Enteric neuropathy and the vagus nerve: Therapeutic implications
Abstract Enteric neuropathies are characterized by abnormalities of gut innervation, which includes the enteric nervous system, inducing severe gut dysmotility among other dysfunctions. Most of the gastrointestinal tract is innervated by the vagus nerve, the efferent branches of which have close interconnections with the enteric nervous system and ...
Bruno Bonaz
wiley +1 more source
Case of Frozen Leads: An Old but Persistent Challenge
ABSTRACT Frozen leads are a rare but clinically relevant complication during cardiac device replacement. A 77‐year‐old man undergoing pacemaker upgrade had atrial and ventricular leads firmly adhered to the generator header despite set screw removal and ethanol application.
Takamasa Ishikawa+9 more
wiley +1 more source
Suspected cardiac amyloidosis: Endomyocardial biopsy remains the diagnostic gold‐standard [PDF]
Arnt V. Kristen+2 more
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Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker+2 more
wiley +1 more source
Implantable cardioverter defibrillator therapy in a patient with cardiac amyloidosis [PDF]
Mitsuru Itoh+9 more
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Skin Biopsy as a Diagnostic Tool for ATTRv Amyloid Neuropathy in the UK
ABSTRACT Objective Gene silencing therapy for ATTRv has revolutionised treatment. In minimally symptomatic, early neuropathic disease, skin biopsy can aid in the diagnosis of ATTRv‐PN, assessing both amyloid deposition and IENFD. Our aim was to study the value of performing skin biopsies in the diagnosis of ATTRv‐PN in UK patients and to assess the ...
Luke F. O'Donnell+10 more
wiley +1 more source
Transthyretin VAL107, a new variant associated with familial cardiac and neuropathic amyloidosis
Daniel R. Jacobson+2 more
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Treatment options for severe cardiac amyloidosis: heart transplantation combined with chemotherapy and stem cell transplantation for patients with AL-amyloidosis and heart and liver transplantation for patients with ATTR-amyloidosis☆ [PDF]
Falk‐Udo Sack+6 more
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Cystatin C as Biomarker for the Evaluation of Renal Outcome in AL Amyloidosis
ABSTRACT Cystatin C (CysC) has emerged as a novel and potentially more reliable biomarker for the estimation of glomerular filtration in the general population in patients with various conditions. In AL amyloidosis, the current renal staging system and renal response criteria are based on proteinuria and creatinine‐based eGFR.
Foteini Theodorakakou+18 more
wiley +1 more source