Results 251 to 260 of about 5,058,773 (393)
Gold Nanoclusters as Dual Agents for Engineering Tumor Vascular Leakiness and Performing Photothermal Therapy
Advanced Functional Materials, EarlyView.Many cancer nanotherapeutics, while potent, suffer from the inability to escape from the tumor vasculature, especially in the absence of endothelial permeability. In this work, ultrasmall gold nanoclusters could engineer nanomaterials induced endothelial leakiness (NanoEL) and harness strong NIR induced photothermal characteristics to suppress tumor ...Nengyi Ni, Kuoran Xing, Bihan Zhang, Baoteng Wang, Yinglu Chen, Jianping Xie, Xiao Sun, Jinping Wang, David Tai Leong +8 morewiley +1 more sourceMagPiezo: A Magnetogenetic Platform for Remote Activation of Endogenous Piezo1 Channels in Endothelial Cells
Advanced Functional Materials, EarlyView.MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro. Susel Del Sol‐Fernández, Mariarosaria De Simone, Yilian Fernández‐Afonso, Daniel Garcia‐Gonzalez, Pablo Martínez‐Vicente, Thomas van Zanten, Raluca M. Fratila, Maria Moros +7 morewiley +1 more sourceLaser Engineering of HfN‐Based Nanoparticles for Safe NIR‐I Photothermal and X‐ray Enhancing Cancer Therapies
Advanced Functional Materials, EarlyView.In this study, we produced HfN‐based nanoparticles via femtosecond laser ablation in acetone. The nanoparticles exhibit a red‐shifted plasmonic resonance in the NIR‐I window, colloidal stability after coating with polyethyleneglycol, and excellent biocompatibility. The photothermal and X‐ray sensitization therapeutic effects were demonstrated for tumor Julia S. Babkova, Ivan V. Zelepukin, Lyubov V. Gorelik, Anton L. Popov, Andrei I. Pastukhov, Gleb V. Tikhonowski, Maxim S. Savinov, Danil D. Kolmanovich, Nikita A. Pivovarov, Alina Yu. Kapitannikova, Anton A. Popov, Anna S. Sogomonyan, Vsevolod A. Skribitsky, Aziz B. Mirkasymov, Andrei V. Kabashin, Sergey M. Deyev +15 morewiley +1 more sourceRadiotherapy Response Patterns in Thoracic NUT Carcinoma: A Case Report. [PDF]
Respirol Case RepKashizaki F, Tsuchiya N, Watanabe S, Lin H, Orii R, Yumoto K, Yasuura Y, Kawano N, Osawa H, Koizumi H, Takahashi K. +10 moreeuropepmc +1 more sourceA Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening
Advanced Healthcare Materials, EarlyView.Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).Yuki Nakao, Makiko Mori, Yuta Sekiguchi, Iori Morita, Ryota Shindoh, Shintaro Mandai, Tamami Fujiki, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Ayumi Suzuki, Yuji Nashimoto, Hirokazu Kaji, Yuma Waseda, Soichiro Yoshida, Yasuhisa Fujii, Eisei Sohara, Shinichi Uchida, Kensuke Miyake, Yutaro Mori +20 morewiley +1 more sourceComprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma
Cell, 2017 Adrian Ally, Miruna Balasundaram, R. Carlsen, E. Chuah, A. Clarke, Noreen Dhalla, R. Holt, Steven J. M. Jones, Darlene Lee, Yussanne Ma, M. Marra, Michael Mayo, Richard A. Moore, A. Mungall, J. Schein, Payal Sipahimalani, Angela Tam, N. Thiessen, Dorothy Cheung, Tina Wong, Denise Brooks, A. G. Robertson, R. Bowlby, K. Mungall, S. Sadeghi, Liu Xi, K. Covington, E. Shinbrot, D. Wheeler, R. Gibbs, L. Donehower, Linghua Wang, Jay Bowen, J. Gastier-Foster, M. Gerken, Carmen Helsel, K. Leraas, T. Lichtenberg, N. Ramirez, L. Wise, E. Zmuda, S. Gabriel, M. Meyerson, C. Cibulskis, Bradley A. Murray, J. Shih, R. Beroukhim, A. Cherniack, S. Schumacher, G. Saksena, C. Pedamallu, L. Chin, G. Getz, M. Noble, Hailei Zhang, David I Heiman, Juok Cho, Nils Gehlenborg, Douglas Voet, Pei Lin, S. Frazer, T. DeFreitas, S. Meier, M. Lawrence, Jaegil Kim, C. Creighton, D. Muzny, H. Doddapaneni, Jianhong Hu, Min Wang, Donna Morton, V. Korchina, Yi Han, H. Dinh, L. Lewis, Michelle Bellair, Xiuping Liu, J. Santibanez, R. Glenn, Sandy Lee, Walker Hale, J. Parker, M. Wilkerson, D. Hayes, Sheila M. Reynolds, I. Shmulevich, Wei Zhang, Yuexin Liu, L. Iype, H. Makhlouf, M. Torbenson, S. Kakar, M. Yeh, D. Jain, D. Kleiner, R. Dhanasekaran, H. El‐Serag, S. Yim, J. Weinstein, L. Mishra, Jianping Zhang, Rehan Akbani, Shiyun Ling, Z. Ju, X. Su, A. Hegde, G. Mills, Yiling Lu, J. Chen, Ju-Seog Lee, B. Sohn, Jae-Jun Shim, P. Tong, H. Aburatani, Shogo Yamamoto, K. Tatsuno, Wei Li, Zheng Xia, Nicolas Stransky, E. Seiser, F. Innocenti, Jianjiong Gao, Ritika Kundra, Hongxin Zhang, Zachary J. Heins, Angelica Ochoa, C. Sander, M. Ladanyi, R. Shen, Arshi Arora, F. Sánchez-Vega, N. Schultz, K. Kasaian, Amie Radenbaugh, K. Bissig, D. Moore, Y. Totoki, Hiromi Nakamura, T. Shibata, C. Yau, Kiley S. Graim, Josh M Stuart, D. Haussler, B. Slagle, A. Ojesina, Panagiotis Katsonis, Amanda M Koire, O. Lichtarge, Teng-Kuei Hsu, M. Ferguson, John A. Demchok, Ina Felau, Margi Sheth, R. Tarnuzzer, Zhining Wang, Liming Yang, J. Zenklusen, J. Zhang, C. Hutter, H. Sofia, R. Verhaak, Siyuan Zheng, F. Lang, Sudha Chudamani, Jia Liu, Laxmi Lolla, Ye Wu, R. Naresh, T. Pihl, Charlie Sun, Yunhu Wan, C. Benz, Amy H. Perou, L. Thorne, L. Boice, Meijuan Huang, W. Rathmell, H. Noushmehr, F. Saggioro, D. Tirapelli, C. G. C. Júnior, Ê. D. Mente, O. C. Silva, F. Trevisan, K. Kang, K. Ahn, N. Giama, C. Moser, T. Giordano, Michelle Vinco, Theodore H. Welling, D. Crain, Erin E. Curley, J. Gardner, D. Mallery, S. Morris, J. Paulauskis, R. Penny, C. Shelton, T. Shelton, R. Kelley, Joong-Won Park, V. Chandan, L. Roberts, O. Bathe, C. Hagedorn, J. Auman, D. O'Brien, J. Kocher, Corbin D. Jones, P. Mieczkowski, C. Perou, Tara J. Skelly, Donghui Tan, Umadevi Veluvolu, S. Balu, T. Bodenheimer, A. Hoyle, S. Jefferys, S. Meng, Lisle E. Mose, Yan Shi, J. Simons, Matthew G. Soloway, J. Roach, K. Hoadley, S. Baylin, Hui Shen, T. Hinoue, Moiz Bootwalla, D. V. Berg, D. Weisenberger, Phillip H. Lai, Andrea E Holbrook, Mario Berrios, P. Laird +235 moresemanticscholar +1 more source