Results 191 to 200 of about 1,925,495 (406)

The Prognostic Value of Troponin-T in Out-of-Hospital Cardiac Arrest Without ST-Segment Elevation: A COACT Substudy [PDF]

open access: gold, 2023
Eva M. Spoormans   +36 more
openalex   +1 more source

Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest.

open access: yesNew England Journal of Medicine, 2002
Ashkan Mohammad H. Marissa Patrick Kara Alex Laurie Ali H Afshin Forouzanfar Reitsma Sur Estep Lee Marczak M   +153 more
semanticscholar   +1 more source

Evaluating the alignment of recent cardiac arrest randomized controlled trials with the top resuscitation science knowledge gaps

open access: yesResuscitation Plus
Objective: To determine if recently published cardiac arrest randomized controlled trials (RCTs) align with and address the top scientific gaps previously identified in the American Heart Association (AHA) cardiac arrest treatment guidelines.
Ryan A. Coute   +7 more
doaj   +1 more source

Midkine‐Mediated Microglia Activation after Renal Injury Promotes Cognitive Impairment Following Ischemic Renal Injury

open access: yesAdvanced Science, EarlyView.
The mechanism of secondary cognitive impairment following AKI. When renal ischemic injury progresses to fibrosis, renal fibroblasts and damaged tubular cells secrete MDK, which circulates through the bloodstream, crosses the damaged BBB, and accumulates in the hippocampus tissue (an area crucial for learning and memory).
Li Lu   +10 more
wiley   +1 more source

Peptide Electrostatic Modulation Directs Human Neural Cell Fate

open access: yesAdvanced Science, EarlyView.
This study explores the effect of charge on the bioactivity of peptide‐based supramolecular materials. The design of a peptide library with varying charges that self‐assemble into supramolecular fibers is presented, demonstrating how the surface charge of these fibers, used as artificial extracellular matrices, influences the fate of human neural ...
Laura Perez‐Chirinos   +10 more
wiley   +1 more source

CARDIAC ARREST [PDF]

open access: bronze, 1957
NULL AUTHOR_ID
openalex   +1 more source

Cardiac arrest and post-discharge mortality in patients with myocardial infarction: A large-scale nationwide registry analysis

open access: yesResuscitation Plus
Background: Cardiac arrest is a serious complication of acute myocardial infarction. The implementation of contemporary approaches to acute myocardial infarction management, including urgent revascularization procedures, has led to significant ...
Hirohiko Ando   +9 more
doaj   +1 more source

Multiscale Construction, Evaluation, and Application of Organoids

open access: yesAdvanced Science, EarlyView.
Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma   +5 more
wiley   +1 more source

Blocking Lysine Crotonylation and Aerobic Glycolysis as Targeting Strategy Against mpox Virus Replication

open access: yesAdvanced Science, EarlyView.
Wei et al. report that MPXV infection induces aerobic glycolysis, a process mediated by the viral protein I3 through lysine crotonylation at its K102 residue. The acetyltransferase MYST1 catalyzes the crotonylation of I3 to inhibit the ubiquitin‐mediated degradation of WDR26.
Pengjun Wei   +12 more
wiley   +1 more source

Therapeutic Reprogramming of Glioblastoma Phenotypic States Using Multifunctional Heparin Nanoparticles

open access: yesAdvanced Science, EarlyView.
This study presents heparin‐derived nanoparticles (HP‐NPs) as a novel precision medicine platform that combines therapeutic and delivery functions. HP‐NPs target drug‐resistant glioblastoma stem cells, reprogramming them into a drug‐sensitive phenotype and significantly reducing tumor progression.
Vadim Le Joncour   +14 more
wiley   +1 more source

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