Results 41 to 50 of about 357,051 (309)

Pre-arrest and intra-arrest prognostic factors associated with survival after in-hospital cardiac arrest : systematic review and meta-analysis [PDF]

, 2019
: Objective: To determine associations between important pre-arrest and intra-arrest prognostic factors and survival after in-hospital cardiac arrest. Design: Systematic review and meta-analysis.
Cheng, Wei, Fernando, Shannon M., Guyatt, Gordon H., Harrison, David A, Kyeremanteng, Kwadwo, McIsaac, Daniel I., Nolan, Jerry P., Perry, Jeffrey J., Rochwerg, Bram, Rowan, Kathryn M., Taljaard, Monica, Tran, Alexandre, Vaillancourt, Christian   +12 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Validation of an ICD code for accurately identifying emergency department patients who suffer an out-of-hospital cardiac arrest. [PDF]

, 2018
AIM: International classification of disease (ICD-9) code 427.5 (cardiac arrest) is utilized to identify cohorts of patients who suffer out-of-hospital cardiac arrest (OHCA), though the use of ICD codes for this purpose has never been formally validated.
Abella, Benjamin S., Carr, Brendan G., Chukwulebe, Steve B., Gaieski, David F., Perman, Sarah M., Shelton, Shelby K.   +5 more
core   +1 more source

An evaluation of 9-1-1 calls to assess the effectiveness of dispatch-assisted cardiopulmonary resuscitation (CPR) instructions: design and methodology [PDF]

, 2008
Background Cardiac arrest is the leading cause of mortality in Canada, and the overall survival rate for out-of-hospital cardiac arrest rarely exceeds 5%.
Christian Vaillancourt, Manya L Charette, Ian G Stiell, George A Wells, I Jacobs, C Vaillancourt, RW Neumar, T Messner, ZJ Zheng, I Stiell, RO Cummins, IG Stiell, AP Hallstrom, M McCarthy, M Sekimoto, GL Larkin, YT Fong, GA Pane, ML Selby, R Swor, A Axelsson, RT Brennan, RA Swor, RA Waalewijn, RA Swor, C Alderman, MS Eisenberg, Anonymous, HR Arntz, A Axelsson, JW Bachman, J Bahr, PJ Baskett, P Chehardy, RE Jackson, KG Lie, KH Chu, SL Kivela, KK Lyda, LP Mandel, RA Swor, RJ Goldberg, A Flabouris, S Keim, PO Lejeune, J Demirovic, K Dracup, A Kliegel, PR Messmer, CA McLauchlan, DK Moser, KM Nelson, C Vaillancourt, M Jabbour, P Eisenburger, Anonymous, Heart and Stroke Foundation of Canada, Hd Alvarez, E Van Kerschaver, WR Gombeski Jr, LP Mandel, K Dracup, M Nelson, HJ Berden, M Fossel, ME Mancini, DK Moser, DK Moser, P Sefrin, E Wilson, LA Watson, DA Gass, E Su, FJ Weaver, CL Morgan, D Chamberlain, A Bang, SR Hauff, A Bang, AG Garza, AP Hallstrom, A Bang, RD Clark, MW Cooke, G Meron, LL Culley, A Hallstrom, A Hallstrom, C Vaillancourt   +88 more
core   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce, Goknur Selen Kocak, José Verdú‐Díaz, Jorge Alonso‐Pérez, Kristl G. Claeys, Tanya Stojkovic, Gorka Fernández‐Eulate, Pascal Laforêt, Najoua Miladi, Filipe Di Pace, Cristiane Araujo Martins Moreno, Edmar Zanoteli, Conrad C. Weihl, Volker Straub, Ana Töpf, Jordi Díaz‐Manera, Sarcoglycan European Cohort Consortium, Adele D′Amico, Adolfo López de Munain, Alicia Alonso‐Jiménez, Ana Camacho‐Salas, Andrea Gangfuß, Andrés Nascimento, Anna Sarkozy, Anneke J. van der Kooi, Arturo Fraga‐Bau, Béla Melegh, Benedikt Schoser, Bjarne Udd, Blaz Koritnik, Carlos Ortez, Chiara Marini Bettolo, Chiara Panicucci, Claudia Weiss, Claudio Bruno, Claudio Semplicini, Cristina Dominguez‐González, Cristina Garrido, David Gómez‐Andrés, Edoardo Malfatti, Elena Pegoraro, Elke De Vos, Francina Munell, Gabriele Dekomien, Giacomo Pietro Comi, Giorgio Tasca, Isabelle Richard, Jan L. De Bleecker, Jana Haberlová, Jesper Helbo Storgaard, Johanna Palmio, John Vissing, Juan Carlos de Leon‐Hernández, Kinga Hadzsiev, Laura Costa‐Comellas, Lea Leonardis, Leroy ten Dam, Lidia González‐Quereda, Luca Bello, Luisa Politano, Manuela Santos, Marianne de Visser, Marie Rohlenová, Matteo Garibaldi, Michela Guglieri, Nicolas Deconinck, Nicoline Løkken, Omar Abdel‐Mannan, Pia Gallano, Roberto Fernández‐Torrón, Ulrike Schara‐Schmidt, Vincenzo Nigro, Vittoria Zangaro   +72 more
wiley   +1 more source

The association between hemoglobin concentration and neurologic outcome after cardiac arrest. [PDF]

, 2016
PURPOSE: The purpose of the study is to determine the association between hemoglobin concentration (Hgb) and neurologic outcome in postarrest patients. METHODS: We conducted a retrospective cohort study using the Penn Alliance for Therapeutic Hypothermia
Dodampahala, Kalani, Gaieski, David F., Goyal, Munish, Grossestreuer, Anne V., Johnson, Nicholas J., Perman, Sarah M., Rosselot, Babette   +6 more
core   +1 more source

Postcardiac arrest syndrome: from immediate resuscitation to long-term outcome. [PDF]

, 2011
International audienceABSTRACT: Prognosis of post-cardiac arrest patients remains very bleak, not only because of anoxic-ischemic neurological damage, but also because of the "post-cardiac arrest syndrome", a phenomenon often enough severe to cause death
Cariou, Alain, Dumas, Florence, Grimaldi, David, Hissem, Tarik, Mongardon, Nicolas, Pène, Frédéric, Ricome, Sylvie   +6 more
core   +6 more sources

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Moderate Kidney Dysfunction Independently Increases Sudden Cardiac Arrest Risk: A Community‐Based Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Moderate kidney dysfunction is independently associated with increased cardiovascular death. Sudden cardiac arrest (SCA) accounts for at least 25% of chronic kidney disease (CKD) death.
Thien Tan Tri Tai Truyen, Audrey Uy‐Evanado, Harpriya Chugh, Kyndaron Reinier, David M. Charytan, Angelo Salvucci, Jonathan Jui, Sumeet S. Chugh   +7 more
doaj   +1 more source