Results 11 to 20 of about 131,451 (349)

A global view of the oncogenic landscape in nasopharyngeal carcinoma : an integrated analysis at the genetic and expression levels [PDF]

, 2012
Previous studies have reported that the tumour cells of nasopharyngeal carcinoma (NPC) exhibit recurrent chromosome abnormalities. These genetic changes are broadly assumed to lead to changes in gene expression which are important for the pathogenesis of
Amari, Aicha, Arrand, J. R. (John R.), Bell, Andrew I., Chen, Xiaoyi, Dawson, Christopher W., Derkaoui, K. Dalia, Hu, Chunfang, Joab, Irène, Maloney, Stephanie L., Murray, Paul G., Nicholls, J. M. (John M.), Shao, Jian-Yong, Sihota, Sim K., Wei, Wenbin, Woodman, Ciaran B. J., Yao, Yunhong, Young, Lawrence S.   +16 more
core   +12 more sources

Unique case of inverted papilloma of septum with nasopharyngeal carcinoma:Is it a metachronous tumour? [PDF]

, 2020
Inverted papilloma is a rare and benign tumour. It affects the nasal cavity and paranasal sinuses, has a high rate of recurrence and is associated with malignant transformation.
Ferguson, Aaron S. J., Flach, Susanne, Manickavasagam, Jaiganesh, White, Paul S., White, Sharon   +4 more
core   +3 more sources

A regulatory mutant on TRIM26 conferring the risk of nasopharyngeal carcinoma by inducing low immune response. [PDF]

, 2018
The major histocompatibility complex (MHC) is most closely associated with nasopharyngeal carcinoma (NPC), but the complexity of its genome structure has proven challenging for the discovery of causal MHC loci or genes.
Cheng, Zhi, Dong, Lei, Han, Ming-Yu, Huang, Zhong-Xi, Jiang, Tao, Li, Jin-Bang, Li, Xin, Li, Xin, Liu, Teng-Fei, Liu, Xiao, Long, Xiao-Bing, Lyu, Xiao-Ming, Qiu, Mo-Chang, Sun, Tao, Wang, Jia-Hong, Wang, Jian-Guo, Wang, Qian, Wang, Shuang, Wei, Gan-Guan, Yang, Xue-Xi, Yao, Kaitai, Zhang, Bo, Zhang, Long-Cheng, Zhao, Manli, Zheng, Hou-Feng, Zheng, Lu, Zhu, Xiao-Wei, Zuo, Xian-Bo   +27 more
core   +2 more sources

Minimally invasive surgery alone compared with intensity-modulated radiotherapy for primary stage I nasopharyngeal carcinoma

Cancer Communications, 2019
Background The National Comprehensive Cancer Network guidelines recommend intensity-modulated radiotherapy (IMRT) as the primary curative treatment for newly diagnosed nasopharyngeal carcinoma (NPC), but the radiation-related complications and relatively
You-Ping Liu, Xing Lv, Xiong Zou, Yi-Jun Hua, Rui You, Qi Yang, Le Xia, Shao-Yan Guo, Wen Hu, Meng-Xia Zhang, Si-Yuan Chen, Mei Lin, Yu-Long Xie, Li-Zhi Liu, Rui Sun, Pei-Yu Huang, Wei Fan, Xiang Guo, Ming-Huang Hong, Ming-Yuan Chen   +19 more
doaj   +1 more source

Short‐term efficacy and long‐term survival of nasopharyngeal carcinoma patients with radiographically visible residual disease following observation or additional intervention: A real‐world study in China

Laryngoscope Investigative Otolaryngology, 2022
Background To explore the short‐ and long‐term outcomes in patients with nasopharyngeal carcinoma (NPC) with magnetic resonance imaging (MRI)‐detected residual disease at 3 months post‐treatment who received intervention either promptly (0 month) or ...
Ying‐Ying Huang, Xun Cao, Zhuo‐Chen Cai, Jia‐Yu Zhou, Xiang Guo, Xing Lv   +5 more
doaj   +1 more source

Image findings of cranial nerve pathology on [18F]-2- deoxy-D-glucose (FDG) positron emission tomography with computerized tomography (PET/CT): a pictorial essay. [PDF]

, 2015
This article aims to increase awareness about the utility of (18)F -FDG-PET/CT in the evaluation of cranial nerve (CN) pathology. We discuss the clinical implication of detecting perineural tumor spread, emphasize the primary and secondary (18)F -FDG-PET/
Muzaffar, Razi, Osman, Medhat M, Raslan, Osama A, Shetty, Vilaas   +3 more
core   +1 more source

Targeting hypoxia-inducible factor-1α (HIF-1α) in combination with antiangiogenic therapy: a phase I trial of bortezomib plus bevacizumab. [PDF]

, 2014
PurposeWe hypothesized that bortezomib, an agent that suppresses HIF-1α transcriptional activity, when combined with bevacizumab, would obviate the HIF-1α resistance pathway.
Amin, Hesham M, Angelo, Laura S, Falchook, Gerald S, Hess, Kenneth, Hong, David, Howard, Adrienne N, Huang, Mei, Jackson, Edward F, Janku, Filip, Kurzrock, Razelle, Lawhorn, Kristie N, Naing, Aung, Ng, Chaan S, Parkhurst, Kristin L, Tannir, Nizar M, Vishwamitra, Deeksha, Wheler, Jennifer J   +16 more
core   +2 more sources

Incidence, consequences, and predictors of serious chemotherapy‐induced thrombocytopenia in nasopharyngeal carcinoma

Cancer Medicine, 2023
Objectives This study aimed to investigate the incidence, consequences, and predictors of serious chemotherapy‐induced thrombocytopenia (CIT) in nasopharyngeal carcinoma (NPC).
Lu‐Lu Zhang, Xi Chen, Ying‐Ying Huang, Chi‐Xiong Liang, Meng‐Yun Qiang, Zhuo‐Chen Cai, Ze‐Jiang Zhan, Ying Deng, Jia‐Yu Zhou, Hao‐Yang Huang, Xiang Guo, Xing Lv   +11 more
doaj   +1 more source

Induction chemotherapy in the treatment of nasopharyngeal carcinoma: Clinical outcomes and patterns of care [PDF]

, 2018
The role of induction chemotherapy in nasopharyngeal carcinoma (NPC) remains controversial. The primary aim of this study was to use the National Cancer Database to evaluate the patterns of care of induction chemotherapy in NPC and its impact on overall ...
Adkins, Douglas, Barnes, Justin, Daly, Mackenzie D, Gabani, Prashant, Gay, Hiram A, Lin, Alexander J, Oppelt, Peter, Rich, Jason T, Rudra, Soumon, Thorstad, Wade L, Zevallos, Jose P   +10 more
core   +2 more sources

The CXCL5/CXCR2 axis contributes to the epithelial-mesenchymal transition of nasopharyngeal carcinoma cells by activating ERK/GSK-3β/snail signalling

Journal of Experimental & Clinical Cancer Research, 2018
Background Distant metastasis is the major cause of treatment failure in patients with nasopharyngeal carcinoma (NPC). Although several biomarkers correlate with metastasis and prognosis, the molecular mechanisms of NPC development and progression remain
Wen-Ze Qiu, Hai-Bo Zhang, Wei-Xiong Xia, Liang-Ru Ke, Jing Yang, Ya-Hui Yu, Hu Liang, Xin-Jun Huang, Guo-Ying Liu, Wang-Zhong Li, Yan-Qun Xiang, Tie-Bang Kang, Xiang Guo, Xing Lv   +13 more
doaj   +1 more source