Results 71 to 80 of about 17,121 (220)

Clinicopathological and molecular characterization of HPV‐associated cervical poorly cohesive carcinoma: a rare aggressive entity

The Journal of Pathology: Clinical Research, Volume 12, Issue 4, July 2026.
Abstract Primary signet‐ring cell carcinoma and poorly differentiated adenocarcinoma with poorly cohesive morphology in the cervix are rare conditions, and their clinicopathological features remain poorly described. This study defines primary cervical poorly differentiated adenocarcinomas meeting the diagnostic criteria for poorly cohesive carcinoma as
Wei Liu, Xiao‐jiang Wang, Yan‐mei Cui, Jing‐cheng Liu, Jiajie Zhang, Li‐bin Zhang, Xi Lei, Xiuqin Weng, Wucheng Shen, Wen‐xiu Miao, Jun‐cheng Ye, Tong‐mei He, Qin Xu, Yi Shi, Dan Hu   +14 more
wiley   +1 more source

Advanced Uterine Carcinosarcoma With Fatal Suspected Pulmonary Embolism in a Resource‐Limited Setting: A Rare Case Report

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Uterine carcinosarcoma (UCS), also known as malignant mixed Müllerian tumor (MMMT), is a biphasic neoplasm characterized by the presence of carcinomatous (epithelial) and sarcomatous (stromal tissue) elements. It frequently presents at an advanced stage and can mimic primary ovarian carcinoma on clinical and radiological evaluation ...
John Lugata, Onesmo Mrosso, Tecla Lyamuya, Jasmine E. Arrington, Elizabeth Skinner, Bariki Mchome, Eusebious Maro, Alex Mremi   +7 more
wiley   +1 more source

A rare malignant thyroid carcinosarcoma with aggressive behavior and DICER1 gene mutation: a case report with literature review

Thyroid Research, 2018
Background Malignant biphasic tumor also known as carcinosarcoma is an uncommon neoplasm that is composed of both malignant epithelial and mesenchymal components. Most reported cases of carcinosarcoma affect the female genital tract; however, other sites
Jing Yang, Carmen Sarita-Reyes, David Kindelberger, Qing Zhao   +3 more
doaj   +1 more source

A living biobank of sarcoma patient‐derived cell cultures reveals multi‐omic and functional insights that capture disease heterogeneity

Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.
Preclinical models for sarcoma that preserve tumour biology are urgently needed to advance mechanistic understanding and functional precision oncology. 29 early‐passage patient‐derived sarcoma cell (PDC) cultures from 19 patients, representing 11 sarcoma subtypes were established and extensively characterized.
Stefanie Gijsels, Suzanne Fischer, David Creytens, Sándor Dedeyne, Felix De Vuyst, Cláudio Pinheiro, Fleur Cordier, Sarah‐Lee Bekaert, Nadine Van Roy, Kaat Durinck, Jarne Pauwels, Kris Gevaert, Pieter Mestdagh, Jo Vandesompele, Pekka Rappu, Jyrki Heino, An Hendrix, Gabrielle H. van Ramshorst, Gwen Sys, Olivier De Wever   +19 more
wiley   +1 more source

Impact of Allostatic Load on Overall Survival in Patients With Endometrial Cancer

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Introduction Endometrial cancer (EC) mortality is rising, with increasing rates of advanced disease and high‐risk histologic subtypes. Allostatic load (AL), a biomarker of cumulative physiologic stress, has been linked to cancer‐associated outcomes.
Nikita Sinha, Vanessa Miller, Alexandra Diggs, Emily Broaddus, Victoria Bae‐Jump, Olivia D. Lara   +5 more
wiley   +1 more source

Oophorectomy‐Corrected Ovarian Cancer Incidence, Survival, and Mortality by Subtype, Race, Ethnicity

Cancer Medicine, Volume 15, Issue 6, June 2026.
When combining ovarian, fallopian tube, and peritoneal sites, the decrease in ovarian cancer incidence is slower compared to ovarian cancer alone, suggesting reclassification of ovarian cancers as fallopian tube cancers. ABSTRACT Background Most ovarian cancers are detected at advanced stages, with poor outcomes.
Nicolas Wentzensen, Camryn Cohen, Summer Harvey, Britt K. Erickson, Megan A. Clarke   +4 more
wiley   +1 more source

Carcinosarcoma of the oesophagus – a rare mixed type of tumor

, 2010
Oesophageal carcinosarcoma is a rare type of oesophageal cancer composed of both squamous cells and sarcomatous cells. We report a case of a 71 year old man presenting with dysphagia and weight loss. Oesophagogastroduodenoscopy revealed a bulky mass with
Daniel Lee, Vinay Tak, Gainosuke Sugiyama, Hongbei Wang, Joyce T. Au, Wilson Ko, Anthony Nicastri   +6 more
core  

Carcinosarcoma of lung

, 2013
Primary carcinosarcoma of the lung is exceedingly rare. It is described as malignancy composed of a mixture of carcinoma and sarcoma elements. The sarcomatous element is usually spindle cell but may contain cartilage, bone or skeletal muscle. We report a
T Pathak, S Neupane, S Bastola, S Shrestha, CB Pun   +4 more
core   +1 more source

Outcome of adjuvant radiotherapy after total hysterectomy in patients with uterine leiomyosarcoma or carcinosarcoma: a SEER-based study

BMC Cancer, 2019
Background The clinical impact of adjuvant radiotherapy on uterine sarcoma is unclear, and may depend on the histological type. Hence, the aim of this study was to evaluate clinical outcomes of adjuvant radiotherapy after total hysterectomy in patients ...
Yuan Li, Haitao Ren, Junmei Wang
doaj   +1 more source

Integrating antibody–drug conjugates into solid tumor oncology: Current standards and future directions

Cancer, Volume 132, Issue S1, 1 June 2026.
Abstract Antibody–drug conjugates (ADCs) represent a major advance in precision oncology, combining the selectivity of monoclonal antibodies with the cytotoxic potency of chemotherapy. By enabling targeted intracellular delivery of highly potent payloads, ADCs aim to maximize antitumor activity while minimizing systemic toxicity. This review summarizes
André Mansinho, Joana Albuquerque, Andreia Lopes, Emiliano Calvo   +3 more
wiley   +1 more source