Results 251 to 260 of about 2,901,567 (312)

Halofuginone is a Molecular Glue Degrader of Integrin β4

Advanced Science, EarlyView.
Integrin β4 overexpression is linked to aggressive tumors and poor prognosis, but targeted therapies are lacking. We identified halofuginone (HF) as a molecular glue degrader that promotes integrin β4 degradation via the CRL4BWDR18 E3 ligase. HF suppresses tumor progression in vitro and in vivo, offering a new strategy for targeting oncogenic ...
Wei Gong, Di Yang, Junrui Tian, Yufei Chai, Tiantian Yu, Qingnan Wu, Yan Wang, Weimin Zhang, Qimin Zhan   +8 more
wiley   +1 more source

A Rare Case of Mucinous Carcinoma Arising in Association with an Intraductal Papilloma. [PDF]

Surg Case Rep
Yamasaki H, Kuba S, Akashi M, Morita M, Yukutake A, Hara Y, Tanaka A, Imamura H, Otsubo R, Matsumoto M, Kanetaka K, Matsumoto K, Eguchi S, Yamaguchi R.   +13 more
europepmc   +1 more source

Multifocal Digital Squamous Cell Carcinoma With Sarcoma Differentiation: A Case Report. [PDF]

Am J Case Rep
Xiang Y, Tan L.
europepmc   +1 more source

Involvement of increased arginase-1^<b>+</b> group 2 innate lymphoid cells and myeloid-derived suppressor cells in endometrial carcinoma: A pilot study. [PDF]

J Int Med Res
Gong Z, Lu Z, Pan A, Wang H, Yi H, Guo P, Bi K, Li X, Chen Y, Xu Y, Cao Y, Li C, Jiang H.   +12 more
europepmc   +1 more source

Early-Onset Bilateral Clear Cell Renal Cell Carcinoma in a Pediatric Renal Transplant Recipient: A Rare Case Report. [PDF]

Case Rep Urol
Gautam RK, Adhikari MB, Khadga A, Maharjan B, Shrestha PP, Mishra P, Yadav DK, Basnet B, Ghimire S, Parmar AS.   +9 more
europepmc   +1 more source

Hyperfunctioning distant metastases in high-grade differentiated thyroid carcinoma arising from HRAS-mutated follicular thyroid carcinoma: a case report and literature review. [PDF]

Front Endocrinol (Lausanne)
Park JY, Yoo SW, Kim SS, Hong AR, Yoon JH, Kim HK, Kang HC.   +6 more
europepmc   +1 more source

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Carcinoma cuniculatum: not a verrucous carcinoma

Journal of Cutaneous Pathology, 2012
BackgroundCarcinoma cuniculatum and verrucous carcinoma are both very well differentiated forms of squamous carcinoma and thus difficult to separate histologically from pseudocarcinomatous hyperplasia. The diagnosis of each often requires clinical‐pathologic correlation.MethodsWe reviewed the literature on cases reported as carcinoma cuniculatum and ...
M J, Kubik, R M, Rhatigan
openaire   +2 more sources