Results 61 to 70 of about 23,912 (290)

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Electrocardiographic Abnormalities and QTc Prolongation in Lupus Patients on Hydroxychloroquine in Tehran, Iran

Novelty in Biomedicine
Background: Hydroxychloroquine, a commonly prescribed treatment for systemic lupus erythematosus (SLE), has been associated with potential cardiac complications, including QTc prolongation.
Parisa Delkash, Soheila Sadeghi, Fatemeh Omidi   +2 more
doaj   +1 more source

ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells

Advanced Science, EarlyView.
With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao, Shannon Erhardt, Li Tang, Xiaotong Chen, Stephen M Farmer, Zixiu Cheng, Wen Chen, Ella Ziyuan Lu, Kihan Sung, Chang‐Ru Tsai, Mingjie Zheng, Sheng Zhang, Yang Liu, Jianxin Wang, Min Li, James F Martin, Jun Wang   +16 more
wiley   +1 more source

A Stretchable, Mechanically‐Interlocked Polyrotaxane Hydrogel for Wearable Motion and Electrophysiological Monitoring

Advanced Science, EarlyView.
A mechanically interlocked polyrotaxane hydrogel integrates sliding macrocycles within a covalent network, yielding skin‑like softness, high stretchability, robust adhesion, and stable ionic conductivity. This multifunctional interface enables simultaneous high‑fidelity monitoring of human motion and epidermal electrophysiological signals (ECG/EMG ...
Hao‐Zheng Huang, Yu‐Tao Zheng, Feng Chen, Jing‐Yi Li, Wen‐Hui Zhang, Liang Ding, Zhegang Huang, Wei Jiang, Li‐Ping Huang, Xing‐Can Shen   +9 more
wiley   +1 more source

Arritmias cardiacas durante la prueba de esfuerzo en sujetos supuestamente sanos

Revista Cubana de Medicina, 1996
Se estudiaron 80 jóvenes supuestamente sanos con edades comprendidas entre 21 y 30 años mediante una prueba de esfuerzo máximo en veloergómetro para provocar arritmias cardíacas y hacer su diagnóstico clínico.
Ruth E. Reyes Sánchez, Eduardo Alvarez Acevedo, Ernesto Velarde Sosa   +2 more
doaj  

Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice

Advanced Science, EarlyView.
Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li, Xijia Wang, Yaning Hu, Zhen Yang, Tian Niu, Xingbo Zhao   +5 more
wiley   +1 more source

A case of tacrolimus-induced supraventricular arrhythmia after kidney transplantation

São Paulo Medical Journal
CONTEXT Tacrolimus is a potent immunosuppressive drug often administered to transplant recipient patients and exhibits a variety of adverse cardiovascular effects.
Bo-Ra Kim, Ho-Sik Shin, Yeon-Soon Jung, Hark Rim   +3 more
doaj   +1 more source

Heart rate turbulence in patients with stable coronary artery disease and its relationship with the severity of the disease

Türk Kardiyoloji Derneği Arşivi, 2015
OBJECTIVE: Heart rate turbulence (HRT) indicates the impairment of cardiac autonomic function. With the literature containing insufficient information on HRT in stable coronary artery disease (CAD), this study aimed to investigate the role of HRT in ...
Onur Baydar, Veysel Oktay, Ümit Yaşar Sinan, Uğur Coşkun, Ahmet Yıldız, Okay Abacı, Tevfik Gürmen, İnci Fıratlı   +7 more
doaj   +1 more source

An Implantable Phototriggered Prodrug Depot Patch Enables Actively Programmable Drug Release for Post‐Myocardial Infarction Therapy

Advanced Science, EarlyView.
An implantable phototriggered prodrug depot patch (iPDP) is presented that enables actively programmable drug release post‐implantation. Covalently conjugated prodrug ensures minimal leakage; illumination parameters serve as a code to precisely control dose per release.
Haipeng Lu, Kaicheng Deng, Zhang Zhang, Qirui Wang, Weijing Gao, Liyin Shen, Lei Zhang, Wenting Hu, Yang Zhu, Zhengwei Mao, Tanchen Ren   +10 more
wiley   +1 more source

Feasibility, safety and tolerability of accelerated dobutamine stress echocardiography

Cardiovascular Ultrasound, 2007
A continuous infusion of a single high dose of dobutamine has been, recently, suggested as a simple and effective protocol of stress echocardiography.
Pavaci Herribert, Pino Paolo G, Pulignano Giovanni, Manzara Carla, Minardi Giovanni, Sordi Martina   +5 more
doaj   +1 more source