Results 1 to 10 of about 1,545,686 (292)

TRIM21 inhibits irradiation-induced mitochondrial DNA release and impairs antitumour immunity in nasopharyngeal carcinoma tumour models

open access: yesNature Communications, 2023
The molecular mechanisms determining the response to radiotherapy remain incompletely understood. Here, the authors demonstrate that the E3 ubiquitin ligase and intracellular Fc receptor, TRIM21, impairs CD8+ T cell responses in nasopharyngeal carcinoma ...
Jun-Yan Li   +19 more
doaj   +2 more sources

The Chinese Society of Clinical Oncology (CSCO) clinical guidelines for the diagnosis and treatment of nasopharyngeal carcinoma

open access: yesCancer Communications, 2021
Nasopharyngeal carcinoma (NPC) is a malignant epithelial tumor originating in the nasopharynx and has a high incidence in Southeast Asia and North Africa.
Xia He, Shaojun Lin, Yupei Chen
exaly   +2 more sources

Clinical advances in nasopharyngeal carcinoma surgery and a video demonstration

open access: yesVisualized Cancer Medicine, 2021
Nasopharyngeal carcinoma (NPC) is highly radiosensitive, and radiotherapy is recommended for newly diagnosed NPC. Because of the poor visual surgical field, narrow operating space, difficulty protecting the internal carotid artery (ICA) and poor wound ...
Ding Xi   +6 more
doaj   +1 more source

Nasopharyngeal Carcinoma [PDF]

open access: yesEar, Nose & Throat Journal, 2005
Incidence of nasopharyngeal carcinoma has remained high in endemic regions. Diagnosing the disease in the early stages requires a high index of clinical acumen and, although most cross-sectional imaging investigations show the tumour with precision, confirmation is dependent on histology.
Wei, WI, Sham, JST
openaire   +7 more sources

Nasopharyngeal carcinoma in situ in nasopharyngeal carcinoma. [PDF]

open access: yesJournal of Clinical Pathology, 1992
AIMS: To assess the presence of carcinoma in situ (CIS) in patients with nasopharyngeal carcinoma (NPC) and to see if the number of biopsy sites facilitates detection of CIS. METHODS: Formalin fixed, paraffin wax embedded biopsy specimens (n = 285) from 187 patients with NPC in 1987 were studied for the presence of CIS as well as for the histological ...
Chan, CW   +4 more
openaire   +3 more sources

The Evolving Epidemiology of Nasopharyngeal Carcinoma

open access: yesCancer Epidemiology, Biomarkers and Prevention, 2021
Background: The epidemiology of nasopharyngeal carcinoma (NPC) has long been a source of fascination due to the malignancy's striking geographic distribution, the involvement of the oncogenic Epstein–Barr virus (EBV), the unique association with intake ...
E. Chang, W. Ye, Yi-Xin Zeng, H. Adami
semanticscholar   +1 more source

The role of the bacterial microbiome in the treatment of cancer

open access: yesBMC Cancer, 2021
The human microbiome is defined as the microorganisms that reside in or on the human body, such as bacteria, viruses, fungi, and protozoa, and their genomes.
Zi-Kun Yu   +6 more
doaj   +1 more source

Accumulated Dose Deviation of Rotational and Residual Setup Errors on Nasopharyngeal Carcinoma Using MIM Treated by Helical Tomotherapy

open access: yesTechnology in Cancer Research & Treatment, 2023
Background To analyze the relationship between the rotational and residual setup errors and the dose deviation on nasopharyngeal carcinoma (NPC) treated by helical tomotherapy (HT).
Wenyan Yao MS   +10 more
doaj   +1 more source

The role of Epstein–Barr virus in nasopharyngeal carcinoma

open access: yesFrontiers in Microbiology, 2023
Nasopharyngeal carcinoma (NPC) is a metastasis-prone malignancy closely associated with the Epstein–Barr virus (EBV). Despite ubiquitous infection of EBV worldwide, NPC incidences displayed predominance in certain ethnic groups and endemic regions.
Zhijie Su, P. Siak, C. Leong, S. Cheah
semanticscholar   +1 more source

Nasopharyngeal carcinoma cells promote regulatory T cell development and suppressive activity via CD70-CD27 interaction

open access: yesNature Communications, 2023
Despite the intense CD8+ T-cell infiltration in the tumor microenvironment of nasopharyngeal carcinoma, anti-PD-1 immunotherapy shows an unsatisfactory response rate in clinical trials, hindered by immunosuppressive signals.
Lanqi Gong   +21 more
semanticscholar   +1 more source

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