Results 51 to 60 of about 949,312 (305)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

A Transitional Cell Tumor of the Bladder in a Young Adult: A Case Report and Review of the Literature

Journal of Urological Surgery, 2017
Bladder tumors are rarely seen in young people under the age of 40. Its development after the exposure to industrial carcinogens for many years suggests that the environmental factors play a significant role in the development of transitional cell ...
Hüseyin Koçan, Şiir Yıldırım, Enver Özdemir, Mehmet Yazıcı, Erhan Erdoğan, Fuat Ernis Su, Mehmet Uhri   +6 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Successful renal transplantation after two separate urinary tract malignancies

Indian Journal of Urology, 2008
A patient who was treated for renal cell carcinoma and transitional cell carcinoma, later presented with end stage renal disease. He was managed with hemodialysis and later underwent successful renal transplantation.
Rohit Joshi, Kim Mammen, Basant Pawar
doaj   +1 more source

Familial aggregation of bladder cancer [PDF]

Vojnosanitetski Pregled, 2011
Background. Except for smoking and certain occupational exposures, the etiology of bladder cancer is largely unknown. Several case reports have described familial aggregation of transitional cell carcinoma of the bladder.
Ilić Milena, Stojadinović Miroslav, Milosavljević Zoran   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Nonkeratinizing Carcinoma of the Sinonasal Tract: A Diagnosis of Confusing Nomenclature

Philippine Journal of Otolaryngology Head and Neck Surgery, 2011
Objective: To describe a rare case of nonkeratinizing carcinoma of the sinonasal tract and review the literature on the nomenclature of its many synonyms.
Nur Hashima Abdul Rashid, Suria Hayati Md Pauzi, Geok Chin Tan, Salina Husain, Mohd Razif Mohammad Yunus, Balwant Singh Gendeh   +5 more
doaj   +1 more source

A canine case of bladder urothelial carcinoma (transitional cell carcinoma) treated with a chemotherapeutic agent, a molecular targeted drug, and cyclooxygenase inhibitors

Journal of Japan Veterinary Cancer Society, 2023
K. Kodama, K. Kodama
semanticscholar   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

An Immunohistochemical Study in Urothelial Carcinoma of HER2/neu in Iraqi Patients

Medical Journal of Babylon
Background: Bladder carcinoma is a common urological cancer. The most common type of bladder carcinoma in the United States is urothelial carcinoma (TCC).HER-2\neu proteins seems to include in pathogenesis of urothelial carcinoma. Its over expression has
Athraa Falah Alshimerry
doaj   +1 more source