Results 91 to 100 of about 4,670,891 (357)

Unmet Cardiac Clinical Needs in Adult Mucopolysaccharidoses

Frontiers in Cardiovascular Medicine, 2022
The Mucopolysaccharidoses (MPSs) are a group of heterogenous disorders with complex multisystemic presentations. Although Haematopoietic Cell Transplantation (HCT) and Enzyme Replacement Therapy (ERT) have extended the lifespan of individuals affected ...
Karolina M. Stepien, Elizabeth A. Braunlin   +1 more
doaj   +1 more source

Following one's heart: cardiac rhythms gate central initiation of sympathetic reflexes [PDF]

, 2009
Central nervous processing of environmental stimuli requires integration of sensory information with ongoing autonomic control of cardiovascular function.
Critchley, Hugo D, Gray, Marcus A, Harrison, Neil A, Rylander, Karin, Wallin, B Gunnar   +4 more
core   +1 more source

Green Tea (Camellia sinensis) Extract Increased Topoisomerase IIβ, Improved Antioxidant Defense, and Attenuated Cardiac Remodeling in an Acute Doxorubicin Toxicity Model [PDF]

, 2021
Pamela Modesto, Bertha Furlan Polegato, Dos Santos, Letícia Dalla Vecchia Grassi, Leticia C. C. Molina, Silméia Garcia Zanati Bazan, Elenize Jamas Pereira, Ana Angélica Henrique Fernandes, Alexandre Todorovic Fabro, Vickeline N. Androcioli, Meliza Goi Roscani, Sérgio Alberto Rupp de Paiva, Leonardo Antônio Mamede Zornoff, Marcos Ferreira Minicucci, Paula S. Azevedo   +14 more
openalex   +1 more source

A Multi‐Center Retrospective Cohort Study of Neurosarcoidosis Myelitis: Current Observations and Future Directions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The optimal treatment for neurosarcoidosis myelitis is uncertain. We characterize incident neurosarcoidosis myelitis and assess treatment response by MRI and clinical scales. Methods Incident probable or definite neurosarcoidosis myelitis in adults was retrospectively identified from 13 academic medical centers.
Giovanna S. Manzano, Denis Balaban, Yihan Zhang, Brian Healy, Bart K. Chwalisz, Michael Levy, Nagagopal Venna, Barney J. Stern, Carlos A. Pardo, Paula Barreras, Nicole Bou Rjeily, Eoin P. Flanagan, Vyanka Redenbaugh, Allen J. Aksamit Jr., Spencer Hutto, Max Herman, Sally El Sammak, Elsa C. Rodriguez, Laura Snider, Hannah Rains, Mayra Montalvo, Torge Rempe, Sergi Martinez Ramirez, Lucas Horta, Stacey Clardy, Jennifer Lord, Tracey A. Cho, Lama Abdel Wahed, Joseph R. Berger, Rohini D. Samudralwar, Noellie Rivera Torres, David B. Clifford, Steven Richard Dunham, Masoud Majed, Aram Zabeti, Samuel Marcucci, Yang Mao‐Draayer, Jon Doty, Paunel B. Agyei, Shamik Bhattacharyya   +39 more
wiley   +1 more source

Diastolic dysfunction is associated with cardiac decompensation after transjugular intrahepatic portosystemic shunt in patients with liver cirrhosis [PDF]

, 2023
Hannah Rieland, Dominik Berliner, Lena Stockhoff, Marlene Reincke, Jim Benjamin Mauz, Bernhard Meyer, Johann Bauersachs, Heiner Wedemeyer, Frank Wacker, Dominik Bettinger, Jan B. Hinrichs, Benjamin Maasoumy   +11 more
openalex   +1 more source

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann, Michelle M. Sonsalla, Cora Luzinski, Fernando Zacahua, David A. Harris, Dudley W. Lamming, Albee Messing   +6 more
wiley   +1 more source

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini, Emanuela Martinuzzi, Sandra Dhifallah, Abderhmane Slioui, Angela Puma, Luisa Villa, Michele Cavalli, Andra Ezaru, Jérémy Garcia, Manuela Gambella, Federico Torre, Luca Jacopo Pavan, Nicolas Glaichenhaus, Sabrina Sacconi   +13 more
wiley   +1 more source

Transdiaphragmatic surgical access by thoracoscopy for epicardial pacemaker implantation in horses [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Cardiac arrhythmias are common in horses and can lead to a decline in performance and sudden death. The use of cardiac pacemakers in horses has been poorly investigated, with a scarcity of description and development of techniques for the device ...
A.R.C. Gomes, A.D. Lorga, L. Strugava, V.L. Bosak, J.C.D. Moreno, P.T. Dornbusch   +5 more
doaj   +1 more source

Utilization of Human Induced Pluripotent Stem Cells for Cardiac Repair

Frontiers in Cell and Developmental Biology, 2020
The paracrine effect, mediated by chemical signals that induce a physiological response on neighboring cells in the same tissue, is an important regenerative mechanism for stem cell-based therapy.
Chengming Fan, Chengming Fan, Eric Zhang, Jyotsna Joshi, Jinfu Yang, Jianyi Zhang, Wuqiang Zhu   +6 more
doaj   +1 more source

OPA1 mutation and late-onset cardiomyopathy: mitochondrial dysfunction and mtDNA instability. [PDF]

, 2012
BackgroundMitochondrial fusion protein mutations are a cause of inherited neuropathies such as Charcot-Marie-Tooth disease and dominant optic atrophy.
Bers, Donald M, Chen, Le, Chiamvimonvat, Nipavan, Cortopassi, Gino, Davies, Vanessa, Knowlton, Anne A, Liu, Tingting, Lu, Xiyuan, Tomilov, Alexey A, Tran, Alice, Votruba, Marcela   +10 more
core   +2 more sources