Results 91 to 100 of about 279,139 (356)
Advanced Science, EarlyView.Our study reveals a novel mechanism of a positive regulatory circuit between Cav1.2 and H3K27ac for pancreatic neuroendocrine neoplasms (pNENs) progression. Cav1.2 is identified as a crucial target for promoting disease progression and correlates with malignant behaviors, which are remarkably inhibited by the administration of calcium channel blockers (
Yangyinhui Yu +12 more
wiley +1 more source
Calmodulinopathy: A Novel, Life-Threatening Clinical Entity Affecting the Young
Frontiers in Cardiovascular Medicine, 2018 Sudden cardiac death (SCD) in the young may often be the first manifestation of a genetic arrythmogenic disease that had remained undiagnosed. Despite the significant discoveries of the genetic bases of inherited arrhythmia syndromes, there remains a ...
Maria-Christina Kotta +10 more
doaj +1 more source
Advanced Science, EarlyView.This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang +7 more
wiley +1 more source
Negative tension of scroll wave filaments and turbulence in three-dimensional excitable media and application in cardiac dynamics [PDF]
, 2012 Scroll waves are vortices that occur in three-dimensional excitable media. Scroll waves have been observed in a variety of systems including cardiac tissue, where they are associated with cardiac arrhythmias.
Alonso, Sergio +2 more
core +2 more sources
Advanced Science, EarlyView.ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen +12 more
wiley +1 more source
BJS (British Journal of Surgery), EarlyView., 2020 All patients operated for oesophageal cancer in Sweden from 2013 to April 2018 were identified, and 246 patients were recruited to this population‐based nationwide Swedish study. The results show that longitudinal health‐related quality of life after minimally invasive oesophagectomy was similar to that of the open surgical approach.
F. Klevebro +4 more
wiley +1 more source
Beat by Beat: Classifying Cardiac Arrhythmias with Recurrent Neural Networks
, 2017 With tens of thousands of electrocardiogram (ECG) records processed by mobile cardiac event recorders every day, heart rhythm classification algorithms are an important tool for the continuous monitoring of patients at risk.
Delai, Marco +4 more
core +1 more source
Bidirectional ventricular tachycardia in cardiac sarcoidosis. [PDF]
, 2016 A 73-year-old man with history of pulmonary sarcoidosis was found to have runs of non-sustained bidirectional ventricular tachycardia (BVT) with two different QRS morphologies on a Holter monitor.
Benjamin, Mina M +4 more
core +2 more sources
Advanced Science, EarlyView.Fe‐based magnetic nanocubes conjugated with TRPV1 antibodies (FeNCs‐TRPV1) are developed for the specific targeting of TRPV1 channels. Intraspinally injected FeNCs‐TRPV1 induces TRPV1 desensitization in rats exposed to repetitive and transient ACMF.
Xueying Cheng +15 more
wiley +1 more source
Trials, 2019 Background The increasing use of implantable cardiac monitors (ICMs) allows early documentation of asymptomatic cardiac arrhythmias that would previously have gone unnoticed.
Christian Jons +5 more
doaj +1 more source