Results 21 to 30 of about 1,705,289 (268)

The CXCL5/CXCR2 axis contributes to the epithelial-mesenchymal transition of nasopharyngeal carcinoma cells by activating ERK/GSK-3β/snail signalling

Journal of Experimental & Clinical Cancer Research, 2018
Background Distant metastasis is the major cause of treatment failure in patients with nasopharyngeal carcinoma (NPC). Although several biomarkers correlate with metastasis and prognosis, the molecular mechanisms of NPC development and progression remain
Wen-Ze Qiu, Hai-Bo Zhang, Wei-Xiong Xia, Liang-Ru Ke, Jing Yang, Ya-Hui Yu, Hu Liang, Xin-Jun Huang, Guo-Ying Liu, Wang-Zhong Li, Yan-Qun Xiang, Tie-Bang Kang, Xiang Guo, Xing Lv   +13 more
doaj   +1 more source

Short‐term efficacy and long‐term survival of nasopharyngeal carcinoma patients with radiographically visible residual disease following observation or additional intervention: A real‐world study in China

Laryngoscope Investigative Otolaryngology, 2022
Background To explore the short‐ and long‐term outcomes in patients with nasopharyngeal carcinoma (NPC) with magnetic resonance imaging (MRI)‐detected residual disease at 3 months post‐treatment who received intervention either promptly (0 month) or ...
Ying‐Ying Huang, Xun Cao, Zhuo‐Chen Cai, Jia‐Yu Zhou, Xiang Guo, Xing Lv   +5 more
doaj   +1 more source

Incidence, consequences, and predictors of serious chemotherapy‐induced thrombocytopenia in nasopharyngeal carcinoma

Cancer Medicine, 2023
Objectives This study aimed to investigate the incidence, consequences, and predictors of serious chemotherapy‐induced thrombocytopenia (CIT) in nasopharyngeal carcinoma (NPC).
Lu‐Lu Zhang, Xi Chen, Ying‐Ying Huang, Chi‐Xiong Liang, Meng‐Yun Qiang, Zhuo‐Chen Cai, Ze‐Jiang Zhan, Ying Deng, Jia‐Yu Zhou, Hao‐Yang Huang, Xiang Guo, Xing Lv   +11 more
doaj   +1 more source

Spatial heterogeneity of immune infiltration predicts the prognosis of nasopharyngeal carcinoma patients

OncoImmunology, 2021
Spatial information on the tumor immune microenvironment is of clinical relevance. Here, we aimed to quantify the spatial heterogeneity of lymphocytes and cancer cells and evaluated its prognostic value in patients with nasopharyngeal carcinoma (NPC ...
Ya-Qin Wang, Xu Liu, Cheng Xu, Wei Jiang, Shuo-Yu Xu, Yu Zhang, Ye Lin Liang, Jun-Yan Li, Qian Li, Yu-Pei Chen, Yin Zhao, Jing-Ping Yun, Na Liu, Ying-Qin Li, Jun Ma   +14 more
doaj   +1 more source

Carcinoma of the Vagina [PDF]

Obstetrical & Gynecological Survey, 1978
Twenty-two patients with Stage I through IV primary vaginal squamous cell carcinomas treated for cure with radiation therapy are reviewed, with particular emphasis on the relationship of dose to complications and local control. All but 2 patients received 4000 to 6000 rad whole pelvis irradiation plus at least one radium application.
R B, Marcus, R R, Million, J W, Daly
openaire   +2 more sources

Adding Concurrent Chemotherapy Significantly Improves the Survival of Stage II-IVb Nasopharyngeal Carcinoma Patients Treated With Concurrent Anti-EGFR Agents

Frontiers in Oncology, 2021
ObjectiveAnti-EGFR Targeted agents were found to be capable of modulating the antitumor immunity in head and neck cancer and become more and more frequently used in the treatment of nasopharyngeal carcinoma(NPC).
Zi-Kun Yu, Zi-Kun Yu, Xu-Yin Chen, Xu-Yin Chen, Si-Han Liu, Si-Han Liu, You-Ping Liu, You-Ping Liu, Rui You, Rui You, Pei-Yu Huang, Pei-Yu Huang   +11 more
doaj   +1 more source

Identifying high-risk candidates for prolonging progression-free survival in primary gastric carcinoma subject to “double invasion”: an analytical approach utilizing lasso-cox regression

BMC Cancer
Objective To identify high-risk gastric carcinoma patients with concurrent vascular and neural invasion (“double invasion”) who are at heightened risk of progression-free survival (PFS) decline, enabling personalized clinical management.
Liwei Wang, Yu Chang, Jinfeng Ma, Wenqing Qu, Yifan Li   +4 more
doaj   +1 more source

TRIM21 inhibits irradiation-induced mitochondrial DNA release and impairs antitumour immunity in nasopharyngeal carcinoma tumour models

Nature Communications, 2023
The molecular mechanisms determining the response to radiotherapy remain incompletely understood. Here, the authors demonstrate that the E3 ubiquitin ligase and intracellular Fc receptor, TRIM21, impairs CD8+ T cell responses in nasopharyngeal carcinoma ...
Jun-Yan Li, Yin Zhao, Sha Gong, Miao-Miao Wang, Xu Liu, Qing-Mei He, Ying-Qin Li, Sheng-Yan Huang, Han Qiao, Xi-Rong Tan, Ming-Liang Ye, Xun-Hua Zhu, Shi-Wei He, Qian Li, Ye-Lin Liang, Kai-Lin Chen, Sai-Wei Huang, Qing-Jie Li, Jun Ma, Na Liu   +19 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

The Transcription Factor Creb is Involved in Sorafenib-Inhibited Renal Cancer Cell Proliferation, Migration and Invasion

Acta Pharmaceutica, 2018
Our previous reports showed that the cyclic-AMP-response element-binding protein (CREB) served as a proto-oncogene in the process of tumorigenesis and mediated the growth and metastatic activity of renal cancer cells.
Huang Shuaishuai, Cui Pinger, Lin Shuangxia, Yao Xuping, Wang Xue, Ren Yu, Weng Guobin   +6 more
doaj   +1 more source