Results 31 to 40 of about 73,649 (308)

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Humanistic nursing care and quality of life in patients with nasopharyngeal carcinoma: a prospective observational study

BMC Nursing
Purposes To study the relationship between nursing humanistic care and quality of life in patients with nasopharyngeal carcinoma (NPC). Methods A total of 382 NPC patients of Sun Yat-sen University Cancer Center were included from October 1, 2018, to ...
Cong Wang, Yanhua Xiao, Liping Wu, Yan He, Min Chen, Wen Hu, Yuying Fan   +6 more
doaj   +1 more source

Limited recurrence distance of glioblastoma under modern radiotherapy era

BMC Cancer, 2021
Background The optimal treatment volume for Glioblastoma multiforme (GBM) is still a subject of debate worldwide. The current study was aimed to determine the distances between recurring tumors and the edge of primary lesions, and thereby provide ...
Ziwei Tu, Huifen Xiong, Yang Qiu, Guoqing Li, Li Wang, Shiyi Peng   +5 more
doaj   +1 more source

Paclitaxel liposome, cisplatin and 5-fluorouracil-based induction chemotherapy followed by de-escalated intensity-modulated radiotherapy with concurrent cisplatin in stage IVA–IVB childhood nasopharyngeal carcinoma in endemic area: a phase II, single-arm trialResearch in context

The Lancet Regional Health. Western Pacific, 2023
Summary: Background: Previous studies demonstrated that induction chemotherapy (IC) followed by de-escalated chemoradiotherapy adapted to tumor response was effective in treating childhood nasopharyngeal carcinoma (NPC), but the toxicity profile of this
Dong-Hua Luo, Xiao-Yun Li, Shan-Shan Guo, Wan-Ping Guo, Li-Ting Liu, Hao-Yuan Mo, Ling Guo, Xiao-Fei Lv, Li-Zhi Liu, Ji-Bin Li, Qing Liu, Pan Wang, Xue-Song Sun, Sai-Lan Liu, Qiu-Yan Chen, Lin-Quan Tang, Hai-Qiang Mai   +16 more
doaj   +1 more source

Cancer Immunotherapy for Nasopharyngeal Carcinoma

, 2019
Endemic nasopharyngeal carcinoma (NPC) is associated with Epstein–Barr virus (EBV) type II latent infection, and tumor cells expressing such viral antigens are attractive targets for treatment.
Lee, VHF, Victor H.F. Lee, Nicholls, JM, John M. Nicholls, Dora L.W. Kwong, Kwong, DLW   +5 more
core   +1 more source

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen   +13 more
wiley   +1 more source

Outcomes of patients in nasopharyngeal adenoid cystic carcinoma in the IMRT era: a single-center experience

BMC Cancer
Objective Nasopharyngeal adenoid cystic carcinoma (NACC) is a rare malignancy with special biological features. Controversies exist regarding the treatment approach and prognostic factors in the IMRT era.
Wen-Bin Wu, Wu-Lin Cai, Ye-Hao Zou, Rui You, You-Ping Liu, Zhao-Di Yuan, Qiong Li, Wen-Chao Li, Zhi-Xuan Pi, Yu-Long Xie, Kai Wen, Ming-Yuan Chen, Rui Sun   +12 more
doaj   +1 more source

Stratification of Candidates for Induction Chemotherapy in Stage III-IV Nasopharyngeal Carcinoma: A Large Cohort Study Based on a Comprehensive Prognostic Model

Frontiers in Oncology, 2020
Objective: To establish a prognostic index (PI) for patients with stage III-IV nasopharyngeal carcinoma (NPC) patients to personalize recommendations for induction chemotherapy (IC) before intensity-modulated radiotherapy (IMRT).Patients and Methods ...
Xue-Song Sun, Xue-Song Sun, Bei-Bei Xiao, Bei-Bei Xiao, Zi-Jian Lu, Zi-Jian Lu, Sai-Lan Liu, Sai-Lan Liu, Qiu-Yan Chen, Qiu-Yan Chen, Li Yuan, Lin-Quan Tang, Lin-Quan Tang, Hai-Qiang Mai, Hai-Qiang Mai   +14 more
doaj   +1 more source

Age Standardized Rate ( ASR ) and Age Standardized Cancer Ratio ( ASCR ) of Nasopharyngeal Cancer in Kariadi Central Hospital during 2002 - 2011 [PDF]

, 2012
Background: Every year in all over the world, the incidence of nasopharyngeal carcinoma increases. In Indonesia, there was no accurate data. To get an accurate result, without using this standardization, it would be unclear if differing mortality rates ...
Puspita, M. (Merry), Prasetyo, A. (Awal), PUSPITA, MERRY, Prasetyo, Awal   +3 more
core  

Standard of Care for Nasopharyngeal Carcinoma (2018–2020)

, 2019
Nasopharyngeal carcinoma is one of the greatest challenges for oncologists. The standard of care has evolved drastically during the past 3 decades, leading to a gratifying improvement in outcomes.
Lee, VHF, Lam, KO, Lee, WMA
core   +1 more source