Results 11 to 20 of about 5,039 (139)

STAT3/NF‐κB signalling disruption in M2 tumour‐associated macrophages is a major target of PLGA nanocarriers/PD‐L1 antibody immunomodulatory therapy in breast cancer

open access: yesBritish Journal of Pharmacology, Volume 178, Issue 11, Page 2284-2304, June 2021., 2021
Background and Purpose Inflammation associated with the tumour microenvironment (TME) is critical for cancer development, and immunotherapeutic strategies modulating the immune response in cancer have been crucial. In this study, a methotrexate‐loaded (MTX) poly(lactic‐co‐glycolic acid)‐based (PLGA) drug nanocarrier covered with polyethyleneimine (Pei)
Rômulo S. Cavalcante   +7 more
wiley   +1 more source

miR‐367 as a therapeutic target in stem‐like cells from embryonal central nervous system tumors

open access: yesMolecular Oncology, Volume 13, Issue 12, Page 2574-2587, December 2019., 2019
Aberrant expression of OCT4A and miR‐367 regulates stem‐like aggressive traits in embryonal central nervous system (CNS) tumor cells. We show that miR‐367 is carried by microvesicles derived from OCT4A‐overexpressing tumor cells, miR‐367 silencing reduces aggressive tumor traits, and treatment with miR‐367 inhibitor improves survival of tumor‐bearing ...
Carolini Kaid   +5 more
wiley   +1 more source

Label‐Free Proteomics Revealed Oxidative Stress and Inflammation as Factors That Enhance Chemoresistance in Luminal Breast Cancer

open access: yesOxidative Medicine and Cellular Longevity, Volume 2019, Issue 1, 2019., 2019
Breast cancer is the leading cause of cancer‐associated death among women worldwide. Its high mortality rate is related to resistance towards chemotherapies, which is one of the major challenges of breast cancer research. In this study, we used label‐free mass spectrometry‐ (MS‐) based proteomics to investigate the differences between circulating ...
Bruno R. B. Pires   +8 more
wiley   +1 more source

Combined Effects of Pericytes in the Tumor Microenvironment

open access: yesStem Cells International, Volume 2015, Issue 1, 2015., 2015
Pericytes are multipotent perivascular cells whose involvement in vasculature development is well established. Evidences in the literature also suggest that pericytes display immune properties and that these cells may serve as an in vivo reservoir of stem cells, contributing to the regeneration of diverse tissues.
Aline Lopes Ribeiro   +2 more
wiley   +1 more source

Reporte de Caso Carcinomas Renales Menos Frecuentes: Carcinoma de Ductos Colectores (Carcinoma de Bellini).

open access: yesRevista Guatemalteca de Urología, 2016
Los estudios morfológicos detallados y las técnicas moleculares contemporáneas y de inmunohistoquímica han resultado en las nuevas clasificaciones de neoplasias epiteliales renales. El carcinoma renal de células claras, papilar y células cromófobas 85 –
Edgar Alfredo Mansilla Guillén   +3 more
doaj   +1 more source

Hypernephroma Presenting with Cutaneous Leukocytoclastic Vasculitis and Lupus Anticoagulant: Resolution after Nephrectomy

open access: yesCase Reports in Urology, Volume 2012, Issue 1, 2012., 2012
Hypernephroma can present as a variety of paraneoplastic, nonmetastatic conditions, including vasculitis, and rarely a lupus‐type anticoagulant. Nephrectomy leads to the resolution of the systemic complaints. Malignancy, in this case hypernephroma, can present as an immune‐mediated paraneoplastic syndrome which resolves after removal of the underlying ...
Nigel P. Murray   +6 more
wiley   +1 more source

Cáncer Renal.

open access: yesRevista Guatemalteca de Urología, 2018
El diagnóstico y tratamiento del cáncer renal ha cambiado de forma importante en los últimos años. La incidencia mundial ha aumentado, pero la sobrevida también ha mejorado con el diagnóstico temprano de masas renales de forma incidental, debido al uso ...
Juan Pablo Lezana Vega
doaj   +1 more source

Carcinoma renal con cuadro clínico de infección urinaria recurrente en paciente joven

open access: yesAnales de la Facultad de Medicina, 2019
El cáncer renal es una neoplasia con una tasa de incidencia de 4,4% por 100 000 habitantes a nivel mundial; el carcinoma de células renales representa el 90% de los tumores renales malignos.
Roy R. Vasquez-Sullca   +3 more
doaj   +1 more source

Caso Clínico: Metástasis Tumoral a Tumor. Un Raro Fenómeno.

open access: yesOncología, 2019
Introducción: La metástasis tumor a tumor es muy rara con menos de 50 casos descritos en la literatura. Este artículo informa de un caso de metástasis de cáncer de mama  en un tumor renal de células claras.
Lorena Adriana Imba Chávez   +2 more
doaj   +1 more source

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