Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova +4 more
wiley +1 more source
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley +1 more source
Multiparametric Breast MRI for the Differentiation of Atypical Ductal Hyperplasia and Ductal Carcinoma In Situ in Postmenopausal Women. [PDF]
Mihajlovic MN +5 more
europepmc +1 more source
The impact of immune microenvironment on local control of ductal carcinoma in situ receiving breast conservative therapy. [PDF]
Xu FF +6 more
europepmc +1 more source
Antipsychotic-Associated Galactorrhea May Mask Diffuse Ductal Carcinoma in Situ: A Diagnostic Challenge. [PDF]
Engele I +3 more
europepmc +1 more source
Spatially Discontinuous Mutation Topographies in Ductal Carcinoma In Situ Reveal Noncompetitive Growth Dynamics. [PDF]
Ryser MD +17 more
europepmc +1 more source
Radiation therapy in a ductal carcinoma in situ patient with ornithine transcarbamylase deficiency: a case report. [PDF]
Kang I +10 more
europepmc +1 more source
Nanoclay‐Engineered Scaffolds for the Controlled Delivery of Biomolecules in Regenerative Medicine
ABSTRACT Regenerative medicine combines biomaterials, cells, scaffolds, and bioactive agents via modern technologies to aid in the reconstruction and repair of damaged tissues. Among these, nanoclay scaffolds have demonstrated unique advantages in facilitating the delivery of therapeutic agents.
Mehri Shadi +2 more
wiley +1 more source
Semaphorin-7A promotes macrophage-mediated mammary epithelial and ductal carcinoma in situ invasion. [PDF]
Dahms PA +4 more
europepmc +1 more source
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source

