Results 151 to 160 of about 357,051 (309)

Senescent Cell Derived Artificial Vesicle‐Based Senolytic Sonovaccine Platform with Augmented Lymph Node Delivery and Antigen Cross‐Presentation Efficacy

Advanced Science, EarlyView.
A senolytic sonovaccine platform (SenoVac) is developed, in which senescent cell‐derived vesicles serve as broad senescent cell antigen reservior. The “2‐step” click chemistry strategy for effective lymph node delivery, and ultrasound‐triggered endosomal escape to boost cross‐presentation, ensures efficient senescent cell clearance and disease ...
Liang Zhang, Yubo Lai, Jia Wang, Lingling Liu, Jieyuan An, Mi Qu, Yuan Liang, Bijun Tan, Guodong Yang, Xuekang Yang, Lijun Yuan   +10 more
wiley   +1 more source

Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice

Advanced Science, EarlyView.
Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li, Xijia Wang, Yaning Hu, Zhen Yang, Tian Niu, Xingbo Zhao   +5 more
wiley   +1 more source

Pulseless Electrical Activity Cardiac Arrest [PDF]

, 2020
Mannion, Matthew, McDowell, Christopher, Sembroski, Erik   +2 more
core  

Mitochondrial Carrier SLC25A13 Drives Ferroptosis Resistance and Immune Evasion via a STAT3–IFI6 Circuit in Breast Cancer

Advanced Science, EarlyView.
SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu, Yuhan Tang, Yingcui Chen, Zhuoqi Zhang, Yige Lu, Xinyue Wang, Qiyuan Shi, Wenhui Zhao, Hui Pang   +8 more
wiley   +1 more source

Temperature Control After In-Hospital Cardiac Arrest: Outcomes From the Discover In-Hospital Cardiac Arrest Cohort. [PDF]

Crit Care Med
Andrea L, Berg KM, Johnson NJ, Mitchell OJL, Pearce AK, Green A, Elmer J, Huespe IA, Lanspa MJ, Davis GR, Peltan ID, Herman NS, Malhotra R, Bangar MD, Peterson LN, Wadud N, Mayfield H, Vaena M, Valdez P, Howard TE, Loewe MR, Faiver L, Tam J, Halablab SM, Kaviyarasu A, Baram M, Chan V, Crisci T, Rosal N, Ghamande SA, White HD, Anderson B, Dugar S, Mehkri O, Saleem T, Vine J, Lee JH, Norton DL, Gaillard JP, Wachs T, Herbert JT, Krishnamoorthy V, Wardi G, Long MT, Craigova L, DeMasi SC, Shipley K, Khan A, Schnittke N, Hubel K, Crowley CP, Hansen CK, Dodd KW, Choudhury S, March C, Martinez A, Reyes A, Joffe AM, Bui A, Denchev K, Bissell Turpin BD, Fowajuh R, Ward J, Khan A, Chang C, Richieri E, Mirofsky M, Sagardia J, Piezny D, Gira AR, Cunto E, Khan R, Al-Hakim T, Gong MN, Moskowitz A, Discovery, the Critical Care Research Network of the Society of Critical Care Medicine.   +76 more
europepmc   +1 more source

Chronic Disease Monitoring Using Advanced Compliant Materials for Bioelectronics

Advanced Electronic Materials, EarlyView.
Compliant bioelectronic systems enable continuous monitoring of chronic disease through soft, stretchable materials and tissue‐conformal designs that support stable electrophysiological, mechanical, and biochemical sensing. Integration of diverse sensing modalities with thoughtful material selection, device architectures, and advanced fabrication ...
Han Kim, Mabel Bartlett, Liyang Wang, Karl Bates, Mengdi He, Myungbo Kim, Carmel Majidi, Tzahi Cohen‐Karni   +7 more
wiley   +1 more source

Point-of-Care Ultrasound Use in Cardiac Arrest Patients. [PDF]

Diagnostics (Basel)
Theophanous AG, Angeles N, Elizondo D, Bronshteyn YS, Theophanous RG.   +4 more
europepmc   +1 more source

Association of a Multimodal Perioperative Care Program With Postoperative Complications in Elderly Patients Undergoing Gastrectomy for Gastric Cancer

Annals of Gastroenterological Surgery, EarlyView.
Implementation of a multimodal perioperative care program and reduction of postoperative complications. ABSTRACT Purpose This retrospective study aimed to assess the clinical effectiveness of a multimodal perioperative care program in reducing postoperative complications in elderly patients undergoing gastrectomy for gastric cancer.
Keiichi Fujiya, Hiroshi Fuseya, Yusuke Yonenaga, Keiko Sanada, Toshimi Inano, Yumi Oguma, Kazuko Nakajima, Chikako Ando, Kumiko Oka, Yusuke Koseki, Kenichiro Furukawa, Yutaka Tanizawa, Masanori Terashima, Etsuro Bando   +13 more
wiley   +1 more source

Video Review of Cardiac Arrest: A Scoping Review. [PDF]

J Am Coll Emerg Physicians Open
Wolfsohn M, Ali M, Ramraj R, Li T, Morales J, Haddad G, Young E, Becker L, Rolston D, Jafari D.   +9 more
europepmc   +1 more source

Rethinking Perioperative Corticosteroids in Esophageal Cancer Surgery: Evidence From an Integrative Meta‐Analysis

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Esophagectomy remains a highly invasive procedure associated with substantial postoperative morbidity. Pulmonary complications, anastomotic leakage, and in‐hospital mortality are of particular concern. Perioperative corticosteroids are often administered to attenuate excessive inflammatory responses; however, the clinical impact in ...
Tomohiko Yasuda, Akihisa Matsuda, Nobutoshi Hagiwara, Yoshiharu Nakamura, Hiroshi Yoshida   +4 more
wiley   +1 more source