Results 131 to 140 of about 217,987 (265)

Incidence and Cancer Morbidity of Xeroderma Pigmentosum: A Swedish Population‐Based Register Study

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Xeroderma pigmentosum (XP) is a rare autosomal recessive condition associated with an extreme sensitivity to ultraviolet radiation. The XP incidence and cancer risk have been estimated in clinical cohorts but no population‐based analyses are available.
Theofanis Zagoras   +3 more
wiley   +1 more source

Descriptive study of stromal expression of CD73 in ductal carcinoma in situ of the breast. [PDF]

open access: yesDiscov Oncol
Catteau X   +8 more
europepmc   +1 more source

Refining OVCAR‐3 xenograft models of peritoneal carcinomatosis in nu/nu mice: Comparative intraperitoneal implantation strategies and the role of basement membrane matrix

open access: yesAnimal Models and Experimental Medicine, EarlyView.
A refined murine model of advanced ovarian cancer was established by comparing localized preperitoneal implantation and intraperitoneal injection of OVCAR‐3Luc cells. While localized implantation showed limited tumor persistence, intraperitoneal delivery with BME produced sustained diffuse dissemination confirmed by BLI and histology, providing a ...
M. Teresa Perelló‐Trias   +5 more
wiley   +1 more source

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

open access: yesAngewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean   +3 more
wiley   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher   +7 more
wiley   +1 more source

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