Results 11 to 20 of about 1,545,686 (292)

Immunotherapy for nasopharyngeal carcinoma: Current status and prospects (Review)

International Journal of Oncology, 2023
Nasopharyngeal carcinoma (NPC) is an epithelial tumor located in the nasopharynx and is highly associated with Epstein-Barr virus (EBV) infection. Although radiotherapy alone can cure ~90% of patients with early-stage disease, >70% of patients with NPC ...
Huageng Huang, Yu-yi Yao, Xinyi Deng, Zongyao Huang, Yungchang Chen, Zhao Wang, H. Hong, He Huang, Tongyu Lin   +8 more
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Recurrent/Metastatic Nasopharyngeal Carcinoma Treatment from Present to Future: Where Are We and Where Are We Heading?

Current Treatment Options in Oncology, 2023
Nasopharyngeal carcinoma (NPC) is distinct in its anatomic location and biology from other epithelial head and neck cancer (HNC). There are 3 WHO subtypes, which considers the presence of Epstein-Barr virus (EBV) and other histopathology features ...
J. J. Juarez-Vignon Whaley, M. Afkhami, M. Onyshchenko, E. Massarelli, S. Sampath, A. Amini, D. Bell, V. Villaflor   +7 more
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Immunotherapeutic approaches in EBV-associated nasopharyngeal carcinoma

Frontiers in Immunology, 2023
Epstein–Barr virus (EBV) was the first tumor virus in humans. Nasopharyngeal carcinoma (NPC) accounts for approximately 60% of the 200,000 new tumor cases caused by EBV infection worldwide each year.
Wenting Li, Xiaobing Duan, Xingxing Chen, Meixiao Zhan, H. Peng, Y. Meng, Xiaobin Li, Xian-Yang Li, Guofu Pang, Xiaohui Dou   +9 more
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Chemotherapy in Combination With Radiotherapy for Definitive-Intent Treatment of Stage II-IVA Nasopharyngeal Carcinoma: CSCO and ASCO Guideline.

Journal of Clinical Oncology, 2021
PURPOSE The aim of this joint guideline is to provide evidence-based recommendations to practicing physicians and other healthcare providers on definitive-intent chemoradiotherapy for patients with stage II-IVA nasopharyngeal carcinoma (NPC).
Yupei Chen, Nofisat Ismaila, M. Chua, A. Colevas, R. Haddad, S. Huang, Joseph Wee, Alexander C. Whitley, J. Yi, S. Yom, Anthony T. C. Chan, Chaosu Hu, J. Lang, Q. Le, Anne Lee, N. Lee, Jin-Ching Lin, B. Ma, T. J. Morgan, J. Shah, Ying Sun, Jun Ma   +21 more
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Symptomatic venous thromboembolism associated with peripherally inserted central catheters predicts a worse survival in nasopharyngeal carcinoma: results of a large cohort, propensity score–matched analysis

BMC Cancer, 2018
Background Despite increasing use, symptomatic venous thromboembolism (VTE) associated with peripherally inserted central catheter (PICC) is a common complication in nonmetastatic nasopharyngeal carcinoma (NPC) patients.
Yu-Jing Liang, Lin-Quan Tang, Xue-Song Sun, Yu-Ying Fan, Jin-Jie Yan, Yu-Yun Du, Shan-Shan Guo, Li-Ting Liu, Hao-Jun Xie, Sai-Lan Liu, Qing-Nan Tang, Xiao-Yun Li, Hai-Qiang Mai, Qiu-Yan Chen   +13 more
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Depletion of SOD2 enhances nasopharyngeal carcinoma cell radiosensitivity via ferroptosis induction modulated by DHODH inhibition

BMC Cancer, 2023
Background Recurrence due to the development of radioresistance remains a major challenge in the clinical management of nasopharyngeal carcinoma. The objective of this study was to increase the sensitivity of nasopharyngeal carcinoma cells to ionizing ...
Alvan Amos, N. Jiang, D. Zong, Jiajia Gu, Jiawei Zhou, L. Yin, Xia He, Yong Xu, Li-rong Wu   +8 more
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EBV infection-induced GPX4 promotes chemoresistance and tumor progression in nasopharyngeal carcinoma

Cell Death and Differentiation, 2022
Epstein–Barr virus (EBV) was the first oncogenic virus identified in humans. It is primarily associated with multiple lymphoid and epithelial cancers, including nasopharyngeal carcinoma (NPC).
Li Yuan, Shibing Li, Qiu-Yan Chen, Tian-Liang Xia, D. Luo, Liangji Li, Sai-Lan Liu, Shan-Shan Guo, Li-Ting Liu, Chaochao Du, G. Jia, Xiaoyun Li, Zi-Jian Lu, Zhenchong Yang, Huanliang Liu, Haiqiang Mai, Linquan Tang   +16 more
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Association of Intratumoral Microbiota With Prognosis in Patients With Nasopharyngeal Carcinoma From 2 Hospitals in China

JAMA Oncology, 2022
Key Points Question Is there characteristic microbiota in nasopharyngeal carcinoma (NPC) tissues and, if so, is it associated with prognosis? Findings In this multicenter cohort study including 802 patients with NPC, we confirmed the existence of ...
Han Qiao, Xirong Tan, Hui Li, Junyan Li, Xiaozhong Chen, Yingqin Li, Wen-Fei Li, Ling-Long Tang, G. Zhou, Yuan Zhang, Yelin Liang, Qingmei He, Yin Zhao, Shengyan Huang, Sha Gong, Qian Li, Mingxia Ye, Kailin Chen, Ying Sun, Jun Ma, Na Liu   +20 more
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Alpha-fetoprotein–producing recurrent nasopharyngeal carcinoma: A case report

SAGE Open Medical Case Reports, 2021
Alpha-fetoprotein hardly increased due to nasopharyngeal cancer. In this article, we reported a 57-year-old male nasopharyngeal carcinoma patient who had posttreatment subscapular metastasis with high serum alpha-fetoprotein but negative plasma Epstein ...
Zhen-Chong Yang, Mei-Juan Luo, Li-Li Liu, Mu-Yan Cai, Yu-Jing Liang, Qiu-Yan Chen, Lin-Quan Tang, Hai-Qiang Mai   +7 more
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Tumour heterogeneity and intercellular networks of nasopharyngeal carcinoma at single cell resolution

Nature Communications, 2021
The heterogeneous nature of tumour microenvironment (TME) underlying diverse treatment responses remains unclear in nasopharyngeal carcinoma (NPC). Here, we profile 176,447 cells from 10 NPC tumour-blood pairs, using single-cell transcriptome coupled ...
Yang Liu, Shuai He, Xiliang Wang, W. Peng, Qiu-Yan Chen, Dong-Mei Chi, Jie-Rong Chen, Bo W. Han, G. Lin, Yi-Qi Li, Qian-Yu Wang, Roujun Peng, Pan-Pan Wei, Xiang Guo, Bo Li, Xiaojun Xia, H. Mai, Xue-Da Hu, Zemin Zhang, Yi-Xin Zeng, J. Bei   +20 more
semanticscholar   +1 more source