Results 31 to 40 of about 47,399 (199)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Digital morphometry illustrates a relationship between percentage of ductal carcinoma in-situ in breast needle core biopsy and margin status at lumpectomy

Journal of Pathology Informatics
Candidates for breast conserving surgery are selected based on imprecise variables and there is uncertainty surrounding the risk of complicated margins.
Alexander R. Gross, Gerald R. Hobbs, Jr., Luis Samayoa, Stell Santiago   +3 more
doaj   +1 more source

Importância da segunda opinião em patologia cirúrgica mamária e suas implicações terapêuticas Importance of a second opinion in breast surgical pathology and therapeutic implications

Revista Brasileira de Ginecologia e Obstetrícia, 2008
OBJETIVO: avaliar a concordância dos diagnósticos histopatológicos de lesões mamárias entre patologistas da comunidade e especialista em patologia mamária.
Márcio de Almeida Salles, Fernanda Squarcio Fernandes Sanches, Amanda Arantes Perez, Helenice Gobbi   +3 more
doaj   +1 more source

Mucocele like Tumour of the Breast Associated with Ductal Carcinoma in situ and Focal Ductal Carcinoma: What is the Best Approach to these Patients? [PDF]

Journal of Clinical and Diagnostic Research, 2016
Mucocele Like Tumours (MLT) of the breast are quite rare neoplasms displaying a broad spectrum. These lesions were considered benign initially. But now, they are believed to be related to atypical ductal hyperplasia, ductal carcinoma, or mucinous ...
Serdar Altinay, Safak Ersöz, Yavuz Üye, Feyyaz Özdemir   +3 more
doaj   +1 more source

US of Ductal Carcinoma In Situ [PDF]

RadioGraphics, 2002
Little is known about the ultrasonographic (US) features of ductal carcinoma in situ (DCIS) of the breast because this entity usually manifests as pure mammographic calcifications and is rarely evaluated with US. US findings were recorded in 70 patients with DCIS and then analyzed and correlated with mammographic and histologic findings.
Woo Kyung, Moon, Jae Sung, Myung, Yu Jin, Lee, In Ae, Park, Dong-Young, Noh, Jung-Gi, Im   +5 more
openaire   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Beyond the Fixed Charge: A New On‐Tissue Derivatisation Strategy Employing Photoionisable Chromophores for Mass Spectrometry Imaging of Amino‐Containing Metabolites

Angewandte Chemie, EarlyView.
We introduce a novel chemical derivatisation strategy for the UV‐activated detection of elusive metabolites. Incorporation of a tocopherol‐active chromophore allows for the detection of tagged analytes as photoionised radical cations, selectively induced by a 266 nm laser.
Sofia R. McGowan, Andrew J. Tague, Ashna A. Kumar, Marie Ranson, Christopher J. T. Hyland, Shane R. Ellis   +5 more
wiley   +2 more sources

A Juvenile Female with Ductal Carcinoma In situ Arising from a Fibroadenoma

Journal of Cancer Research and Practice, 2023
Ductal carcinoma in situ (DCIS) and atypical ductal hyperplasia are rare in teenagers. We report an incidental finding of DCIS in a 17-year-old girl who presented with a mass in the right breast. The pathology confirmed lower-grade DCIS in a fibroadenoma.
Wan-Yu Hung, Chih-Ling Lee, Chin-Yao Lin
doaj   +1 more source

Ductal Carcinoma In Situ: Pathology

Chirurgia, 2021
Ductal carcinomata in situ (DCIS) are both biologically and morphologically a heterogeneous group of neoplastic intraductal proliferations of the breast tissue, they represent an important precursor lesion for the development of invasive breast carcinoma and their diagnosis increases due to improved imaging.
openaire   +2 more sources

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source