Results 151 to 160 of about 18,197 (205)

Determining properties of human‐induced pluripotent stem cell‐derived cardiomyocytes using spatially resolved electromechanical metrics

The Journal of Physiology, EarlyView.
Abstract figure legend In this study, we use human‐induced pluripotent stem cell‐derived cardiomyocyte (hiPSC‐CM) experiments and computational modelling to identify the mechanism of action of drug compounds. In the hiPSC‐CM experiments, optical measurements of cell collections are recorded in the baseline case and after drug exposure.
Karoline Horgmo Jæger, Verena Charwat, Kevin E. Healy, Samuel Wall, Aslak Tveito   +4 more
wiley   +1 more source

Assessment of cardiac allograft vasculopathy in heart transplant patients using multidimensional dynamic CTA and principal components analysis. [PDF]

BMC Med Imaging
Zhang X, Yang M, Huang T, Qin Q, Qian P, Luo Y, Wang J.   +6 more
europepmc   +1 more source

Calcium‐activated chloride channels in pericytes and their role in regulating organ blood flow

The Journal of Physiology, EarlyView.
Abstract figure legend Pericytes are microvascular mural cells with diverse roles. Contractile pericytes directly regulate local perfusion, while non‐contractile pericytes coordinate upstream vascular contractility via propagating electrical signals.
Paolo Tammaro, Hikaru Hashitani
wiley   +1 more source

Strategies for Aortic Root Measurement in Patients Undergoing Surveillance for Thoracic Aortic Disease. [PDF]

J Clin Med
Rana A, Hameed I, Dankwa S, Ahmad D, Best C, Asmelash S, Anzueto J, Talapaneni S, Cupo M, Bazarbaev A, Verma S, Lee C, Oden Shobayo T, Vallabhajosyula P.   +13 more
europepmc   +1 more source

Mechanisms underlying local Ca2+ signalling differences between right and left atrial myocytes at normal and increased frequencies

The Journal of Physiology, EarlyView.
Abstract figure legend Left atrial myocytes have TAT‐associated faster Ca2+ release but are more prone to maladaptation at higher frequencies due to weaker peripheral SR Ca2+ uptake and smaller trigger Ca2+ current. Abstract Changes in heart rate affect Ca2+ signalling and contractility in ventricular muscle, but the effects on atrial Ca2+ signalling ...
Joon‐Chul Kim, Hieu Trong Huynh, Phuong Kim Luong, Tran Nguyet Trinh, Yixuan Wu, Eleonora Grandi, Sun‐Hee Woo   +6 more
wiley   +1 more source

SMGDiff: step mapping generalized diffusion model for efficient noise reduction in cardiac-gated myocardial perfusion SPECT images. [PDF]

EJNMMI Phys
Li C, Huang J, Dong J, Liu C, Shi Y, Du Y, Lu Z, Cao C, Mok GSP, Wang H, Sun J.   +10 more
europepmc   +1 more source

Pulmonary arterial mechanoreceptors modulate exercise‐induced sympathetic activation in healthy humans during moderate‐intensity hypoxic exercise

The Journal of Physiology, EarlyView.
Abstract figure legend This randomized cross‐over trial (N = 12) addressed the hypothesis that selective reduction of pulmonary arterial pressure (i.e. manipulation of pulmonary arterial mechanoreceptor activation) during hypoxic exercise would reduce sympathetic outflow (muscle sympathetic nerve activity (MSNA)) in healthy humans.
Michiel T. Ewalts, Thomas D. Griffiths, Andrew J. M. Douglas, Elliott J. Jenkins, Guto Wyn Hughes, Craig D. Steinback, Lydia L. Simpson, Samuel J. Oliver, Mike Stembridge, Jonathan P. Moore   +9 more
wiley   +1 more source

Acute Traumatic Aortic Injury: What the Radiologist Needs to Know. [PDF]

Tomography
Ramirez-Garcia K, Jaramillo C, Ferguson E, Au J, Odisio E, Oderich GS, Ocazionez D, Duran C, Macedo T.   +8 more
europepmc   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

Role of Cardiac MRI and CT in Pericarditis and Pericardial Constriction. [PDF]

Methodist Debakey Cardiovasc J
Baser K, Ali N, Fakikh Y, Al-Kindi S, Al-Mallah M, Shah D, Malahfji M.   +6 more
europepmc   +1 more source