Results 161 to 170 of about 1,238,265 (360)

Basal cell carcinoma and squamous cell carcinoma of the conjunctiva in a single lesion

American Journal of Ophthalmology Case Reports
Introduction: Basal cell carcinoma (BCC) occurrences in the conjunctiva are exceptionally rare. These lesions become exceedingly rarer next to an adjacent area of squamous cell carcinoma.
Melissa A. Trudrung, Cole Bacig, Brandon Vander Zee, Heather Potter   +3 more
doaj   +1 more source

RBM12 Maintains Glioma Stem Cells by Activating Amino Acid‐Dependent mTORC1 Signaling via SLC7A5 mRNA Stabilization

Advanced Science, EarlyView.
This study shows that in glioma stem cells (GSCs), RBM12 recruits ALKBH5 to remove m6A from SLC7A5 transcripts, thereby enhancing mRNA stability, which elevates large neutral amino acid (LNAA) levels and activates mTORC1, promoting GSC proliferation, self‐renewal, and tumor growth.
Hong Lei, Wenlong Luo, Shu Zhou, Lihao Wan, Peng Ling, Zhihua Huang, Zhihua Qian, Chenfei Lu, Mengyue Guo, Zhen Xue, Jun Qin, Ningwei Zhao, Jianghong Man, Wenchao Zhou, Zhiqiang Dong, Shutong Xu, Zhipeng Zhou, Xiuxing Wang, Weiwei Tao   +18 more
wiley   +1 more source

Digital necrosis with squamous cell carcinoma of the tonsil [PDF]

, 2016
Vinod Warrier,1 Ali Ahmad,1 Yaqoub Alshatti,1 Ali Jafar,2 1Department of Internal Medicine, Mubarak Al-Kabeer Hospital, Jabriya, Kuwait; 2Department of Surgical and Interventional Sciences, University College London, Royal Free Hospital, London, UK ...
Ahmad A, Alshatti Y, Warrier V, Jafar A
core  

Response Rate of Cisplatin Plus Docetaxel as Primary Treatment in Locally Advanced Head and Neck Carcinoma (Squamous Cell Types). [PDF]

Asian Pac J Cancer Prev, 2020
Nouman M, Haider G, Bukhari N, Yousuf A, Nouman R, Shaikh MR, Hussain S, Pavan B, Rahool R, Memon P, Zahoor S, Mehar K, Sami A.   +12 more
europepmc   +1 more source

A Metal‐Phenolic Nanocluster Orchestrates Mito‐Ca2+ Metabolic Autonomy for Tumor Ca2+ Interference Therapy

Advanced Science, EarlyView.
Tumor Ca2+ interference therapy suffers from self‐protective Ca2+ metabolic autoregulation. In this scenario, a versatile metal‐phenolic nanocluster (TCMH) is engineered to modulate mitochondrial calcium uniporter (MCU) ‐mediated mito‐Ca2+ metabolic autonomy.
Ronglong Chen, Jia Huang, Yuepeng Wang, Shucong Yao, Fei Wu, Juan Liu, Chunxue Song, Li Lin, Xijun Lin, Yingjie Deng, Chao Zhang, Zhiquan Huang, Zixian Huang, Lisi Xie   +13 more
wiley   +1 more source

Prognostic significance of tumor microenvironment assessed by machine learning algorithm in surgically resected non‐small cell lung cancer

Cancer Reports, EarlyView., 2023
Abstract Background A methodology to assess the immune microenvironment (IME) of non‐small cell lung cancer (NSCLC) has not been established, and the prognostic impact of IME factors is not yet clear. Aims This study aimed to assess the IME factors and evaluate their prognostic values. Methods and Results We assessed CD8+ tumor‐infiltrating lymphocyte (
Yukihiro Terada, Mitsuhiro Isaka, Akira Ono, Takuya Kawata, Masakuni Serizawa, Keita Mori, Koji Muramatsu, Kiyoshi Tone, Hirotsugu Kenmotsu, Keiichi Ohshima, Kenichi Urakami, Takeshi Nagashima, Masatoshi Kusuhara, Yasuto Akiyama, Takashi Sugino, Toshiaki Takahashi, Yasuhisa Ohde   +16 more
wiley   +1 more source

Hubungan Jumlah Sel Mast Dengan Tampilan Ekspresi Vascular Endothelial Growth Factor (VEGF) pada Cutaneous Squamous Cell Carcinoma [PDF]

, 2017
Latar Belakang: Kanker kulit non melanositik tersering adalah basalioma diikuti squamous cell carcinoma. Squamous cell carcinoma merupakan keganasan epitel skuamus. Sel mast merangsang neovaskularisasi dan angiogenesis pada beberapa tumor.
Sembiring, Edi Kerina
core  

PDGFRα+/Integrin α2+ Fibroblasts Orchestrate Tumor Budding in Oral Squamous Cell Carcinoma via Mechano‐Metabolic Symbiosis: E‐Cadherin/Integrin α2β1 Adhesion and Mitochondrial Transfer

Advanced Science, EarlyView.
PDGFA/PDGFRα signaling recruits CAFs to OSCC nests, and CAF‐OSCC contact drives tumor budding invasion. Mechanistically, heterotypic adhesion via E‐cadherin/integrin α2β1 activates YAP signaling in OSCC cells, inducing EMT. Concurrently, CAFs transfer mitochondria through TNTs, supplying ATP to fuel invasion.
Yufang Liu, Jiao Li, Juan Liu, Qi Dong, Haoyang Zhang, Yanjin Wang, Huibing Li, Ye Guan, Lei Cao, Manqing Zhang, Fangning Guo, Xue Liu, Zhen Yang, Mengmeng Lu, Hui Liu, Laiping Zhong, Tong Ji, Tingjiao Liu   +17 more
wiley   +1 more source

Squamous Cell Carcinoma and Merkel Cell Carcinoma: Diagnostic and Therapeutic Management – Expert Opinion of the Polish Dermatological Society [PDF]

The guidelines outline the clinical, pathological, and dermoscopic features of cutaneous squamous cell carcinoma and Merkel cell carcinoma, along with the recommended diagnostic and therapeutic procedures.
Martyna Sławińska, Adam Reich, Wojciech Zegarski, Maciej Pastuszczak, Michał Sobjanek, Magdalena Ciążyńska, Joanna Czuwara, Agnieszka Owczarczyk-Saczonek, Piotr Rutkowski, Aleksandra Lesiak, Agnieszka Żebrowska, Witold Owczarek, Dorota Kiprian, Joanna Narbutt, Lidia Rudnicka, Grażyna Kamińska-Winciorek, Joanna Maj, Barbara Zegarska, Jacek Szepietowski, Aleksandra Dańczak-Pazdrowska, Małgorzata Sokołowska-Wojdyło, Irena Walecka   +21 more
core   +1 more source

Underrepresentation of Black Individuals in Basal Cell and Squamous Cell Carcinoma Clinical Trials: A Comparison to an Insurance Claimant Cohort

JEADV Clinical Practice
Background Black patients often present with advanced skin cancer with worse outcomes compared to White patients. Underrepresentation of Black individuals in US basal cell carcinoma and cutaneous squamous cell carcinoma clinical trials may exacerbate ...
Mara Hartoyo, Natalie Goulett, Olivia Burke, Alyx Rosen Aigen   +3 more
doaj   +1 more source