Results 21 to 30 of about 131,451 (349)

Spatial heterogeneity of immune infiltration predicts the prognosis of nasopharyngeal carcinoma patients

OncoImmunology, 2021
Spatial information on the tumor immune microenvironment is of clinical relevance. Here, we aimed to quantify the spatial heterogeneity of lymphocytes and cancer cells and evaluated its prognostic value in patients with nasopharyngeal carcinoma (NPC ...
Ya-Qin Wang, Xu Liu, Cheng Xu, Wei Jiang, Shuo-Yu Xu, Yu Zhang, Ye Lin Liang, Jun-Yan Li, Qian Li, Yu-Pei Chen, Yin Zhao, Jing-Ping Yun, Na Liu, Ying-Qin Li, Jun Ma   +14 more
doaj   +1 more source

Adding Concurrent Chemotherapy Significantly Improves the Survival of Stage II-IVb Nasopharyngeal Carcinoma Patients Treated With Concurrent Anti-EGFR Agents

Frontiers in Oncology, 2021
ObjectiveAnti-EGFR Targeted agents were found to be capable of modulating the antitumor immunity in head and neck cancer and become more and more frequently used in the treatment of nasopharyngeal carcinoma(NPC).
Zi-Kun Yu, Zi-Kun Yu, Xu-Yin Chen, Xu-Yin Chen, Si-Han Liu, Si-Han Liu, You-Ping Liu, You-Ping Liu, Rui You, Rui You, Pei-Yu Huang, Pei-Yu Huang   +11 more
doaj   +1 more source

Nasopharyngeal carcinoma in Uganda [PDF]

Cancer, 1972
Review of histologic material seen in Uganda over the 5-year period, 1964–1968, revealed 83 cases of nasopharyngeal carcinoma out of a total of 7,000 malignant tumors. All tumors conformed to the anaplastic type, but those with a small cell structure occurred in older men than those made up of larger cells. The histologic appearances of this tumor were
R, Schmauz, A C, Templeton
openaire   +2 more sources

Nasopharyngeal carcinoma [PDF]

Orphanet Journal of Rare Diseases, 2006
Nasopharyngeal carcinoma (NPC) is a tumor arising from the epithelial cells that cover the surface and line the nasopharynx. The annual incidence of NPC in the UK is 0.3 per million at age 0-14 years, and 1 to 2 per million at age 15-19 years. Incidence is higher in the Chinese and Tunisian populations.
openaire   +3 more sources

TRIM21 inhibits irradiation-induced mitochondrial DNA release and impairs antitumour immunity in nasopharyngeal carcinoma tumour models

Nature Communications, 2023
The molecular mechanisms determining the response to radiotherapy remain incompletely understood. Here, the authors demonstrate that the E3 ubiquitin ligase and intracellular Fc receptor, TRIM21, impairs CD8+ T cell responses in nasopharyngeal carcinoma ...
Jun-Yan Li, Yin Zhao, Sha Gong, Miao-Miao Wang, Xu Liu, Qing-Mei He, Ying-Qin Li, Sheng-Yan Huang, Han Qiao, Xi-Rong Tan, Ming-Liang Ye, Xun-Hua Zhu, Shi-Wei He, Qian Li, Ye-Lin Liang, Kai-Lin Chen, Sai-Wei Huang, Qing-Jie Li, Jun Ma, Na Liu   +19 more
doaj   +1 more source

Nasopharyngeal carcinoma in children [PDF]

Cancer, 1976
Ten children with lymphoepithelioma of the nasopharynx were reviewed. Six had regional spread at presentation and four developed distant metastases. Seven patients are alive, six free of disease. The 5-year survival rate was 62.5% of this series. Five patients presented later with endocrine abnormalities probably related to the radiotherapy; these ...
C H, Fernandez, A, Cangir, N A, Samaan, R, Rivera   +3 more
openaire   +2 more sources

Add-on individualizing prediction of nasopharyngeal carcinoma using deep-learning based on MRI: A multicentre, validation study

iScience, 2022
Summary: In nasopharyngeal carcinoma, deep-learning extracted signatures on MR images might be correlated with survival. In this study, we sought to develop an individualizing model using deep-learning MRI signatures and clinical data to predict survival
Xun Cao, Xi Chen, Zhuo-Chen Lin, Chi-Xiong Liang, Ying-Ying Huang, Zhuo-Chen Cai, Jian-Peng Li, Ming-Yong Gao, Hai-Qiang Mai, Chao-Feng Li, Xiang Guo, Xing Lyu   +11 more
doaj   +1 more source

Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication. [PDF]

, 2016
The transcription factor Yin Yang 1 (YY1) is frequently overexpressed in cancerous tissues compared to normal tissues and has regulatory roles in cell proliferation, cell viability, epithelial-mesenchymal transition, metastasis and drug/immune resistance.
Bonavida, Benjamin, Garbán, Hermes, Kaufhold, Samantha   +2 more
core   +2 more sources

The Prognostic Role of Plasma Epstein-Barr Virus DNA Levels in the Middle of Intensity Modulated Radiation Therapy to Guide Cisplatin Dose Recommendation in Concurrent Chemoradiation Therapy in Patients With Locally Advanced Nasopharyngeal Carcinoma: A Large Cohort Study

Advances in Radiation Oncology, 2022
Purpose: Our purpose was to investigate the prognostic role of plasma Epstein-Barr virus (EBV) DNA levels in the middle of intensity modulated radiation therapy (IMRT).
Zhen-Chong Yang, MD, Chao-Chao Du, PhD, Li-Ting Liu, MD, Yu-Jing Liang, MD, Lin-Quan Tang, MD, Qiu-Yan Chen, MD, Hai-Qiang Mai, MD, PhD, Shan-Shan Guo, MD   +7 more
doaj   +1 more source

Upregulation of Id1 by Epstein-Barr Virus-encoded LMP1 confers resistance to TGFβ-mediated growth inhibition [PDF]

, 2010
Background Epstein-Barr virus (EBV)-encoded LMP1 protein is commonly expressed in nasopharyngeal carcinoma (NPC). LMP1 is a prime candidate for driving tumourigenesis given its ability to activate multiple signalling pathways and to alter the expression
Dawson, Christopher W., Lo, Angela K. F., Lo, Kwok W., Young, Lawrence S., Yu, Yanxing   +4 more
core   +3 more sources