterations was ...
Esperouz Fariba +5 more
wiley +1 more source
Clinical and prognostic implications of KRT19 expression in pancreatic ductal adenocarcinoma. [PDF]
An HJ, Cho KB, Shin KI.
europepmc +1 more source
Saliva Liquid Biopsy for Detection of Oral and Systemic Diseases
This Review summarizes and discusses the biological foundations and major classes of salivary biomarkers, outlines collection methods and analytical protocols for saliva‐based liquid biopsy, and technological convergences driven by multi‐omics approaches, artificial intelligence, and point‐of‐care devices in the application of oral and systemic ...
Irene Choi +10 more
wiley +1 more source
The Role of the Mesopancreas in Periampullary Malignancies. [PDF]
David SO +9 more
europepmc +1 more source

