Results 231 to 240 of about 718,690 (296)

Cardiopulmonary Bypass Flow Rate and the Kidney: Comment. [PDF]

Anesthesiology
Desebbe O, Guinot PG, Fischer C, Joosten A.   +3 more
europepmc   +1 more source

ACLY‐Driven Metabolic Reprogramming Promotes Histone Acetylation and Inflammation‐Associated Fibrosis in Chronic Kidney Disease

Advanced Science, EarlyView.
This study reveals a citrate–ACLY–H3K27ac metabolic–epigenetic axis driving inflammatory gene activation and kidney fibrosis, highlighting ACLY inhibition as a potential therapeutic strategy for chronic kidney disease (CKD). ABSTRACT The mechanisms by which metabolic stress drives epigenetic dysregulation and fibrosis in chronic kidney disease (CKD ...
Chunxiu Du, Dhanunjay Mukhi, Lingzhi Li, Chenyu Li, Siyu Pan, Bernhard Dumoulin, Eunji Ha, Lakshmi P Kolligundla, Yanjuan Hou, Jonathan Levinsohn, Chaelin Kang, Konstantin Adrian Klötzer, Junnan Wu, Samer Mohandes, Kathryn E Wellen, Katalin Susztak   +15 more
wiley   +1 more source

Cardiac mediated cerebral blood flow changes in chronic hydrocephalus

Cerebrospinal Fluid Research, 2006
Fukamachi Kiyotaka, Leibson Zack, Leichliter Anna, Schenk Soren, Dombrowski Stephen M, Luciano Mark G   +5 more
doaj   +1 more source

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

Advanced Science, EarlyView.
Schematic representation of the role of lipophagy in bone mesenchymal stem cells(MSCs). In healthy MSCs, functional lipophagy efficiently degrades lipid droplets to support oxidative phosphorylation and cellular energy production, thereby facilitating osteogenic differentiation and matrix mineralization.
Chaoqiang Chen, Zhidong Liu, Yanhang Sun, Xiaojun Xu, Zhexiao Lan, Junhao Zhao, Peitao Xu, Guiwen Ye, Jinteng Li   +8 more
wiley   +1 more source

A numerical flow experiment for assessing the risk of rupture in anterior communicating artery aneurysms in relation to aneurysm projection. [PDF]

Sci Rep
Wiśniewski K, Tyfa Z, Dębska A, Zaczkowski K, Jaskólski DJ, Brandel MG, Inoue Y.   +6 more
europepmc   +1 more source

NET‐DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy‐Mediated Anoikis Resistance in Endometriosis

Advanced Science, EarlyView.
NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang, Yanling Gou, Huiyan Zhang, Hongli Wang, Beidi Wang, Jinming Liu, Yingying Cao, Ruru Bai, Yuxin Zhao, Xu Han, Chao Feng, Xin Huang, Zongfeng Zhang   +12 more
wiley   +1 more source

Integrating 4D-flow MRI and computational fluid hemodynamics to noninvasively estimate trans-stenotic pressure gradient in idiopathic intracranial hypertension. [PDF]

J Cereb Blood Flow Metab
Zhang Y, Song Y, Song S, Li X, Tong X, Miao Z, Mo D.   +6 more
europepmc   +1 more source

A transverse picoNewton force revealed in anisotropic Womersley flow. [PDF]

Sci Rep
Saqr KM.
europepmc   +1 more source

High-Frame-Rate Echocardiography: A New Frontier in Noninvasive Functional Assessment. [PDF]

J Clin Med
Mashayekhi F, Shahbazi F, Sousa AAA, Liu M, Voigt JU, Caenen A, D'hooge J.   +6 more
europepmc   +1 more source

Flow-driven left ventricular remodelling in long-term haemodialysis: a multicenter model of arteriovenous access-induced cardiac load. [PDF]

Ren Fail
Kyoda N, Ago R, Fukuma S, Masaki T.
europepmc   +1 more source