Results 71 to 80 of about 1,298,979 (289)

Progression of echocardiographic parameters and prognosis in transthyretin cardiac amyloidosis

open access: yesEuropean Journal of Heart Failure, 2022
Transthyretin amyloid cardiomyopathy (ATTR‐CM) is an increasingly diagnosed disease. Echocardiography is widely utilized, but studies to confirm the value of echocardiography for tracking changes over time are not available.
L. Chacko   +31 more
semanticscholar   +1 more source

Multi-Imaging Characterization of Cardiac Phenotype in Different Types of Amyloidosis [PDF]

open access: yes, 2023
Background: bone scintigraphy is extremely valuable when assessing patients with suspected cardiac amyloidosis (CA), but the clinical significance and associated phenotype of different degrees of cardiac uptake across different types is yet to be defined.
Brown, James   +19 more
core   +1 more source

Incidence and effect of secondary cardiac amyloidosis on outcomes of patients with t(11;14) multiple myeloma

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundThe t(11;14)(q13;32) is a common chromosome translocation in multiple myeloma (MM), but its prognostic value remains controversial. Immunoglobulin light chain amyloidosis is commonly secondary to multiple myeloma, which can rapidly cause heart ...
Jinghua Wang   +7 more
doaj   +1 more source

A Generalizable Deep Learning System for Cardiac MRI [PDF]

open access: yesarXiv, 2023
Cardiac MRI allows for a comprehensive assessment of myocardial structure, function, and tissue characteristics. Here we describe a foundational vision system for cardiac MRI, capable of representing the breadth of human cardiovascular disease and health.
arxiv  

Cardiac amyloidosis: clinical characteristics, prognostic factors and treatment [PDF]

open access: yes, 2020
Cardiac amyloidosis occurs when misfolded protein fibrils are deposited in the extracellular space of the myocardium. The most common causes for cardiac amyloidosis are light chain (AL) amyloidosis and transthyretin (ATTR) amyloidosis.
Patel, Ketna
core  

Wild-type transthyretin cardiac amyloidosis (ATTRwt-CA), previously known as senile cardiac amyloidosis: Clinical presentation, diagnosis, management and emerging therapies [PDF]

open access: yes, 2018
Cardiac amyloidosis is thought to be a rare group of diseases caused by extracellular deposition of misfolded proteins in the extracellular cardiac matrix resulting in heart failure with preserved ejection fraction (HFpEF).
Halatchev, Ilia G   +2 more
core   +2 more sources

Prevalence, Characteristics, and Impact on Prognosis of Aortic Stenosis in Patients With Cardiac Amyloidosis

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Cardiac amyloidosis (CA) is frequently found in older patients with aortic stenosis (AS). However, the prevalence of AS among patients with CA is unknown.
Mohamed‐Salah Annabi   +16 more
doaj   +1 more source

Nanobody interaction unveils structure, dynamics and proteotoxicity of the Finnish-type amyloidogenic gelsolin variant [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. Volume 1865, Issue 3, 1 March 2019, Pages 648-660, 2019
AGel amyloidosis, formerly known as familial amyloidosis of the Finnish-type, is caused by pathological aggregation of proteolytic fragments of plasma gelsolin. So far, four mutations in the gelsolin gene have been reported as responsible for the disease.
arxiv   +1 more source

A Descriptive Analysis of ATTR Amyloidosis in Spain from the Transthyretin Amyloidosis Outcomes Survey. [PDF]

open access: yes, 2021
Introduction Transthyretin amyloidosis (ATTR amyloidosis) is a clinically heterogeneous disease caused by mutations in the transthyretin (TTR) gene or aggregation of wild-type transthyretin (ATTRwt).
Amass, Leslie   +9 more
core   +1 more source

Transthyretin cardiac amyloidosis.

open access: yesMedicine and pharmacy reports, 2021
Transthyretin amyloid cardiomyopathy (ATTR-CM) may be an under recognized cause of heart failure (HF). TTR amyloidosis can be inherited, caused by variants in the TTR gene (ATTRv) or by deposition of wild-type TTR protein (ATTRwt), leading to high mortality if untreated.
Ioan Alexandru Minciună   +6 more
openaire   +3 more sources

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