Results 31 to 40 of about 1,076,384 (309)

The Impact of Tenapanor on Body Composition and Blood Pressure in Peritoneal Dialysis Patients: A Pilot Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida   +11 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Eleven years of experience with extracorporeal cardiopulmonary resuscitation for paediatric patients with in-hospital cardiac arrest

open access: yes, 2014
Purpose: The study aims to describe 11 years of experience with extracorporeal cardiopulmonary resuscitation (ECPR) for in-hospital paediatric cardiac arrest in a university affiliated tertiary care hospital.
Huang, Shu-Chien;Wu, En-Ting;Wang, Ching-Chia;Chen, Yih-Sharng;Chang, Chung-I;Chiu, Ing-Sh;Ko, Wen-Je;Wang, Shoei-Shen   +1 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Cardiac Arrest in a Community: Epidemiology, Treatment, and Outcome [PDF]

open access: yes, 2017
Background: Incidence and mortality from sudden cardiac arrest is high, making it a prevalent cause of death. Both incidence and survival rates show great variability between populations.
Buanes, Eirik Alnes
core   +1 more source

Responding to a cardiac arrest: Keeping paramedics safe during the COVID-19 pandemic [PDF]

open access: yes, 2020
This commentary aims to provide an overview of the current state and territory ambulance service cardiac arrest management recommendations to paramedics during the COVID-19 pandemic and highlight relevant risks to personnel.Full ...
Macquarrie, A, Whitfield, S, Boyle, M
core   +1 more source

Twenty years in the battle against sudden cardiac death:

open access: yesResuscitation Plus
Sudden cardiac arrest (SCA) is a life-threatening emergency that requires immediate intervention from lay responders. To address this critical need, the national Sudden Cardiac Arrest Foundation (SCAF) was established in 2005 to raise awareness, promote ...
Mary M. Newman   +5 more
doaj   +1 more source

Neuropsychological outcome after cardiac arrest: a prospective case control sub-study of the Targeted hypothermia versus targeted normothermia after out-of-hospital cardiac arrest trial (TTM2)

open access: yesBMC Cardiovascular Disorders, 2020
Background This study is designed to provide detailed knowledge on cognitive impairment after out-of-hospital cardiac arrest (OHCA) and its relation to associated factors, and to validate the neurocognitive screening of the Targeted Hypothermia versus ...
Erik Blennow Nordström   +18 more
doaj   +1 more source

A Retrospective Study: Quick Scoring of Symptoms to Estimate the Risk of Cardiac Arrest in the Emergency Department

open access: yesEmergency Medicine International, 2022
Purpose. At present, not enough is known about the symptoms before cardiac arrest. The purpose of this study is to describe the precursor symptoms of cardiac arrest, focusing on the relationship between symptoms and cardiac arrest, and to establish a ...
Yaoke Xu   +11 more
doaj   +1 more source

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