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Terapevticheskii arkhiv, 1981 Some of the next articles are maybe not open access.
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Current Treatment Options in Cardiovascular Medicine, 1999
No definitive therapy is available for cardiac amyloidosis. Treatment with alkylating agents such as melphalan has improved survival. Patients who do not respond to melphalan have benefited from high-dose chemotherapy with cyclophosphamide followed by peripheral stem cell transplantation.
, Kashyap, , Hosenpud
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No definitive therapy is available for cardiac amyloidosis. Treatment with alkylating agents such as melphalan has improved survival. Patients who do not respond to melphalan have benefited from high-dose chemotherapy with cyclophosphamide followed by peripheral stem cell transplantation.
, Kashyap, , Hosenpud
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The genetics of cardiac amyloidosis
Heart Failure Reviews, 2021Heritable cardiac amyloidosis (CA) is an underrecognized cause of morbidity and mortality in the USA. It results from the accumulation of the misfolded protein transthyretin within the myocardium, resulting in amyloid transthyretin-associated cardiomyopathy (ATTR-CM). Over 150 different pathologic point mutations within the transthyretin gene have been
Scott Arno, Jennifer Cowger
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Expert Review of Cardiovascular Therapy, 2014
Amyloidosis is a condition characterized by the extracellular deposition of insoluble fibrillar protein in tissues and various organs including the heart. This review summarizes the clinical manifestations and diagnostic treatment approaches for cardiac amyloidosis.
Syed Wamique, Yusuf +7 more
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Amyloidosis is a condition characterized by the extracellular deposition of insoluble fibrillar protein in tissues and various organs including the heart. This review summarizes the clinical manifestations and diagnostic treatment approaches for cardiac amyloidosis.
Syed Wamique, Yusuf +7 more
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Amyloidosis with cardiac involvement
Postgraduate Medical Journal, 2010A previously well man in his 70s presented with a 2 month history of progressive dyspnoea, peripheral oedema, and purpuric rash affecting his legs. On examination, he was hypoxic, had ascites, bipedal oedema, and purpura on his legs. Bloods revealed a normocytic anaemia, renal failure, and hypoalbuminaemia.
Adrian Sze Wai, Yong, Shahid, Aziz
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Echocardiography in cardiac amyloidosis
Heart Failure Reviews, 2015Echocardiography is the most widely used noninvasive test in patients with heart failure or abnormal cardiac findings on examination. Patients with amyloidosis may have significant cardiac abnormalities, several of which are highly suggestive of the disease. This article reviews echocardiographic features found in cardiac amyloidosis.
Rodney H, Falk, C Cristina, Quarta
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Cardiac transthyretin amyloidosis
Heart, 2012Cardiac amyloidosis of transthyretin fibril protein (ATTR) type is an infiltrative cardiomyopathy characterised by ventricular wall thickening and diastolic heart failure. Increased access to cardiovascular magnetic resonance imaging has led to a marked increase in referrals to our centre of Caucasian patients with wild-type ATTR (senile systemic ...
Jason N, Dungu +3 more
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American Heart Journal, 1953
Abstract Two cases of amyloidosis limited to the heart and one case of amyloidosis involving the heart and lungs are reported. All three patients were men in, or close to, the ninth decade of life. In all three cases auricular fibrillation and congestive failure were present. The literature is reviewed and a distinction drawn between systemic primary
A I, THOMASHOW +2 more
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Abstract Two cases of amyloidosis limited to the heart and one case of amyloidosis involving the heart and lungs are reported. All three patients were men in, or close to, the ninth decade of life. In all three cases auricular fibrillation and congestive failure were present. The literature is reviewed and a distinction drawn between systemic primary
A I, THOMASHOW +2 more
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Transthyretin Cardiac Amyloidosis
Current Cardiology Reports, 2017Transthyretin (TTR)-related cardiac amyloidosis is a progressive infiltrative cardiomyopathy that mimics hypertensive, hypertrophic heart disease and may go undiagnosed. Transthyretin-derived amyloidosis accounts for 18% of all cases of cardiac amyloidosis.
Anit K, Mankad, Keyur B, Shah
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